JPH11113779A - Sterile wet tissue - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide highly safe antimicrobial wet tissue which makes it possible to obtain a high sterilization capability and uniform sterilization effect without using alcohols, maintains the sterilization effect for long, does not induce the roughening of the skin, etc., in spite of long-term use and has no problems in spite of injection oral administration. SOLUTION: A nonwoven fabric contg. 10 to 100 wt.% cellulose fibers is impregnated with an aq. soln. contg. polylysine and/or its salt and glyceric fatty acid ester at 0.5 to 5 times weight to the nonwoven fabric in this sterille wet tissue. The aq. soln. contains the polylysine in a range of 0.01 to 1 wt.% and the glyceric fatty acid ester of 0.1 to 5 wt.%. The polylysine is ε-polylysine and the glyceric fatty acid ester may be caprylic acid or the monoester of at least one fatty acid among either of the caprylic acid and lauric acid, and glycerin.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a disinfecting wet tissue, and more particularly, to an excellent disinfecting agent, harmless to the human body and harmless to the skin, and for cleaning personal belongings of babies and sick persons. The present invention relates to a disinfecting wet tissue suitable for cleaning living spaces such as kitchens, refrigerators and toilets, cleaning food and food containers, or as a freshness preserving sheet for wrapping fruits and vegetables.

[0002]

2. Description of the Related Art In recent years, diversification of lifestyles has led to an increase in feelings of comfort and hygiene, and in particular, there has been a strong demand for antibacterial properties and deodorant properties of human bodies and lifestyle-related products. In particular, in modern times when the comfort and tightness of the living space have been increased, moderate temperatures and humidity can be maintained even in winter, and various bacteria and molds are easy to propagate, and the harm is occurring frequently. Some of the skin diseases that have been increasing in recent years are thought to be caused by such abnormally propagated bacteria.

[0003] Also, there is an increasing demand for antibacterial and deodorizing products used in medical institutions and similar institutions, so-called medical-related products. For example, a major problem in medical institutions in recent years has been the emergence of bacteria that are resistant to antibiotics. These cause sepsis, mycosis, etc. in a human body with reduced resistance, and in the worst case, even lead to death. In the future, it is thought that the elderly problem will be greatly highlighted as a social problem. For example, bedridden elderly people at home are troubled by abnormal odors caused by bedsores, infectious diseases and the like, and these are also caused by abnormally occurring bacteria.

[0004] Therefore, there is a long-felt need for hygienic and comfortable products that suppress the growth of microorganisms, and various methods for antibacterial properties have been proposed. For example, various methods have been adopted as a method for cleaning the human body and daily necessities, and the use of wet tissue is a typical method. Generally, a wet tissue is used in a state where an aqueous solution containing water as a main component is impregnated into a fabric such as a nonwoven fabric. By wiping the human body and sundry goods with such a wet tissue, dust and dirt on these surfaces can be more efficiently removed, and thus are effectively used as a product for improving hygiene and comfort. The aqueous solution used in these wet tissues contains a compound for maintaining water retention, a compound for preventing drying and spoilage, and a fragrance.

[0005] However, the above-mentioned wet tissue has a cleaning effect of removing dirt and dust, but has almost no germicidal effect of removing bacteria and the like attached to the surface. For this reason, various methods for imparting disinfecting properties have been proposed with an increasing desire for comfort and hygiene. For example, a wet tissue using an aqueous solution containing an alcohol such as ethanol or isopropanol at a high concentration of about 70% has been proposed (JP-A-64-22804,
JP-A-5-15468). However, in a wet tissue using a high concentration of alcohol, alcohol-
Because of its high volatility, it has a problem that it gives off an irritating odor during use, gives an unpleasant cooling sensation to the human body, and causes rough skin by wiping even the oil and fat components of the skin. Further, alcohols have a disinfecting effect when wiped, but if they are volatilized, the disinfecting property is lost, and after a while, there is a problem that they are contaminated by bacteria and the like.

[0006] In order to improve these, a wet tissue impregnated with an aqueous solution containing a general antibacterial agent, for example, a quaternary ammonium salt such as benzalkonium chloride, and an antibacterial compound such as paraoxybenzoic acid has been proposed. (JP-A-3-16542, JP-A-6-469)
No. 68, Japanese Utility Model Publication No. 60-163914). However, when these compounds are used as antibacterial agents, the antibacterial properties are weaker than wet tissues using high-concentration alcohols, so that bacteria have not been eliminated. Also, if a material with high antibacterial performance is used or the amount added is increased in order to obtain the same degree of bactericidal effect as alcohols, irritation to the skin becomes stronger than alcohols, causing itching and rash There was a problem. In addition, wet tissue is often used to wipe around the mouth, clean toys for babies, fruits such as apples and pears, and spoons and tableware for outdoor use such as direct cleaning. The compound is used only at a safe level for the human body, and is not preferable in terms of oral toxicity and the like in terms of hygiene and safety.

In order to reduce the alcohol content, a wet tissue impregnated with a mixture of the above compound and alcohol has been proposed (JP-A-1-143808).
No.). However, also in this case, since the concentration of alcohols is low, it is necessary to use a compound having high antibacterial performance or to increase the amount of addition, which is not preferable for the human body. Furthermore, a wet tissue considering the safety of the human body has been proposed. For example, Japanese Patent Application Laid-Open
No. 25821 discloses adding a chitosan salt,
Japanese Patent Application Laid-Open No. Hei 3-29623 proposes adding a tea extract to deodorize. However, the disinfection effect of these compounds was weak, and it was hard to say that it was a disinfection wet tissue.

On the other hand, in addition to wet tissues, food preservatives and food preservative ethanol preparations that effectively work against various bacteria have been proposed in consideration of the safety of foods directly entering the body. . For example, Japanese Unexamined Patent Publication (Kokai) No. 62-58975 discloses a food preservative containing a mixture of e-polylysine and a diluent such as lower fatty acid monoglyceride.
No. 075 discloses an ethanol preparation for food preservation in which polylysine and glycerin middle and lower fatty acid esters are added to ethanol.

[0009] These preparations are required to be free of bacteria in the preparation itself during storage and to have the ability to disinfect the attached state by spraying or applying to the object. . On the other hand, for wet tissue,
As a matter of course, it is required that mold does not grow on the wet tissue and that it can be sterilized by the chemical leached from the tissue when wiped off with the tissue. As described above, the chemical solution of the wet tissue plays a role of preventing contamination by bacteria on the tissue, and that the chemical solution once retained in the tissue leaches out of the tissue to remove bacteria, and the role of the above-described preparation. Therefore, it was difficult to use these preparations as they were as chemicals for wet tissues. By spraying or applying the above formulation, the formulation adheres to the target as water droplets,
Due to repelling, uniform adhesion could not be achieved, and there was a case where the bactericidal property was not sufficiently exhibited.

[0010]

DISCLOSURE OF THE INVENTION The present invention solves the above-mentioned problems of the prior art, and can achieve a high sterilization ability and a uniform sterilization effect without using alcohols. The present invention provides an antibacterial wet tissue that has a long-lasting bacterial effect, does not cause skin roughening even when used for a long period of time, and has no problem even when taken orally and has high safety.

[0011]

The invention claimed in the present invention is as follows. (1) An aqueous solution containing polylysine and / or a salt thereof and a glycerin fatty acid ester was impregnated into a nonwoven fabric containing 10 to 100% by weight of cellulose fibers by 0.5 to 5 times the weight of the above nonwoven fabric. Disinfection wet tissue characterized by the above. (2) The aqueous solution contains 0.01 to 1% by weight of polylysine.
And glycerin fatty acid ester in the range of 0.1 to 5% by weight, and the polylysine is ε-polylysine, and the glycerin fatty acid ester is a monoester of glycerin with at least one fatty acid of caprylic acid, capric acid and lauric acid. The disinfected wet tissue according to (1), wherein

[0012]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in detail.
The nonwoven fabric used in the present invention is a natural fiber cotton, a regenerated fiber obtained by chemically dissolving and regenerating a natural material, a cupra fiber,
It contains 10 to 100% by weight, preferably 50 to 100% by weight of cellulosic fibers such as rayon fibers. The nonwoven fabric containing the cellulose fiber in an amount of 10% by weight or more has excellent water absorbability, excellent liquid retaining property of an aqueous solution, and excellent touch when used for personal use.

The fibers other than the above-mentioned cellulosic fibers include pulp and chemically synthesized and spun synthetic fibers such as acrylic fiber, polyparaphenylene fiber, vinylon fiber, polyurethane fiber, polyvinyl chloride fiber, nylon 6, nylon 66, polyamide fibers such as nylon 610, polyester fibers such as polyethylene terephthalate and polybutylene terephthalate, and polyolefin fibers such as polyethylene and polypropylene.
A mixture of more than one species can be used. In particular, those obtained by laminating cellulosic fibers on a nonwoven fabric made of ultrafine fibers or crimpable fibers can exhibit a high cleaning effect depending on the surface area of the fibers and the size of the voids.

The polylysine used in the present invention can be produced, for example, by the production method described in JP-B-59-20359, that is, Streptomyces albras subsp., A polylysine-producing bacterium belonging to the genus Streptomyces.
It can be obtained by culturing a seed lysinopolymeras in a medium, separating and collecting ε-polylysine from the obtained culture. Polylysine can be used in a free form, but it should be used in the form of an inorganic acid salt with hydrochloric acid, sulfuric acid, phosphoric acid, etc. or an organic acid salt with acetic acid, propionic acid, fumaric acid, malic acid, citric acid, etc. Can also.

Such a polylysine exhibits an antibacterial effect against airborne bacteria such as Escherichia coli and Staphylococcus aureus, bacteria resident on the skin, and bedsores such as Pseudomonas aeruginosa. Although polylysine does not have a very high antifungal property against molds, it can supplement the antifungal property by using it in combination with a glycerin fatty acid ester described later. Polylysine is 0.01 to 1% by weight in the aqueous solution impregnating the nonwoven fabric.
Is preferably contained in the range of, more preferably, 0.1.
1 to 0.5% by weight. If the amount used is less than 0.01% by weight, the antibacterial effect and the antifungal effect may not be sufficiently exhibited, and if the amount exceeds 1% by weight, the effect is not improved and it becomes uneconomical.

The glycerin fatty acid ester used in the present invention is an ester of glycerin and a linear fatty acid,
One type or a mixture of two or more types can be used. As the straight-chain fatty acid, a fatty acid having 8 to 12 carbon atoms is preferable, and caprylic acid, capric acid, and lauric acid are particularly preferable. Fatty acids such as acetic acid, particularly fatty acids having 12 or less carbon atoms have a strong antibacterial effect, and esters with glycerin, which can soften the odor and stimulus peculiar to the fatty acids, also show a strong antibacterial effect. As an ester with glycerin, a monoester is preferably used from the viewpoint of an antibacterial effect. Diesters or triesters may not be able to achieve the antibacterial effect.

The chemical solution used for the wet tissue is easily soluble in water, has an antifungal property to prevent molds such as black mold and blue mold from growing on the tissue during storage, and has a property against fungi such as yeast and mold. It is necessary to have a disinfecting property, and in view of this point, a monoester with caprylic acid which is a fatty acid having 8 carbon atoms or capric acid which is a fatty acid having 10 carbon atoms is most preferable. In order to improve the solubility stability of the glycerin fatty acid ester in water, a polyglycerin fatty acid ester or propylene glycol can be added. Glycerin fatty acid esters, along with antifungal properties against molds, E. coli,
It has antibacterial properties against bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa, and can supplement the antibacterial properties of polylysine.

The amount of the glycerin fatty acid ester used is preferably 0.1 to 5% by weight, more preferably 0.25 to 3% by weight, based on the aqueous solution. If the amount used is less than 0.1% by weight, the antibacterial and antifungal effects cannot be sufficiently exerted. If the amount exceeds 5% by weight, the aqueous solution may become slimy and the touch feeling when used as a wet tissue may be reduced.
In addition, the cost increases.

To the aqueous solution used in the present invention, in addition to the above-mentioned polylysine and glycerin fatty acid ester, a bamboo extract, hinokithiol, protamine, a tea extract, lysozyme, chitosan, etc. are added as required. Is also good.
However, it is desirable that the substance has been confirmed to be safe for the human body, such as polylysine and glycerin fatty acid ester. In addition, additives generally used in liquid chemicals for wet tissues, for example, humectants such as glycerin, propylene glycol and polyethylene glycol, solubilizers such as dextrin, lactic acid, sodium lactate, malic acid, citric acid A pH adjuster such as an acid, tartaric acid, and succinic acid, a thickener, a dye, an antioxidant, a surfactant and the like may be used as desired. Also in this case, it is desirable to use additives that can ensure safety for the human body and that are hygienic.

The amount of the aqueous solution containing polylysine and glycerin fatty acid ester impregnated in the tissue nonwoven is 0.5 to 5 times, preferably 1 to 3 times the weight of the tissue nonwoven. . If the impregnation amount is less than 0.5 times the weight, the aqueous solution cannot uniformly impregnate the nonwoven fabric, and if it exceeds 5 times the weight, the aqueous solution may stick to the hand more than necessary at the time of use, or may fall down when taken out. Drip and the handling becomes poor.

The disinfected wet tissue of the present invention can be obtained by impregnating an aqueous solution containing polylysine and a glycerin fatty acid ester into the above-mentioned specific nonwoven fabric by a known method. It has excellent bactericidal properties and is highly safe for the human body and skin. That is, since the disinfecting wet tissue of the present invention contains polylysine and glycerin fatty acid ester, it prevents the growth of bacteria on the tissue during storage, wipes the human body and articles, and is present on the human body and articles. The wiping effect exerted by physically removing the bacteria and the antibacterial effect exerted by the aqueous solution of the wet tissue attached to the wiped part coming into contact with the bacteria can uniformly disinfect the human body and articles. it can.

Further, since polylysine and glycerin fatty acid ester do not easily volatilize in the air, they remain on the human body and articles even after wiping off, exhibit an antibacterial effect, and maintain sterilization. That is, even if the bacteria adhere again after the wiping and elimination, the antibacterial effect works and the bacteria are not contaminated again. Polylysine is produced by bacteria and is used as a natural food additive.Furthermore, glycerin fatty acid ester is also certified as a food additive. Has been confirmed.

For this reason, the sanitizing wet tissue of the present invention is excellent in sanitizing properties and high in safety, so that it can be used as a personal sanitizing wet tissue for wiping skin such as fingers and buttocks, and for babies and the elderly. Purification of personal belongings, cleaning of living spaces such as kitchens and toilets, sterilization wet tissue for purposes such as cleaning of food containers, chopsticks, spoons etc. used outdoors and indoors, as well as freshness wrapping fruits and vegetables It can be used as a holding sheet and as a disinfecting wet tissue for various uses such as for cleaning the human body and for cleaning miscellaneous goods used in medical institutions and home nursing as medical uses.

[0024]

EXAMPLES Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples. In addition,% in an example shows a weight% unless there is particular limitation. Further, the tests of antibacterial and antifungal properties, disinfecting properties, disinfection maintaining properties and skin roughness in the examples were carried out by the following methods. (1) Measurement of antibacterial and antifungal properties The test for antifungal properties of samples was carried out by the halo method (JIS L1902).
-1990). That is, a conidia of one test tube of black mold (IFO-4414) grown on a Sabouraud agar medium (10 ml) for preservation of black mold was added together with mycelium to 10 ml of a spore dispersant (0.005% dioctylsulfosuccinic acid). Disperse, filter with sterile cotton wool,
The plate was dissolved and added to 100 ml of Sabouraud agar medium kept at 45 ° C., and 10 ml was dispensed per plate to prepare a plate medium.

The sample was cut into a size of 2 cm × 2 cm, placed on the prepared medium, and cultured at 25 ° C. for 7 days. As the evaluation, a growth inhibition zone (halo-) was placed around the sample.
(-), Those with no growth of bacteria on the sample (-), and those with growth of bacteria on the sample were (+). In order to measure the bacterial concentration, 1 ml of the bacterial solution added to the Sabouraud-agar medium was added to 9 ml of a 0.005% dioctylsulfosuccinic acid solution, and this operation was repeated to carry out serial dilutions. After the mixture was chilled and solidified, it was cultured at 25 ° C. for 7 days and the number of bacteria was measured.

Similarly, the test for antibacterial activity was evaluated by the halo method. The bacteria used were Pseudomonas aeruginosa (IFO-3080) and Escherichia coli (IFO-3301), which were added to a normal agar medium at a bacterial concentration of about 10 ⁶ cells / ml, and 10 ml was dispensed per dish. To give a plate medium. As fungi, Candida albican (Candida albican)
s; ATCC14053) was added to a Sabouraud-agar medium to give a bacterial concentration of about 10 ⁶ cells / ml, and 10 ml was dispensed per plate to obtain a plate medium. Other methods were the same as described above, and the cells were cultured at 37 ° C. for 24 hours and evaluated as above. In addition, the bacterial concentration was also measured using a bacterial solution serially diluted with physiological saline, and Pseudomonas aeruginosa and Escherichia coli were diluted with an ordinary agar medium, and Candida bacteria were diluted with a Saburo-agar medium and cultured at 37 ° C. for 24 hours. Measured.

(2) Bactericidal test 1 ml of a bacterial solution such that the concentration of Staphylococcus aureus (ATCC 6538P) was about 10 ⁶ cells / ml was applied to a sterilized slide glass placed in a sterile dish. This was wiped with a sample, and in order to wash out residual bacteria on the slide glass, physiological saline + surfactant polyoxyethylene (2
0) Sorbitan monooleate (Tween80 etc.)
Immediately, 10 ml of the 0.2% solution was added, followed by thorough stirring.
From this, 0.1 ml was spread on an ordinary agar medium and cultured at 37 ° C. for 24 hours to measure the number of bacteria. At the same time, in order to measure the number of bacteria on the sample after wiping, put the sample in a sterilized vial, incubate at 37 ° C. for 0.6, 24 hours, add the same washing solution as above, and count the bacteria. Was measured.

(3) Persistence test of sterilization The sterilized slide glass put in the sterilized dish was wiped with the sample, and the lid of the dish was shifted and left for 0, 1, 4, 7, and 24 hours. Thereafter, Staphylococcus aureus (ATCC6
538P) was applied to a 0.1 ml slide glass so as to have a bacterial concentration of about 10 ⁵ cells / ml. After 10 minutes, a 0.2% solution of physiological saline + a surfactant polyoxyethylene (20) sorbitan monooleate (Tween 80 or the like) was added to the slide glass to wash out residual bacteria on the slide glass.
ml was added and stirred well. The number of bacteria in the washing solution was measured in the same manner as described above.

(4) Skin Roughness Test Each of the panelists was contacted with both hands for 5 minutes with the obtained disinfected wet tissue and then air-dried. This operation was repeated twice a day for one month. afterwards,
Self-reported skin condition. The number of panelists was 20.

Example 1 0.25% of ε-polylysine (manufactured by Chisso), and the fatty acid was C
1.0% of monoglycerin fatty acid ester of ₈ (manufactured by Taiyo Kagaku Co., Sunsoft No. 700P-2) and purified water 9
8.75% was blended to obtain 250 g of the impregnating liquid. On the other hand, a non-woven fabric of a copper ammonia cellulose fiber continuous filament was produced by a method for producing a regenerated cellulose non-woven fabric described in JP-B-52-6381. The obtained nonwoven fabric had a single yarn diameter of 1.5 d and a basis weight of 38 g / m ² .
250 g of the above impregnating liquid was impregnated into 100 g of the nonwoven fabric to obtain a sterilized wet tissue.

Example 2 A disinfected wet tissue was produced in the same manner as in Example 1 except that ε-polylysine was used instead of ε-polylysine and the hydrochloride of ε-polylysine was used at a polylysine concentration of 0.25%. . Example 3 In Example 1, as glycerin fatty acid ester,
Fatty acids were produced Isshu Te disinfecting wet in the same manner as in Example 1, except for using monoglycerol fatty acid esters of C ₁₀ (Taiyo Kagaku Co., Sunsoft No760) 1.0%. Example 4 In Example 1, as the glycerin fatty acid ester,
Fatty monoglycerol fatty acid esters of C ₁₂ (Taiyo Kagaku Co., Sunsoft No750) except that a 1.0% to prepare a sterilization wet tissue in the same manner as in Example 1.

Example 5 In Example 1, polylysine was 0.05% and the fatty acid was C.
_A disinfected wet tissue was produced in the same manner as in Example 1 except that an impregnating solution containing 0.2% of monoglycerin fatty acid ester of No. ₈ and 99.75% of purified water was used. Example 6 An impregnating liquid prepared by mixing 0.25% of ε-polylysine, 1.0% of monoglycerin fatty acid ester having a C ₈ fatty acid, 5% of propylene glycol and 93.75% of purified water in Example 1 was used. A sterilized wet tissue was produced in the same manner as in Example 1 except for the presence of the disinfected wet tissue. Example 7 A sterilized wet tissue was manufactured in the same manner as in Example 1 except that a polyolefin and rayon-blended cotton thermal bond and a mixing ratio of 50/50 were used as the nonwoven fabric.

Comparative Example 1 The procedure of Example 1 was repeated except that 0.005% of ε-polylysine, 1.0% of monoglycerin fatty acid ester having a fatty acid of C ₈ and 98.995% of purified water were used. A sterilized wet tissue was produced in the same manner as in Example 1. Comparative Example 2 Example 1 was the same as Example 1 except that 0.25% of ε-polylysine, 0.05% of a monoglycerin fatty acid ester having a C ₈ fatty acid and 99.7% of purified water were used. A sterilized wet tissue was produced in the same manner.

Comparative Example 3 Example 1 was repeated except that 0.25% of ε-polylysine, 7% of monoglycerin fatty acid ester having a fatty acid of C ₈ and 92.75% of purified water were used. A sterilized wet tissue was produced in the same manner as in Example 1. Comparative Example 4 Example 1 was the same as Example 1, except that 0.25% of ε-polylysine, 1.0% of diglycerin fatty acid ester having a fatty acid of C ₈ and 98.75% of purified water were used. A sterilized wet tissue was produced in the same manner.

Comparative Example 5 The procedure of Example 1 was repeated, except that 0.25% of ε-polylysine, 1.0% of triglycerin fatty acid ester having a fatty acid of C ₈ and 98.75% of purified water were used. A sterilized wet tissue was produced in the same manner as in Example 1. Comparative Example 6 A sterilized wet tissue was prepared in the same manner as in Example 1 except that an impregnating solution containing 0.30% of ethyl paraben, 1.0% of glycerin and 98.7% of purified water was used. Manufactured.

Comparative Example 7 In Example 1, 70% of ethanol, 0.30% of ethyl paraben, 1.0% of glycerin and 28.7 of purified water were used.
% Sterilized wet tissue was manufactured in the same manner as in Example 1 except that the impregnating liquid containing the acetic acid was used. Comparative Example 8 Example 1 was repeated except that an impregnating liquid containing 30% of ethanol, 0.50% of benzalkonium chloride, 0.30% of ethylparaben, 1.0% of glycerin and 68.2% of purified water was used. A sterilized wet tissue was manufactured in the same manner as in Example 1.

Comparative Example 9 A sterilized wet tissue was produced in the same manner as in Example 1, except that an aqueous solution containing 0.1% of chitosan lactate was used as the impregnating liquid. <Test Example> Measurement of antibacterial and antifungal properties, sterilization test, sterilization persistence test and skin roughness test were performed using the sterilized wet tissues obtained in Examples 1 to 7 and Comparative Examples 1 to 9. The results were shown in Tables 1 to 4, respectively.

[0038]

[Table 1]

[0039]

[Table 2]

[0040]

[Table 3]

[0041]

[Table 4]

From Tables 1 to 4, it can be seen that the antibacterial wet tissues obtained in Examples 1 to 7 of the present invention have good antibacterial and antifungal properties, disinfecting properties and disinfection persistence, and have problems such as rough skin. It was shown to be less. On the other hand, in Comparative Example 1 in which the blending amount of polylysine was small, although antifungal properties were recognized, antibacterial properties, eradication properties and eradication sustainability were not recognized. In Comparative Example 2 in which the blending amount of the monoglycerin fatty acid ester was small, antibacterial properties, eradication properties, and antibacterial properties were observed, but antifungal properties were not observed, and Comparative Example 3 in which the blending amount was large.
Although the antibacterial and antifungal properties, the bactericidal property and the bactericidal continuity were good, the evaluation of the softness by the panelists was unpopular because a slimy feeling remained after wiping. In Comparative Example 4 or Comparative Example 5 using a diglycerin fatty acid ester or a triglycerin fatty acid ester, antibacterial properties, bacteria elimination properties and bacteria elimination persistence were observed, but no antifungal properties were observed.

In Comparative Example 6 in which ethylparaben was used without using polylysine, antibacterial and antifungal properties were recognized, but no disinfecting property and no disinfection persistence were observed, and 70% ethanol was added. In Comparative Example 7, although antibacterial and antifungal properties and bactericidal properties were recognized, the bactericidal continuity was not recognized. There was a unique cold feeling. Further, in Comparative Example 8 in which the blending ratio of ethanol was set to 30% and benzalkonium chloride was blended to 0.50%, although antibacterial and antifungal properties, bactericidal properties and bactericidal continuity were recognized, the skin roughness test showed that the panelists did not. Rough skin occurs,
My skin turned red. Furthermore, in Comparative Example 9 using an aqueous solution containing chitosan lactate, antibacterial and antifungal properties were recognized, but no eradication property and eradication sustainability were observed.

[0044]

According to the antibacterial wet tissue of the present invention, since it uses polylysine as a natural component and glycerin fatty acid ester as a food additive, it has excellent antibacterial and antifungal properties and is a wet tissue. There is no risk of contamination by bacteria and fungi during storage. In addition, after the use of the wet tissue, not only can the wiped object be disinfected, but also the disinfection continuity can be imparted to the object to prevent subsequent recontamination by bacteria. Furthermore, since it is made of natural ingredients and food additives, it is harmless to the human body and can be safely cleaned even if it is put into the mouth. Therefore, the antibacterial wet tissue of the present invention is useful for cleaning the skin of the human body, cleaning personal belongings of babies and elderly people, cleaning living spaces such as kitchens and refrigerators, cleaning the skin for medical use and cleaning miscellaneous goods, foods, and the like. It can be preferably used for cleaning sanitary and food containers, and also as a wet tissue for directly wrapping food, in terms of hygiene and safety.

Continued on the front page (51) Int.Cl. ⁶ Identification code FI B32B 5/28 B32B 5/28 Z D06M 13/40 13/20

Claims (2)

[Claims] 1. A nonwoven fabric containing 10 to 100% by weight of cellulosic fibers is impregnated with an aqueous solution containing polylysine and / or a salt thereof and a glycerin fatty acid ester in a weight of 0.5 to 5 times the weight of the nonwoven fabric. Disinfection wet tissue characterized by having been made. 2. The aqueous solution contains 0.01 to 1 polylysine.
% By weight and glycerin fatty acid ester in the range of 0.1 to 5% by weight, and the polylysine is ε-polylysine, and the glycerin fatty acid ester is formed by reacting at least one fatty acid of caprylic acid, capric acid and lauric acid with glycerin. The disinfected wet tissue according to claim 1, which is a monoester.