JPH11113780A - Sterile wet tissue - Google Patents
Sterile wet tissueInfo
- Publication number
- JPH11113780A JPH11113780A JP9280398A JP28039897A JPH11113780A JP H11113780 A JPH11113780 A JP H11113780A JP 9280398 A JP9280398 A JP 9280398A JP 28039897 A JP28039897 A JP 28039897A JP H11113780 A JPH11113780 A JP H11113780A
- Authority
- JP
- Japan
- Prior art keywords
- fatty acid
- polylysine
- wet tissue
- acid ester
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cleaning Implements For Floors, Carpets, Furniture, Walls, And The Like (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Laminated Bodies (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は除菌ウェットティッ
シュに関し、さらに詳しくは優れた除菌性を有し、人体
に対して無害で肌に優しい皮膚清浄用、赤ちゃんや病人
の身の回り品の清浄用、台所や冷蔵庫、トイレ等の居住
空間の清浄用、食品や食品用の容器の清浄用、または果
物や野菜などを包む鮮度保持シ−トとして好適な除菌ウ
ェットティッシュに関するものである。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a disinfecting wet tissue, and more particularly, to an excellent disinfecting agent, harmless to the human body and harmless to the skin, and for cleaning personal belongings of babies and sick persons. The present invention relates to a disinfecting wet tissue suitable for cleaning living spaces such as kitchens, refrigerators and toilets, cleaning food and food containers, or as a freshness preserving sheet for wrapping fruits and vegetables.
【０００２】[0002]
【従来の技術】近年、生活様式の多様化から快適・衛生
思考の気運が高まり、特に人体や生活関連商品の抗菌性
や消臭性の要求が強くなっている。特に住空間の快適性
・密閉性が増した現代では冬でも適度な温度・湿度が保
たれるようになり、色々な細菌類やかび類が繁殖し易
く、その害も多発している。また近年増加している皮膚
疾患の一部は、こうした異常に繁殖した細菌が原因と考
えられる。2. Description of the Related Art In recent years, diversification of lifestyles has led to an increase in feelings of comfort and hygiene, and in particular, there has been a strong demand for antibacterial properties and deodorant properties of human bodies and lifestyle-related products. In particular, in modern times when the comfort and tightness of the living space have been increased, moderate temperatures and humidity can be maintained even in winter, and various bacteria and molds are easy to propagate, and the harm is occurring frequently. Some of the skin diseases that have been increasing in recent years are thought to be caused by such abnormally propagated bacteria.
【０００３】また医療機関やそれに準ずる機関で使用さ
れる商品、いわゆるメディカル関連商品にも抗菌や消臭
の要求が強まっている。例えば、医療機関で近年大きな
問題となっているのが抗生物質に対して耐性を持つ細菌
の出現である。これらは抵抗力が低下している人体に対
して敗血症や真菌症などを引き起こし、最悪の場合には
死に至らしめるまでになっている。さらに今後、老人問
題が社会問題として大きくクローズアップされると考え
られる。例えば在宅の寝たきり老人などは、床ずれや感
染症などによる異臭の発生によって悩まされており、こ
れらも異常に発生した細菌類によるものである。[0003] Also, there is an increasing demand for antibacterial and deodorizing products used in medical institutions and similar institutions, so-called medical-related products. For example, a major problem in medical institutions in recent years has been the emergence of bacteria that are resistant to antibiotics. These cause sepsis, mycosis, etc. in a human body with reduced resistance, and in the worst case, even lead to death. In the future, it is thought that the elderly problem will be greatly highlighted as a social problem. For example, bedridden elderly people at home are troubled by abnormal odors caused by bedsores, infectious diseases and the like, and these are also caused by abnormally occurring bacteria.
【０００４】従って、微生物の繁殖を抑えて衛生的で快
適な製品が切望されており、抗菌性を目的とした様々な
方法が提案されている。例えば、人体や生活用品を清浄
する方法として種々の方法が採用されており、ウェット
ティッシュの使用はその代表的な方法である。一般にウ
ェットティッシュは、水を主成分とする水溶液が不織布
などの布帛に含浸された状態で使用される。このような
ウェットティッシュで人体や日曜雑貨類を拭き取ること
により、これらの表面のゴミや汚れをより効率的に除く
ことができるため、衛生・快適性を向上させる商品とし
て有効利用されている。これらのウェットティッシュに
用いられている水溶液中には、保水性を保つ化合物、乾
燥性・腐敗性を防ぐための化合物、香料などが添加され
ている。[0004] Therefore, there is a long-felt need for hygienic and comfortable products that suppress the growth of microorganisms, and various methods for antibacterial properties have been proposed. For example, various methods have been adopted as a method for cleaning the human body and daily necessities, and the use of wet tissue is a typical method. Generally, a wet tissue is used in a state where an aqueous solution containing water as a main component is impregnated into a fabric such as a nonwoven fabric. By wiping the human body and sundry goods with such a wet tissue, dust and dirt on these surfaces can be more efficiently removed, and thus are effectively used as a product for improving hygiene and comfort. The aqueous solution used in these wet tissues contains a compound for maintaining water retention, a compound for preventing drying and spoilage, and a fragrance.
【０００５】しかしながら、上記のウェットティッシュ
には、汚れや埃を落とす清浄効果はあるが、その表面に
付いた細菌等を取り除く除菌効果は殆どなかった。この
ため、快適・衛生志向の高まりのなかで、除菌性を付与
するいろいろな方法が提案されている。例えば、エタノ
ールやイソプロパノール等のアルコール類を７０％前後
の高濃度に含有させた水溶液を用いたウェットティッシ
ュが提案されている（特開昭６４−２２８０４号公報、
特開平５−１５４６８号公報等）。しかし、高濃度のア
ルコール類を用いたウェットティッシュでは、アルコ−
ルの揮発性が高いために使用時に刺激臭がしたり、人体
に不快な冷感を与えたり、皮膚の油脂成分までふきとる
ことによる肌荒れを起こすという問題があった。またア
ルコ−ル類は拭いたときには除菌効果はあるが、それが
揮散してしまえば除菌性はなくなり、しばらくするとま
た細菌等に汚染されるという問題があった。[0005] However, the above-mentioned wet tissue has a cleaning effect of removing dirt and dust, but has almost no germicidal effect of removing bacteria and the like attached to the surface. For this reason, various methods for imparting disinfecting properties have been proposed with an increasing desire for comfort and hygiene. For example, a wet tissue using an aqueous solution containing an alcohol such as ethanol or isopropanol at a high concentration of about 70% has been proposed (JP-A-64-22804,
JP-A-5-15468). However, in a wet tissue using a high concentration of alcohol, alcohol-
Because of its high volatility, it has a problem that it gives off an irritating odor during use, gives an unpleasant cooling sensation to the human body, and causes rough skin by wiping even the oil and fat components of the skin. Further, alcohols have a disinfecting effect when wiped, but if they are volatilized, the disinfecting property is lost, and after a while, there is a problem that they are contaminated by bacteria and the like.
【０００６】これらを改良するため、一般の抗菌剤、例
えば、塩化ベンザルコニウム等の第４級アンモニウム
塩、パラオキシ安息香酸などの抗菌性のある化合物を含
む水溶液を含浸させたウェットティッシュが提案されて
いる（特開平３−１６５４２号公報、特開平６−４６９
６８号公報、実開昭６０−１６３９１４号公報）。しか
し、これらの化合物を抗菌剤として用いた場合には、高
濃度のアルコール類を使用したウェットティッシュと比
べると抗菌性が弱いため、細菌類を除菌するまでには至
っていない。またアルコール類と同程度の除菌効果を得
るために抗菌性能の高い材料を使用したり、添加量を増
したりすると、アルコール類以上に皮膚に対する刺激性
が強くなり、かゆみやかぶれの原因になるという問題が
あった。またウェットティッシュは、口の周りを拭いた
り、赤ちゃん用玩具、りんごやなしなどの果物、屋外で
使用する場合のスプーンや食器など直接口にする物の清
浄に使用されることが多いが、上記化合物は、人体に対
して安全レベルにある使用量に限られ、その経口毒性等
の点で衛生・安全上、好ましいものではなかった。[0006] In order to improve these, a wet tissue impregnated with an aqueous solution containing a general antibacterial agent, for example, a quaternary ammonium salt such as benzalkonium chloride, and an antibacterial compound such as paraoxybenzoic acid has been proposed. (JP-A-3-16542, JP-A-6-469)
No. 68, Japanese Utility Model Publication No. 60-163914). However, when these compounds are used as antibacterial agents, the antibacterial properties are weaker than wet tissues using high-concentration alcohols, so that bacteria have not been eliminated. Also, if a material with high antibacterial performance is used or the amount added is increased in order to obtain the same degree of bactericidal effect as alcohols, irritation to the skin becomes stronger than alcohols, causing itching and rash There was a problem. In addition, wet tissue is often used to wipe around the mouth, clean toys for babies, fruits such as apples and pears, and spoons and tableware for outdoor use such as direct cleaning. The compound is used only at a safe level for the human body, and is not preferable in terms of oral toxicity and the like in terms of hygiene and safety.
【０００７】またアルコール含有量を低減するために上
記化合物とアルコール類の混合液を含浸させたウェット
ティッシュが提案されている（特開平１−１４３８０８
号公報）。しかし、この場合もアルコ−ル類の濃度が低
いため、抗菌性能の高い化合物を用いたり、添加量を多
くする必要があり、人体に対して好ましいものではなか
った。さらに特に人体に対して安全性を考慮したウェッ
トティッシュが提案されている。例えば、特開昭６４−
２５８２１号公報には、キトサン塩を添加することが、
特開平３−２９６２３号公報にはお茶抽出物を添加して
消臭することが提案されている。しかし、これらの化合
物の除菌効果は弱いものであり、除菌用ウェットティッ
シュとは言い難いものであった。In order to reduce the alcohol content, a wet tissue impregnated with a mixture of the above compound and alcohol has been proposed (JP-A-1-143808).
No.). However, also in this case, since the concentration of alcohols is low, it is necessary to use a compound having high antibacterial performance or to increase the amount of addition, which is not preferable for the human body. Furthermore, a wet tissue considering the safety of the human body has been proposed. For example, Japanese Patent Application Laid-Open
No. 25821 discloses adding a chitosan salt,
Japanese Patent Application Laid-Open No. Hei 3-29623 proposes adding a tea extract to deodorize. However, the disinfection effect of these compounds was weak, and it was hard to say that it was a disinfection wet tissue.
【０００８】一方、ウェットティッシュとは別に、直接
体内に入る食品などの安全性を考慮し、各種の菌に対し
て有効に働く食品用保存剤や食品保存用エタノ−ル製剤
が提案されている。例えば、特開昭６２−５８９７５号
公報にはε−ポリリジンと低級脂肪酸モノグリセライド
等の希釈剤を配合した食品保存剤が、特開平３−１６８
０７５号公報にはエタノ−ルにポリリジンとグリセリン
中低級脂肪酸エステルを添加した食品保存用エタノール
製剤が示されている。On the other hand, in addition to wet tissues, food preservatives and food preservative ethanol preparations that effectively work against various bacteria have been proposed in consideration of the safety of foods directly entering the body. . For example, Japanese Unexamined Patent Publication (Kokai) No. 62-58975 discloses a food preservative containing a mixture of e-polylysine and a diluent such as lower fatty acid monoglyceride.
No. 075 discloses an ethanol preparation for food preservation in which polylysine and glycerin middle and lower fatty acid esters are added to ethanol.
【０００９】これらの製剤には、保存中に製剤自身に菌
が混入しないこと、および対象物に噴霧するか塗布する
かなどして付着させた状態の除菌する能力を有すること
が要求される。これに対してウェットティッシュには、
含浸している薬液自身に菌が混入しないことは当然のこ
とながら、ウェットティッシュ上にもカビが生えず、か
つティッシュで拭き取った際にテッシュから浸出した薬
液で除菌できることが要求される。このようにウェット
ティッシュの薬液は、ティッシュ上の菌による汚染防止
と、ティッシュにいったんは保持された薬液がティッシ
ュから浸出して対象物を除菌するという役割を果たすも
のであり、上記製剤の役割と異なるため、これらの製剤
をウェットティッシュ用の薬液としてそのまま用いるの
は困難であった。上記製剤を噴霧したり、塗布したりし
ただけでは、対象物に製剤が水滴となって付着したり、
はじいたりするため均一な付着ができず、除菌性が十分
に発揮されない場合があった。[0009] These preparations are required to be free of bacteria in the preparation itself during storage and to have the ability to disinfect the attached state by spraying or applying to the object. . On the other hand, for wet tissue,
As a matter of course, it is required that mold does not grow on the wet tissue and that it can be sterilized by the chemical leached from the tissue when wiped off with the tissue. As described above, the chemical solution of the wet tissue plays a role of preventing contamination by bacteria on the tissue, and that the chemical solution once retained in the tissue leaches out of the tissue to remove bacteria, and the role of the above-described preparation. Therefore, it was difficult to use these preparations as they were as chemicals for wet tissues. By spraying or applying the above formulation, the formulation adheres to the target as water droplets,
Due to repelling, uniform adhesion could not be achieved, and there was a case where the bactericidal property was not sufficiently exhibited.
【００１０】[0010]
【発明が解決しようとする課題】本発明は、上記従来技
術の問題点を解決し、アルコール類の使用をできる限り
抑え、除菌能力が高く、均一な除菌効果を得ることがで
き、またその除菌効果が長持ちし、長期に使用しても皮
膚等の肌あれを起こすことがなく、さらに経口しても問
題がなく安全性の高い抗菌ウェットティッシュを提供す
るものである。DISCLOSURE OF THE INVENTION The present invention solves the above-mentioned problems of the prior art, suppresses the use of alcohols as much as possible, has a high sterilization ability, and can obtain a uniform sterilization effect. The present invention provides an antibacterial wet tissue which has a long lasting effect on disinfection, does not cause skin roughening even when used for a long period of time, and has no problem even when taken orally and has high safety.
【００１１】[0011]
【課題を解決するための手段】本発明で特許請求される
発明は以下の通りである。 （１）セルロ−ス系繊維を１０〜１００重量％含む不織
布に、ポリリジンおよび／またはその塩とグリセリン脂
肪酸エステルとエタノ−ルとを含有する水溶液を、上記
不織布に対して０．５〜５倍重量含浸させたことを特徴
とする除菌ウェットティッシュ。 （２）上記水溶液は、ポリリジンを０．０１〜１重量
％、グリセリン脂肪酸エステルを０．１〜５重量％およ
びエタノ−ルを１〜５０重量％の範囲で含有し、かつポ
リリジンはε−ポリリジンであり、グリセリン脂肪酸エ
ステルはカプリル酸、カプリン酸およびラウリン酸の少
なくとも一つの脂肪酸とグリセリンとのモノエステルで
あることを特徴とする（１）記載の除菌ウェットティッ
シュ。The invention claimed in the present invention is as follows. (1) An aqueous solution containing polylysine and / or a salt thereof, a glycerin fatty acid ester, and ethanol is added to a nonwoven fabric containing 10 to 100% by weight of a cellulose fiber by 0.5 to 5 times the nonwoven fabric. A sanitizing wet tissue characterized by being impregnated by weight. (2) The aqueous solution contains 0.01 to 1% by weight of polylysine, 0.1 to 5% by weight of glycerin fatty acid ester and 1 to 50% by weight of ethanol, and polylysine is ε-polylysine. Wherein the glycerin fatty acid ester is a monoester of glycerin with at least one fatty acid of caprylic acid, capric acid, and lauric acid, and the disinfected wet tissue according to (1).
【００１２】[0012]
【発明の実施の形態】以下に本発明を詳細に説明する。
本発明に用いられる不織布は、天然繊維の綿、天然の素
材を化学的に溶解・再生した再生繊維のキュプラ繊維、
レーヨン繊維などのセルロース系繊維を１０〜１００重
量％、好ましくは５０〜１００重量％含有する。セルロ
−ス系繊維を１０重量％以上の範囲で含む不織布は、吸
水性に富み、水溶液の保液性に優れ、また対人用に用い
た場合の肌触り性に優れる。DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in detail.
The nonwoven fabric used in the present invention is a natural fiber cotton, a regenerated fiber obtained by chemically dissolving and regenerating a natural material, a cupra fiber,
It contains 10 to 100% by weight, preferably 50 to 100% by weight of cellulosic fibers such as rayon fibers. The nonwoven fabric containing the cellulose fiber in an amount of 10% by weight or more has excellent water absorbability, excellent liquid retaining property of an aqueous solution, and excellent touch when used for personal use.
【００１３】上記セルロース系繊維以外の繊維として
は、パルプや化学的に合成、紡糸された合成繊維、例え
ばアクリル繊維、ポリパラフェニレン繊維、ビニロン繊
維、ポリウレタン繊維、ポリ塩化ビニル繊維、ナイロン
６、ナイロン６６、ナイロン６１０等のポリアミド繊
維、ポリエチレンテレフタレート、ポリブチレンテレフ
タレートなどのポリエステル繊維、ポリエチレン、ポリ
プロピレンなどのポリオレフィン繊維等を１種または２
種以上を混合して用いることができる。特に極細繊維や
捲縮性繊維からなる不織布にセルロ−ス系繊維を積層し
たものは、繊維の表面積の大きさや空隙の大きさによっ
て高い清浄効果を発揮することができる。The fibers other than the above-mentioned cellulosic fibers include pulp and chemically synthesized and spun synthetic fibers such as acrylic fiber, polyparaphenylene fiber, vinylon fiber, polyurethane fiber, polyvinyl chloride fiber, nylon 6, nylon 66, polyamide fibers such as nylon 610, polyester fibers such as polyethylene terephthalate and polybutylene terephthalate, and polyolefin fibers such as polyethylene and polypropylene.
A mixture of more than one species can be used. In particular, those obtained by laminating cellulosic fibers on a nonwoven fabric made of ultrafine fibers or crimpable fibers can exhibit a high cleaning effect depending on the surface area of the fibers and the size of the voids.
【００１４】本発明に用いられるポリリジンは、例え
ば、特公昭５９−２０３５９号公報に記載の製造法、す
なわち、ストレプトマイセス属に属するポリリジン生産
菌であるストレプトマイセス・アルブラス・サブスピ−
シ−ズ・リジノポリメラスを培地に培養し、得られた培
養物からε−ポリリジンを分離し採取することによって
得られる。ポリリジンは、遊離の形でも用いることがで
きるが、塩酸、硫酸、リン酸などとの無機酸塩または酢
酸、プロピオン酸、フマル酸、リンゴ酸、クエン酸など
との有機酸塩の形で用いることもできる。The polylysine used in the present invention can be produced, for example, by the production method described in JP-B-59-20359, that is, Streptomyces albras subsp., A polylysine-producing bacterium belonging to the genus Streptomyces.
It can be obtained by culturing a seed lysinopolymeras in a medium, separating and collecting ε-polylysine from the obtained culture. Polylysine can be used in a free form, but it should be used in the form of an inorganic acid salt with hydrochloric acid, sulfuric acid, phosphoric acid, etc. or an organic acid salt with acetic acid, propionic acid, fumaric acid, malic acid, citric acid, etc. Can also.
【００１５】このようなポリリジンは、大腸菌、黄色ぶ
どう状球菌などの空中浮遊菌、皮膚常在菌、緑膿菌など
の床ずれ原因菌などに対する抗菌効果を発揮する。また
ポリリジンは、カビ類に対する抗カビ性はそれほど高く
はないが、後述するグリセリン脂肪酸エステルと併用す
ることで、その抗カビ性を補うことができる。ポリリジ
ンは、不織布に含浸する水溶液中に０．０１〜１重量％
の範囲で含有させるのが好ましく、より好ましくは０．
１〜０．５重量％である。使用量が０．０１重量％未満
では、その抗菌効果・抗カビ効果が十分に発揮されない
場合があり、また使用量が１重量％を超えても効果は向
上せず、不経済となる。Such a polylysine exhibits an antibacterial effect against airborne bacteria such as Escherichia coli and Staphylococcus aureus, bacteria resident on the skin, and bedsores such as Pseudomonas aeruginosa. Although polylysine does not have a very high antifungal property against molds, it can supplement the antifungal property by using it in combination with a glycerin fatty acid ester described later. Polylysine is 0.01 to 1% by weight in the aqueous solution impregnating the nonwoven fabric.
Is preferably contained in the range of, more preferably, 0.1.
1 to 0.5% by weight. If the amount used is less than 0.01% by weight, the antibacterial effect and the antifungal effect may not be sufficiently exhibited, and if the amount exceeds 1% by weight, the effect is not improved and it becomes uneconomical.
【００１６】本発明に用いられるグリセリン脂肪酸エス
テルは、グリセリンと直鎖脂肪酸とのエステルであり、
１種または２種以上を混合して用いることができる。直
鎖脂肪酸としては、炭素数８〜１２の脂肪酸が好まし
く、特にカプリル酸、カプリン酸、ラウリン酸が好まし
い。酢酸をはじめとする脂肪酸、特に炭素数１２以下の
脂肪酸は強い抗菌効果を有し、また脂肪酸特有の臭気と
刺激を柔らげることができるグリセリンとのエステルも
同様に強い抗菌効果を示す。グリセリンとのエステルと
しては、抗菌効果の点から、モノエステルを用いるのが
好ましい。ジエステルまたはトリエステルでは抗菌効果
を得ることができない場合がある。The glycerin fatty acid ester used in the present invention is an ester of glycerin and a linear fatty acid,
One type or a mixture of two or more types can be used. As the straight-chain fatty acid, a fatty acid having 8 to 12 carbon atoms is preferable, and caprylic acid, capric acid, and lauric acid are particularly preferable. Fatty acids such as acetic acid, particularly fatty acids having 12 or less carbon atoms have a strong antibacterial effect, and esters with glycerin, which can soften the odor and stimulus peculiar to the fatty acids, also show a strong antibacterial effect. As an ester with glycerin, a monoester is preferably used from the viewpoint of an antibacterial effect. Diesters or triesters may not be able to achieve the antibacterial effect.
【００１７】ウェットティッシュに用いる薬液は、水に
対して溶解しやすいこと、保存時に黒カビ、青カビなど
のカビ類がティッシュ上に繁殖するのを防ぐ抗カビ性
や、酵母・カビなどの真菌類に対する除菌性を有するこ
とが必要であり、この点を考慮すると炭素数８の脂肪酸
であるカプリル酸または炭素数１０の脂肪酸であるカプ
リン酸とのモノエステルが最も好ましい。またグリセリ
ン脂肪酸エステルの水に対する溶解安定性を向上させる
ために、ポリグリセリン脂肪酸エステルやプロピレング
リコールを添加することができる。グリセリン脂肪酸エ
ステルは、カビ類に対する抗カビ性とともに、大腸菌、
黄色ぶどう状球菌、緑膿菌などの細菌類に対しても抗菌
性を有し、ポリリジンの抗菌性を補うことができる。The chemical solution used for the wet tissue is easily soluble in water, has an antifungal property to prevent molds such as black mold and blue mold from growing on the tissue during storage, and has a property against fungi such as yeast and mold. It is necessary to have a disinfecting property, and in view of this point, a monoester with caprylic acid which is a fatty acid having 8 carbon atoms or capric acid which is a fatty acid having 10 carbon atoms is most preferable. In order to improve the solubility stability of the glycerin fatty acid ester in water, a polyglycerin fatty acid ester or propylene glycol can be added. Glycerin fatty acid esters, along with antifungal properties against molds, E. coli,
It has antibacterial properties against bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa, and can supplement the antibacterial properties of polylysine.
【００１８】グリセリン脂肪酸エステルの使用量は、水
溶液に対して０．１〜５重量％が好ましく、より好まし
くは０．２５〜３重量％である。使用量が０．１重量未
満では抗菌効果・抗カビ効果を十分に発揮できず、５重
量％を超えると水溶液にヌメリが出てウェットティッシ
ュとして使用した際の手触り感が低下する場合があり、
またコスト高となる。本発明に用いられるエタノール
は、ポリリジンやグリセリン脂肪酸エステルの抗菌・抗
カビ性を補う役割とグリセリン脂肪酸エステルの溶解安
定性を向上させる役割を有し、その使用量は、水溶液に
対して１〜５０重量％が好ましく、より好ましくは５〜
３０重量％である。エタノ−ルの使用量が１重量％未満
ではグリセリン脂肪酸エステルの溶解安定性が保存中に
不安定になる場合があり、また５０重量％を超えると使
用時の刺激臭が強すぎたり、皮膚の油脂成分を必要以上
に拭き取り肌荒れの原因となる場合がある。The amount of the glycerin fatty acid ester used is preferably 0.1 to 5% by weight, more preferably 0.25 to 3% by weight, based on the aqueous solution. If the amount used is less than 0.1% by weight, the antibacterial and antifungal effects cannot be sufficiently exerted. If the amount exceeds 5% by weight, the aqueous solution may become slimy and the touch feeling when used as a wet tissue may be reduced.
In addition, the cost increases. Ethanol used in the present invention has a role of supplementing the antibacterial and antifungal properties of polylysine and glycerin fatty acid ester and a role of improving the dissolution stability of glycerin fatty acid ester. % By weight, more preferably 5 to 5% by weight.
30% by weight. If the amount of ethanol used is less than 1% by weight, the dissolution stability of the glycerin fatty acid ester may become unstable during storage. If it exceeds 50% by weight, the irritating odor at the time of use may be too strong, Oil and fat components may be wiped out more than necessary, causing skin roughness.
【００１９】本発明に用いられる水溶液には、上記した
ポリリジン、グリセリン脂肪酸エステルおよびエタノー
ルに加え、竹抽出物、ヒノキチオ−ル、プロタミン、茶
抽出物、リゾチ−ム、キトサンなどを所望に応じて添加
してもよい。ただし、ポリリジンやグリセリン脂肪酸エ
ステルのように、人体に対して安全性が確認されたもの
であることが望ましい。またウェットティッシュ用薬液
に一般的に用いられている添加剤、例えば、グリセリ
ン、プロピレングリコ−ル、ポリエチレングリコ−ルな
どの保湿剤、デキストリンなどの可溶化剤、乳酸、乳酸
ナトリウム、リンゴ酸、クエン酸、酒石酸、コハク酸な
どのｐＨ調整剤、増粘剤、色素、酸化防止剤、界面活性
剤等を所望に応じて使用してもよい。この場合にも人体
に対して安全性が確保でき、また衛生上好ましい添加剤
を使用するのが望ましい。To the aqueous solution used in the present invention, in addition to the above-mentioned polylysine, glycerin fatty acid ester and ethanol, bamboo extract, hinoxyl, protamine, tea extract, lysozyme, chitosan, etc. are added as required. May be. However, it is desirable that the substance has been confirmed to be safe for the human body, such as polylysine and glycerin fatty acid ester. In addition, additives generally used in liquid chemicals for wet tissues, for example, humectants such as glycerin, propylene glycol and polyethylene glycol, solubilizing agents such as dextrin, lactic acid, sodium lactate, malic acid, citric acid A pH adjuster such as an acid, tartaric acid, and succinic acid, a thickener, a dye, an antioxidant, a surfactant and the like may be used as desired. Also in this case, it is desirable to use additives that can ensure safety for the human body and that are hygienic.
【００２０】ポリリジン、グリセリン脂肪酸エステルお
よびエタノ−ルを含有させた水溶液をティッシュ用不織
布に含浸する量は、ティッシュ用不織布の重量に対して
０．５〜５倍重量、好ましくは１〜３倍重量で使用され
る。含浸量が０．５倍重量未満では、水溶液が不織布に
均一に含浸することができず、また５倍重量を超える
と、使用時に水溶液が手に必要以上に付いたり、取り出
した際に下に滴り落ちたりして、取り扱い性が悪くな
る。The amount of the aqueous solution containing polylysine, glycerin fatty acid ester and ethanol to be impregnated into the nonwoven fabric for tissue is 0.5 to 5 times, preferably 1 to 3 times the weight of the nonwoven fabric for tissue. Used in. If the impregnation amount is less than 0.5 times the weight, the aqueous solution cannot uniformly impregnate the nonwoven fabric, and if it exceeds 5 times the weight, the aqueous solution may stick to the hand more than necessary at the time of use, or may fall down when taken out. Drip and the handling becomes poor.
【００２１】本発明の除菌ウェットティッシュは、ポリ
リジン、グリセリン脂肪酸エステルおよびエタノ−ルを
含有する水溶液を、公知の方法で上記特定の不織布に含
浸させることにより得ることができ、細菌類から真菌類
に至るまでの菌に対する除菌性に優れ、また人体や皮膚
に対して安全性の高いものである。すなわち、本発明の
除菌ウェットティッシュは、ポリリジンとグリセリン脂
肪酸エステルを含有しているため、保存時のティッシュ
上の細菌の繁殖を防止するとともに、人体や物品を拭き
取り、人体や物品上に存在する細菌類を物理的に取り去
ることによって発揮するワイピング効果と、拭き取った
部分に付着したウェットティッシュの水溶液が細菌類に
接触して発揮する抗菌効果とによって、人体や物品を均
一に除菌することができる。The disinfected wet tissue of the present invention can be obtained by impregnating an aqueous solution containing polylysine, a glycerin fatty acid ester and ethanol with the above-mentioned specific nonwoven fabric by a known method. It is excellent in eradication of bacteria up to and has high safety for human body and skin. That is, since the disinfecting wet tissue of the present invention contains polylysine and glycerin fatty acid ester, it prevents the growth of bacteria on the tissue during storage, wipes the human body and articles, and is present on the human body and articles. The wiping effect exerted by physically removing the bacteria and the antibacterial effect exerted by the aqueous solution of the wet tissue attached to the wiped part coming into contact with the bacteria can uniformly disinfect the human body and articles. it can.
【００２２】またポリリジンやグリセリン脂肪酸エステ
ルは、容易に空中に揮散するものではないので、拭き取
った後も人体や物品上に残って抗菌効果を発揮し、除菌
性が持続することとなる。すなわち、拭き取り除菌後に
再度細菌が付着しても抗菌作用が働き、細菌に再度汚染
されることがない。またポリリジンは細菌が生成するも
ので天然物系の食品添加剤として用いられており、さら
にグリセリン脂肪酸エステルやエタノ−ルも食品添加物
として認定されており、ともに多くの食品に使用され、
皮膚に対しての安全性も確認されている。Further, since polylysine and glycerin fatty acid ester do not easily volatilize in the air, they remain on the human body and articles even after wiping off, exhibit an antibacterial effect, and maintain sterilization. That is, even if the bacteria adhere again after the wiping and elimination, the antibacterial effect works and the bacteria are not contaminated again. Polylysine is produced by bacteria and used as a natural food additive.Furthermore, glycerin fatty acid esters and ethanol are also certified as food additives, and are used in many foods together.
Safety on the skin has also been confirmed.
【００２３】このため、本発明の除菌ウェットティッシ
ュは、除菌性が優れ、安全性も高いことから、手指やお
しり等の肌を拭く対人用の除菌ウェットティッシュとし
て、また赤ちゃんやお年寄りの身の回り品の清浄、キッ
チンやトイレまわりといった居住空間の清浄、屋外や屋
内で使用する食品容器や箸、スプーン等の清浄などの対
物用の除菌ウェットティッシュとして、さらに果物や野
菜などを包む鮮度保持シートとして、さらにまたメディ
カル用途としての医療機関や在宅看護等に使用される人
体清浄用や雑品等の清浄用など様々な用途の除菌ウェッ
トティッシュとして使用することができる。For this reason, the sanitizing wet tissue of the present invention is excellent in sanitizing properties and high in safety, so that it can be used as a personal sanitizing wet tissue for wiping skin such as fingers and buttocks, and for babies and the elderly. Purification of personal belongings, cleaning of living spaces such as kitchens and toilets, sterilization wet tissue for purposes such as cleaning of food containers, chopsticks, spoons etc. used outdoors and indoors, as well as freshness wrapping fruits and vegetables It can be used as a holding sheet and as a disinfecting wet tissue for various uses such as for cleaning the human body and for cleaning miscellaneous goods used in medical institutions and home nursing as medical uses.
【００２４】[0024]
【実施例】以下、本発明を実施例によりさらに詳細に説
明するが、本発明はこれらの例に限定されるものではな
い。なお、例中の％は、特に限定しない限り重量％を示
す。また例中の抗菌・抗カビ性、除菌性、除菌維持性お
よび肌あれ性の試験は下記に示す方法で行った。 （１）抗菌・抗カビ性に対する測定 試料の抗カビ性の試験はハロー法（ＪＩＳ Ｌ１９０２
−１９９０）に準拠して行った。すなわち、黒カビの保
存用のサブロー寒天培地（１０ｍｌ）に２週間生育した
黒カビ（ＩＦＯー４４１４）の試験管１本分の分生子を
菌糸と共に胞子分散剤（０．００５％ジオクチルスルホ
コハク酸）１０ｍｌに分散させ、滅菌脱脂綿で濾過し、
溶解して４５℃に保った１００ｍｌのサブロー寒天培地
に加え、シャ−レ１枚当り１０ｍｌ分注して平板培地を
作製した。EXAMPLES Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples. In addition,% in an example shows a weight% unless there is particular limitation. Further, the tests of antibacterial and antifungal properties, disinfecting properties, disinfection maintaining properties and skin roughness in the examples were carried out by the following methods. (1) Measurement of antibacterial and antifungal properties The test for antifungal properties of samples was carried out by the halo method (JIS L1902
-1990). That is, a conidia of one test tube of black mold (IFO-4414) grown on a Sabouraud agar medium (10 ml) for preservation of black mold was added together with mycelium to 10 ml of a spore dispersant (0.005% dioctylsulfosuccinic acid). Disperse, filter with sterile cotton wool,
The plate was dissolved and added to 100 ml of Sabouraud agar medium kept at 45 ° C., and 10 ml was dispensed per plate to prepare a plate medium.
【００２５】試料を２ｃｍ×２ｃｍの大きさに切り、作
製した培地の上におき、２５℃で７日間の培養を行っ
た。評価としては、試料の周囲に生育阻止帯（ハロ−）
の形成されたもの（−−）、試料上で菌の生育が認めら
れかったものを（−）、試料上にまで菌の生育の認めら
れたものを（＋）とした。菌濃度を測定するため、サブ
ロ−寒天培地に加えた菌液１ｍｌを０．００５％ジオク
チルスルホコハク酸溶液９ｍｌに加え、この操作を繰り
返して段階希釈し、各々の希釈液とサブロ−寒天培地と
を混釈して冷やし固めた後、２５℃で７日間培養して菌
数を測定した。The sample was cut into a size of 2 cm × 2 cm, placed on the prepared medium, and cultured at 25 ° C. for 7 days. As the evaluation, a growth inhibition zone (halo-) was placed around the sample.
(-), Those with no growth of bacteria on the sample (-), and those with growth of bacteria on the sample were (+). In order to measure the bacterial concentration, 1 ml of the bacterial solution added to the Sabouraud-agar medium was added to 9 ml of a 0.005% dioctylsulfosuccinic acid solution, and this operation was repeated to carry out serial dilutions. After the mixture was chilled and solidified, it was cultured at 25 ° C. for 7 days and the number of bacteria was measured.
【００２６】また同様に抗菌性の試験をハロー法にて評
価した。用いた菌は、緑膿菌（ＩＦＯ−３０８０）およ
び大腸菌（ＩＦＯー３３０１）であり、普通寒天培地に
菌濃度約１０6個／ｍｌとなるよう加え、シャ−レ１枚
当たり１０ｍｌ分注して平板培地とした。また、真菌と
してはカンジタ菌（Ｃａｎｄｉｄａ ａｌｂｉｃａｎ
ｓ；ＡＴＣＣ１４０５３）をサブロ−寒天培地に菌濃度
約１０6個／ｍｌとなるよう加え、シャ−レ１枚当たり
１０ｍｌ分注して平板培地とした。他の方法は上記と同
様にし、３７℃で２４時間培養して上記と同様の評価を
行なった。さらに菌濃度の測定も、生理食塩水で段階希
釈した菌液を用いて、緑膿菌、大腸菌は普通寒天培地
で、カンジダ菌はサブロ−寒天培地で混釈し、３７℃で
２４時間培養して測定した。Similarly, the test for antibacterial activity was evaluated by the halo method. The bacteria used were Pseudomonas aeruginosa (IFO-3080) and Escherichia coli (IFO-3301), which were added to a normal agar medium at a bacterial concentration of about 10 6 cells / ml, and 10 ml was dispensed per dish. To give a plate medium. As fungi, Candida albican (Candida albican)
s; ATCC14053) was added to a Sabouraud-agar medium to give a bacterial concentration of about 10 6 cells / ml, and 10 ml was dispensed per plate to obtain a plate medium. Other methods were the same as described above, and the cells were cultured at 37 ° C. for 24 hours and evaluated as above. In addition, the bacterial concentration was also measured using a bacterial solution serially diluted with physiological saline, and Pseudomonas aeruginosa and Escherichia coli were diluted with an ordinary agar medium, and Candida bacteria were diluted with a Saburo-agar medium and cultured at 37 ° C. for 24 hours. Measured.
【００２７】（２）除菌性試験 滅菌シャ−レに入れた滅菌スライドガラスに黄色ブドウ
状球菌（ＡＴＣＣ６５３８Ｐ）が約１０6個／ｍｌの菌
濃度となるような菌液を１ｍｌ塗布した。この上を試料
で拭き取り、スライドガラス上の残存菌を洗い出すた
め、生理食塩水＋界面活性剤ポリオキシエチレン（２
０）ソルビタンモノオレエ−ト（Ｔｗｅｅｎ８０等）
０．２％溶液を直ちに１０ｍｌ添加し、よく攪拌した。
ここから０．１ｍｌを普通寒天培地に塗抹し、３７℃で
２４時間培養して菌数を測定した。同時に拭き取った後
の試料上の菌数を測定するため、試料を滅菌したバイア
ル瓶の中に入れ、３７℃で０，６，２４時間培養し、上
記と同様の洗い出し液を添加して菌数を測定した。(2) Bactericidal test 1 ml of a bacterial solution such that the concentration of Staphylococcus aureus (ATCC 6538P) was about 10 6 cells / ml was applied to a sterilized slide glass placed in a sterile dish. This was wiped with a sample, and in order to wash out residual bacteria on the slide glass, physiological saline + surfactant polyoxyethylene (2
0) Sorbitan monooleate (Tween80 etc.)
Immediately, 10 ml of the 0.2% solution was added, followed by thorough stirring.
From this, 0.1 ml was spread on an ordinary agar medium and cultured at 37 ° C. for 24 hours to measure the number of bacteria. At the same time, in order to measure the number of bacteria on the sample after wiping, put the sample in a sterilized vial, incubate at 37 ° C. for 0.6, 24 hours, add the same washing solution as above, and count the bacteria. Was measured.
【００２８】（３）除菌持続性試験 滅菌シャ−レに入れた滅菌スライドガラスを試料で拭き
取り、シャ−レの蓋をずらして０，１，４，７，２４時
間と放置した。その後、黄色ブドウ状球菌（ＡＴＣＣ６
５３８Ｐ）が約１０5個／ｍｌの菌濃度となるような菌
液を０．１ｍｌスライドガラスに塗布した。１０分後に
スライドガラス上の残存菌を洗い出すため、生理食塩水
＋界面活性剤ポリオキシエチレン（２０）ソルビタンモ
ノオレエ−ト（Ｔｗｅｅｎ８０等）０．２％溶液を１０
ｍｌ添加し、よく攪拌した。上記と同様に洗い出し液中
の菌数を測定した。(3) Persistence test of sterilization The sterilized slide glass put in the sterilized dish was wiped with the sample, and the lid of the dish was shifted and left for 0, 1, 4, 7, and 24 hours. Thereafter, Staphylococcus aureus (ATCC6
538P) was applied to a 0.1 ml slide glass so as to have a bacterial concentration of about 10 5 cells / ml. After 10 minutes, a 0.2% solution of physiological saline + a surfactant polyoxyethylene (20) sorbitan monooleate (Tween 80 or the like) was added to the slide glass to wash out residual bacteria on the slide glass.
ml was added and stirred well. The number of bacteria in the washing solution was measured in the same manner as described above.
【００２９】（４）肌あれ性試験 得られた除菌ウェットティッシュでパネラー各人にそれ
ぞれ両手を５分間接触させた後、風乾した。この操作を
１日あたり２回の割合で１カ月間繰り返した。その後、
肌の状態を自己申告させた。パネラーの数は２０名とし
た。(4) Skin Roughness Test Each of the panelists was contacted with both hands for 5 minutes with the obtained disinfected wet tissue and then air-dried. This operation was repeated twice a day for one month. afterwards,
Self-reported skin condition. The number of panelists was 20.
【００３０】実施例１ ε−ポリリジン（チッソ社製）０．２５％、脂肪酸がＣ
8のモノグリセリン脂肪酸エステル（太陽化学社製、サ
ンソフトＮｏ７００Ｐ−２）１．０％、エタノ−ル３０
％および精製水６８．７５％を配合して含浸液２５０ｇ
を得た。一方、特公昭５２ー６３８１号に記載された再
生セルロース不織布製造法により、銅アンモニアセルロ
ース繊維連続フィラメントの不織布を作製した。得られ
た不織布は、単糸径１．５ｄよりなり、目付けは３８ｇ
／ｍ2であった。上記含浸液２５０ｇを不織布１００ｇ
に含浸させて除菌ウェットティッシュとした。Example 1 0.25% of ε-polylysine (manufactured by Chisso), and the fatty acid was C
1.0% of monoglycerin fatty acid ester of No. 8 (manufactured by Taiyo Kagaku Co., Sunsoft No. 700P-2), ethanol 30
% And 68.75% of purified water, and impregnation liquid 250g
I got On the other hand, a non-woven fabric of a copper ammonia cellulose fiber continuous filament was produced by a method for producing a regenerated cellulose non-woven fabric described in JP-B-52-6381. The obtained nonwoven fabric has a single yarn diameter of 1.5 d and a basis weight of 38 g.
/ M 2 . 250 g of the above impregnating liquid is used for 100 g of nonwoven fabric
To give a sterilized wet tissue.
【００３１】実施例２ 実施例１において、ε−ポリリジンの代わりにε−ポリ
リジンの塩酸塩をポリリジン濃度にして０．２５％使用
した以外は実施例１と同様にして除菌ウェットティッシ
ュを製造した。 実施例３ 実施例１において、グリセリン脂肪酸エステルとして、
脂肪酸がＣ10のモノグリセリン脂肪酸エステル（太陽化
学社製、サンソフトＮｏ７６０）１．０％を用いた以外
は実施例１と同様にして除菌ウェットてィッシュを製造
した。 実施例４ 実施例１において、グリセリン脂肪酸エステルとして、
脂肪酸がＣ12のモノグリセリン脂肪酸エステル（太陽化
学社製、サンソフトＮｏ７５０）１．０％を用いた以外
は実施例１と同様にして除菌ウェットティッシュを製造
した。Example 2 A disinfected wet tissue was produced in the same manner as in Example 1 except that ε-polylysine was used instead of ε-polylysine and the hydrochloride of ε-polylysine was used at a polylysine concentration of 0.25%. . Example 3 In Example 1, as glycerin fatty acid ester,
Fatty acids were produced Isshu Te disinfecting wet in the same manner as in Example 1, except for using monoglycerol fatty acid esters of C 10 (Taiyo Kagaku Co., Sunsoft No760) 1.0%. Example 4 In Example 1, as the glycerin fatty acid ester,
Fatty monoglycerol fatty acid esters of C 12 (Taiyo Kagaku Co., Sunsoft No750) except that a 1.0% to prepare a sterilization wet tissue in the same manner as in Example 1.
【００３２】実施例５ 実施例１において、ポリリジン０．０５％、脂肪酸がＣ
8のモノグリセリン脂肪酸エステル０．２％、エタノー
ル３０％および精製水６９．７５％を配合した含浸液を
用いた以外は実施例１と同様にして除菌ウェットティッ
シュを製造した。 実施例６ 実施例１において、ε−ポリリジン０．２５％、脂肪酸
がＣ8のモノグリセリン脂肪酸エステル１．０％、エタ
ノ−ル３０％、プロピレングリコ−ル５％および精製水
６３．７５％を配合した含浸液を用いた以外は実施例１
と同様にして除菌ウェットティッシュを製造した。 実施例７ 実施例１において、不織布として、ポリオレフィンとレ
ーヨン混綿サーマルボンド、混率５０／５０を用いた以
外が実施例１と同様にして除菌ウェットティッシュを製
造した。Example 5 In Example 1, polylysine was 0.05% and the fatty acid was C.
A disinfected wet tissue was produced in the same manner as in Example 1 except that an impregnating liquid containing 0.2% of monoglycerin fatty acid ester of No. 8 , 30% of ethanol and 69.75% of purified water was used. Example 6 Example 1, .epsilon.-polylysine 0.25%, monoglyceride fatty acid ester 1.0% fatty acids C 8, ethanol - le 30% propylene glycol - a 63.75% 5% and purified water Le Example 1 except that the compounded impregnating liquid was used.
A sterilized wet tissue was produced in the same manner as described above. Example 7 A sterilized wet tissue was manufactured in the same manner as in Example 1 except that a polyolefin and rayon-blended cotton thermal bond and a mixing ratio of 50/50 were used as the nonwoven fabric.
【００３３】比較例１ 実施例１において、ε−ポリリジン０．００５％、脂肪
酸がＣ8のモノグリセリン脂肪酸エステル１．０％、エ
タノ−ル３０％および精製水６８．９９５％を配合した
含浸液を用いた以外は実施例１と同様の方法で除菌ウェ
ットティッシュを製造した。 比較例２ 実施例１において、ε−ポリリジン０．２５％、脂肪酸
がＣ8のモノグリセリン脂肪酸エステル０．０５％、エ
タノ−ル３０％および精製水６９．７％を配合した含浸
液を用いた以外は実施例１と同様の方法で除菌ウェット
ティッシュを製造した。[0033] In Comparative Example 1 Example 1, .epsilon.-polylysine 0.005%, fatty acid monoglycerol fatty acid ester 1.0% C 8, ethanol - impregnation solution containing a combination of Le 30% and purified water 68.995% A sterilized wet tissue was produced in the same manner as in Example 1 except that was used. Comparative Example 2 In Example 1, an impregnating liquid containing 0.25% of ε-polylysine, 0.05% of monoglycerin fatty acid ester having a C 8 fatty acid, 30% of ethanol, and 69.7% of purified water was used. Except for the above, a sterilized wet tissue was manufactured in the same manner as in Example 1.
【００３４】比較例３ 実施例１において、ε−ポリリジン０．２５％、脂肪酸
がＣ8のモノグリセリン脂肪酸エステル７％、エタノ−
ル３０％および精製水６２．７５％を配合した含浸液を
用いた以外は実施例１と同様の方法で除菌ウェットティ
ッシュを製造した。 比較例４ 実施例１において、ε−ポリリジン０．２５％、脂肪酸
がＣ8のジグリセリン脂肪酸エステル１．０％、エタノ
−ル３０％および精製水６８．７５％を配合した含浸液
を用いた以外は実施例１と同様の方法で除菌ウェットテ
ィッシュを製造した。Comparative Example 3 In Example 1, 0.25% of ε-polylysine, 7% of monoglycerin fatty acid ester having a fatty acid of C 8 , and ethanol
A sterilized wet tissue was manufactured in the same manner as in Example 1 except that an impregnating solution containing 30% of purified water and 62.75% of purified water was used. Comparative Example 4 In Example 1, an impregnating liquid containing 0.25% of ε-polylysine, 1.0% of a diglycerin fatty acid ester having a C 8 fatty acid, 30% of ethanol, and 68.75% of purified water was used. Except for the above, a sterilized wet tissue was manufactured in the same manner as in Example 1.
【００３５】比較例５ 実施例１において、ε−ポリリジン０．２５％、脂肪酸
がＣ8のトリグリセリン脂肪酸エステル１．０％、エタ
ノ−ル３０％および精製水６８．７５％を配合した含浸
液を用いた以外は実施例１と同様の方法で除菌ウェット
ティッシュを製造した。 比較例６ 実施例１において、エチルパラベン０．３０％、グリセ
リン１．０％および精製水９８．７％を配合した含浸液
を用いた以外は実施例１と同様の方法で除菌ウェットテ
ィッシュを製造した。Comparative Example 5 An impregnating liquid prepared by mixing 0.25% of ε-polylysine, 1.0% of triglycerin fatty acid ester having a C 8 fatty acid, 30% of ethanol and 68.75% of purified water in Example 1. A sterilized wet tissue was produced in the same manner as in Example 1 except that was used. Comparative Example 6 A sterilized wet tissue was prepared in the same manner as in Example 1 except that an impregnating solution containing 0.30% of ethyl paraben, 1.0% of glycerin and 98.7% of purified water was used. Manufactured.
【００３６】比較例７ 実施例１において、エタノール７０％、エチルパラベン
０．３０％、グリセリン１．０％および精製水２８．７
％を配合した含浸液を用いた以外は実施例１と同様の方
法で除菌ウェットティッシュを製造した。 比較例８ 実施例１において、エタノール３０％、塩化ベンザルコ
ニウム０．５０％、エチルパラベン０．３０％、グリセ
リン１．０％および精製水６８．２％を配合した含浸液
を用いた以外は実施例１と同様の方法で除菌ウェットテ
ィッシュを製造した。Comparative Example 7 In Example 1, 70% of ethanol, 0.30% of ethyl paraben, 1.0% of glycerin and 28.7 of purified water were used.
% Sterilized wet tissue was manufactured in the same manner as in Example 1 except that the impregnating liquid containing the acetic acid was used. Comparative Example 8 Example 1 was repeated except that an impregnating liquid containing 30% of ethanol, 0.50% of benzalkonium chloride, 0.30% of ethylparaben, 1.0% of glycerin and 68.2% of purified water was used. A sterilized wet tissue was manufactured in the same manner as in Example 1.
【００３７】比較例９ 実施例１において、キトサン乳酸塩０．１％を含む水溶
液を含浸液として用いた以外は実施例１と同様の方法で
除菌ウェットティッシュを製造した。 ＜試験例＞実施例１〜７および比較例１〜９で得られた
除菌ウェットティッシュを用いて抗菌・抗カビ性に対す
る測定、除菌性試験、除菌持続性試験および肌あれ性試
験を行い、それらの結果をそれぞれ表１〜４に示した。Comparative Example 9 A sterilized wet tissue was produced in the same manner as in Example 1, except that an aqueous solution containing 0.1% of chitosan lactate was used as the impregnating liquid. <Test Example> Measurement of antibacterial and antifungal properties, sterilization test, sterilization persistence test and skin roughness test were performed using the sterilized wet tissues obtained in Examples 1 to 7 and Comparative Examples 1 to 9. The results were shown in Tables 1 to 4, respectively.
【００３８】[0038]
【表１】 [Table 1]
【００３９】[0039]
【表２】 [Table 2]
【００４０】[0040]
【表３】 [Table 3]
【００４１】[0041]
【表４】 [Table 4]
【００４２】表１〜４から、本発明の実施例１〜７で得
られた抗菌ウェットティッシュは、抗菌・抗カビ性、除
菌性および除菌持続性も良好で、肌あれ等の不具合も少
ないことが示された。一方、ポリリジンの配合量の少な
い比較例１では、抗カビ性は認められたものの、抗菌
性、除菌性および除菌持続性は認められなかった。また
モノグリセリン脂肪酸エステルの配合量の少ない比較例
２では、抗菌性、除菌性および除菌持続性は認められた
ものの、抗カビ性は認められず、配合量の多い比較例３
では、抗菌・抗カビ性、除菌性および除菌持続性は良好
であったが、パネラーによる肌触り性の評価は拭き取り
後にヌルヌルした感じが残り、不評であった。またジグ
リセリン脂肪酸エステルまたはトリグリセリン脂肪酸エ
ステルを使用した比較例４または比較例５では、抗菌
性、除菌性および除菌持続性は認められたが、抗カビ性
は認められなかった。From Tables 1 to 4, it can be seen that the antibacterial wet tissues obtained in Examples 1 to 7 of the present invention have good antibacterial and antifungal properties, disinfecting properties and disinfection persistence, and have problems such as rough skin. It was shown to be less. On the other hand, in Comparative Example 1 in which the blending amount of polylysine was small, although antifungal properties were recognized, antibacterial properties, eradication properties and eradication sustainability were not recognized. In Comparative Example 2 in which the blending amount of the monoglycerin fatty acid ester was small, antibacterial properties, eradication properties, and antibacterial properties were observed, but antifungal properties were not observed, and Comparative Example 3 in which the blending amount was large.
Although the antibacterial and antifungal properties, the bactericidal property and the bactericidal continuity were good, the evaluation of the softness by the panelists was unpopular because a slimy feeling remained after wiping. In Comparative Example 4 or Comparative Example 5 using a diglycerin fatty acid ester or a triglycerin fatty acid ester, antibacterial properties, bacteria elimination properties and bacteria elimination persistence were observed, but no antifungal properties were observed.
【００４３】またポリリジンを使用せずにエチルパラベ
ンを使用した比較例６では、抗菌・抗カビ性は認められ
たが、除菌性および除菌持続性は認められず、またエタ
ノールを７０％配合した比較例７では、抗菌・抗カビ性
および除菌性は認められたものの、除菌持続性は認めら
れず、肌荒れ試験ではパネラーに肌荒れが生じ、使用時
にアルコール臭がすると同時に、拭いた時点で特有の冷
感があった。さらにエタノールの配合を３０％にし、塩
化ベンザルコニウム０．５０％を配合した比較例８で
は、抗菌・抗カビ性、除菌性および除菌持続性は認めら
れたものの、肌荒れ試験ではパネラーに肌荒れが生じ、
肌が赤くなった。さらにキトサン乳酸塩を含む水溶液を
用いた比較例９では抗菌・抗カビ性は認められたもの
の、除菌性および除菌持続性は認められなかった。In Comparative Example 6 in which ethylparaben was used without using polylysine, antibacterial and antifungal properties were recognized, but no disinfecting property and no disinfection persistence were observed, and 70% ethanol was added. In Comparative Example 7, although antibacterial and antifungal properties and bactericidal properties were recognized, the bactericidal continuity was not recognized. There was a unique cold feeling. Further, in Comparative Example 8 in which the blending ratio of ethanol was set to 30% and benzalkonium chloride was blended to 0.50%, although antibacterial and antifungal properties, bactericidal properties and bactericidal continuity were recognized, the skin roughness test showed that the panelists did not. Rough skin occurs,
My skin turned red. Furthermore, in Comparative Example 9 using an aqueous solution containing chitosan lactate, antibacterial and antifungal properties were recognized, but no eradication property and eradication sustainability were observed.
【００４４】[0044]
【発明の効果】本発明の抗菌ウェットティッシュによれ
ば、天然成分であるポリリジンや、食品添加物であるグ
リセリン脂肪酸エステルを使用し、かつエタノ−ルを含
有しているため、優れた抗菌・抗カビ性を有し、ウェッ
トティッシュの保存時に細菌や真菌類に汚染される心配
がない。また、ウェットティッシュの使用後は、拭き取
った対象物を除菌するばかりか、該対象物に対してその
後の細菌による再汚染を防ぐ除菌持続性を付与すること
ができる。さらに天然成分や食品添加物からなるので、
人体に対して無害で、口に入れるようなものでも安心し
て清浄できる。従って、本発明の抗菌ウェットティッシ
ュは、人体に対する皮膚清浄用、赤ちゃんやお年寄りの
身の回り品の清浄用、台所、冷蔵庫等の生活空間の清浄
用、メディカル用の皮膚清浄用および雑品洗浄用、食品
や食品用の容器の清浄用として、さらには食品を直接包
むウェットティッシュとして、衛生・安全上の面で好ま
しく使用することができる。According to the antibacterial wet tissue of the present invention, polylysine which is a natural component and glycerin fatty acid ester which is a food additive are used, and ethanol is contained. It has mold properties and does not have to worry about contamination by bacteria and fungi when storing wet tissue. In addition, after the use of the wet tissue, not only can the wiped object be disinfected, but also the disinfection continuity can be imparted to the object to prevent subsequent recontamination by bacteria. In addition, because it consists of natural ingredients and food additives,
It is harmless to the human body and can be safely cleaned even if it is put into the mouth. Therefore, the antibacterial wet tissue of the present invention is useful for cleaning the skin of the human body, cleaning personal belongings of babies and the elderly, cleaning living spaces such as kitchens and refrigerators, cleaning medical skin and cleaning miscellaneous goods, It can be preferably used in cleaning hygiene and safety, for cleaning containers for foods, and as a wet tissue for directly wrapping foods.
───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.6 識別記号 ＦＩ Ｄ０６Ｍ 13/40 ──────────────────────────────────────────────────続 き Continued on front page (51) Int.Cl. 6 Identification code FI D06M 13/40
Claims (2)
む不織布に、ポリリジンおよび／またはその塩とグリセ
リン脂肪酸エステルとエタノ−ルとを含有する水溶液
を、上記不織布に対して０．５〜５倍重量含浸させたこ
とを特徴とする除菌ウェットティッシュ。An aqueous solution containing polylysine and / or a salt thereof, a glycerin fatty acid ester and ethanol is added to a nonwoven fabric containing 10 to 100% by weight of a cellulose fiber in an amount of 0.5 to 100 wt%. A disinfected wet tissue characterized by being impregnated by 5 times the weight.
重量％、グリセリン脂肪酸エステルを０．１〜５重量％
およびエタノ−ルを１〜５０重量％の範囲で含有し、か
つポリリジンはε−ポリリジンであり、グリセリン脂肪
酸エステルはカプリル酸、カプリン酸およびラウリン酸
の少なくとも一つの脂肪酸とグリセリンとのモノエステ
ルであることを特徴とする請求項１記載の除菌ウェット
ティッシュ。2. The aqueous solution contains 0.01 to 1 polylysine.
% By weight, 0.1 to 5% by weight of glycerin fatty acid ester
Glycerin fatty acid ester is a monoester of glycerin with at least one fatty acid of caprylic acid, capric acid and lauric acid. The disinfected wet tissue according to claim 1, characterized in that:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9280398A JPH11113780A (en) | 1997-10-14 | 1997-10-14 | Sterile wet tissue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9280398A JPH11113780A (en) | 1997-10-14 | 1997-10-14 | Sterile wet tissue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH11113780A true JPH11113780A (en) | 1999-04-27 |
Family
ID=17624480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9280398A Pending JPH11113780A (en) | 1997-10-14 | 1997-10-14 | Sterile wet tissue |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH11113780A (en) |
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| JP2001040273A (en) * | 1999-07-27 | 2001-02-13 | Chisso Corp | Antibacterial coating and antibacterial product |
| JP2001146681A (en) * | 1999-11-18 | 2001-05-29 | Kao Corp | Deodorizing agent for fiber product |
| WO2001092632A1 (en) * | 2000-05-30 | 2001-12-06 | Ajinomoto Co., Inc. | Fiber product having antibacterial and deodorant function |
| WO2001043549A3 (en) * | 1999-11-24 | 2002-05-30 | 3M Innovative Properties Co | Fruit, vegetable, and seed disinfectants |
| JP2003073694A (en) * | 2001-06-20 | 2003-03-12 | Chisso Corp | Chemical for wet wiper and wet wiper using the same |
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| JP2001000358A (en) * | 1999-06-21 | 2001-01-09 | Yoshihiro Kawakita | Wet tissue package |
| JP2001040273A (en) * | 1999-07-27 | 2001-02-13 | Chisso Corp | Antibacterial coating and antibacterial product |
| JP2001146681A (en) * | 1999-11-18 | 2001-05-29 | Kao Corp | Deodorizing agent for fiber product |
| WO2001043549A3 (en) * | 1999-11-24 | 2002-05-30 | 3M Innovative Properties Co | Fruit, vegetable, and seed disinfectants |
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