KR100275656B1 - 다형성의 클래스 ii mhc 동종펩타이드를 이용한 림프구 증식의 억제 및 면역관용의 유도 방법 - Google Patents
다형성의 클래스 ii mhc 동종펩타이드를 이용한 림프구 증식의 억제 및 면역관용의 유도 방법 Download PDFInfo
- Publication number
- KR100275656B1 KR100275656B1 KR1019940703715A KR19940703715A KR100275656B1 KR 100275656 B1 KR100275656 B1 KR 100275656B1 KR 1019940703715 A KR1019940703715 A KR 1019940703715A KR 19940703715 A KR19940703715 A KR 19940703715A KR 100275656 B1 KR100275656 B1 KR 100275656B1
- Authority
- KR
- South Korea
- Prior art keywords
- class
- mammal
- mammals
- major histocompatibility
- histocompatibility complex
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Transplantation (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US871,289 | 1978-01-23 | ||
US87128992A | 1992-04-20 | 1992-04-20 | |
US871289 | 1992-04-20 | ||
US96177992A | 1992-10-15 | 1992-10-15 | |
US961,779 | 1992-10-15 | ||
US961779 | 1992-10-15 | ||
US97773792A | 1992-11-13 | 1992-11-13 | |
US977,737 | 1992-11-13 | ||
US977737 | 1992-11-13 | ||
US027,127 | 1993-03-05 | ||
US08/027,127 US5593698A (en) | 1990-10-31 | 1993-03-05 | Suppression of proliferative response and induction of tolerance with polymorphic class II MHC allopeptides |
PCT/US1993/003708 WO1993020842A1 (en) | 1992-04-20 | 1993-04-20 | Suppression of proliferative response and induction of tolerance with polymorphic class ii mhc allopeptides |
US27127 | 1998-02-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR950701228A KR950701228A (ko) | 1995-03-23 |
KR100275656B1 true KR100275656B1 (ko) | 2000-12-15 |
Family
ID=27487557
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019940703715A KR100275656B1 (ko) | 1992-04-20 | 1993-04-20 | 다형성의 클래스 ii mhc 동종펩타이드를 이용한 림프구 증식의 억제 및 면역관용의 유도 방법 |
Country Status (13)
Country | Link |
---|---|
US (1) | US5593698A (de) |
EP (1) | EP0637249B1 (de) |
JP (1) | JPH07505892A (de) |
KR (1) | KR100275656B1 (de) |
AT (1) | ATE205400T1 (de) |
AU (1) | AU686101B2 (de) |
BR (1) | BR9306345A (de) |
CA (1) | CA2118502A1 (de) |
DE (1) | DE69330752D1 (de) |
HU (1) | HUT71310A (de) |
IL (1) | IL105472A (de) |
NO (1) | NO943967L (de) |
WO (1) | WO1993020842A1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL99699A (en) | 1990-10-10 | 2002-04-21 | Autoimmune Inc | Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes |
US6156306A (en) * | 1994-08-17 | 2000-12-05 | Albert Einstein College Of Medicine Of Yeshiva University | Pancreatic β-cells for allogeneic transplantation without immunosuppression |
GB9505784D0 (en) * | 1995-03-22 | 1995-05-10 | Lynxvale Ltd | Anti-tumour treatment |
US7361331B2 (en) * | 1996-10-18 | 2008-04-22 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food | Plant bioreactors |
US6617171B2 (en) * | 1998-02-27 | 2003-09-09 | The General Hospital Corporation | Methods for diagnosing and treating autoimmune disease |
US6599710B1 (en) | 1999-03-10 | 2003-07-29 | The General Hospital Corporation | Treatment of autoimmune disease |
CA2402489C (en) * | 2000-03-15 | 2011-11-01 | Advanced Research And Technology Institute | Oral tolerance induction by collagen to prevent allograft rejection |
US7348005B2 (en) * | 2000-03-15 | 2008-03-25 | Advanced Research And Technology Institute | Oral tolerance induction by collagen to prevent allograft rejection |
ES2292594T3 (es) | 2000-05-24 | 2008-03-16 | The Government Of The Usa As Represented By The Secretary Of Department Of Health And Human Services | E-selectina para tratar o prevenir accidentes cerebrovasculares. |
DK1311542T3 (da) * | 2000-08-21 | 2008-11-10 | Apitope Technology Bristol Ltd | Tolerogene peptider |
US7582313B2 (en) * | 2002-06-27 | 2009-09-01 | The General Hospital Corporation | Methods of organ regeneration using Hox 11-expressing pluripotent cells |
US7628988B2 (en) | 2002-06-27 | 2009-12-08 | The General Hospital Corporation | Methods and compositions for treating type 1 diabetes |
US20040229785A1 (en) * | 2002-11-15 | 2004-11-18 | Denise Faustman | Screening methods to identify treatments for autoimmune disease |
US20080102054A1 (en) * | 2005-01-18 | 2008-05-01 | Faustman Denise L | Compositions Containing Agm Cells And Methods Of Use Thereof |
GB0710529D0 (en) | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
WO2009022154A2 (en) | 2007-08-15 | 2009-02-19 | Circassia Limited | Peptide with multiple epitopes |
DK2953634T3 (da) | 2013-02-07 | 2021-08-30 | Massachusetts Gen Hospital | Fremgangsmåder til udvidelse eller udtømning af regulerende t-celler |
US10137181B2 (en) * | 2014-04-01 | 2018-11-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Isolated donor MHC-derived peptide and uses thereof |
WO2016187068A1 (en) | 2015-05-15 | 2016-11-24 | The General Hospital Corporation | Antagonistic anti-tumor necrosis factor receptor superfamily antibodies |
EP3355914B1 (de) | 2015-09-29 | 2024-03-06 | The General Hospital Corporation | Eine bcg-haltige zusammensetzung zur cholesterolsenkung. |
KR102410778B1 (ko) | 2016-05-13 | 2022-06-21 | 더 제너럴 하스피탈 코포레이션 | 길항성 항-종양 괴사 인자 수용체 슈퍼패밀리 항체 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5364762A (en) * | 1990-03-21 | 1994-11-15 | Board Of Trustees Of The Leland Stanford Junior University | Major histocompatibility complex (MHC) molecules |
-
1993
- 1993-03-05 US US08/027,127 patent/US5593698A/en not_active Expired - Fee Related
- 1993-04-20 CA CA002118502A patent/CA2118502A1/en not_active Abandoned
- 1993-04-20 EP EP93910671A patent/EP0637249B1/de not_active Expired - Lifetime
- 1993-04-20 HU HU9403006A patent/HUT71310A/hu unknown
- 1993-04-20 JP JP5518673A patent/JPH07505892A/ja not_active Ceased
- 1993-04-20 WO PCT/US1993/003708 patent/WO1993020842A1/en active IP Right Grant
- 1993-04-20 KR KR1019940703715A patent/KR100275656B1/ko not_active IP Right Cessation
- 1993-04-20 IL IL10547293A patent/IL105472A/en not_active IP Right Cessation
- 1993-04-20 AT AT93910671T patent/ATE205400T1/de not_active IP Right Cessation
- 1993-04-20 BR BR9306345A patent/BR9306345A/pt not_active Application Discontinuation
- 1993-04-20 DE DE69330752T patent/DE69330752D1/de not_active Expired - Lifetime
- 1993-04-20 AU AU41083/93A patent/AU686101B2/en not_active Ceased
-
1994
- 1994-10-19 NO NO943967A patent/NO943967L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU4108393A (en) | 1993-11-18 |
JPH07505892A (ja) | 1995-06-29 |
NO943967D0 (no) | 1994-10-19 |
ATE205400T1 (de) | 2001-09-15 |
IL105472A (en) | 1999-06-20 |
AU686101B2 (en) | 1998-02-05 |
DE69330752D1 (de) | 2001-10-18 |
KR950701228A (ko) | 1995-03-23 |
EP0637249A4 (de) | 1997-01-08 |
CA2118502A1 (en) | 1993-10-28 |
HU9403006D0 (en) | 1994-12-28 |
NO943967L (no) | 1994-10-19 |
IL105472A0 (en) | 1993-08-18 |
EP0637249A1 (de) | 1995-02-08 |
US5593698A (en) | 1997-01-14 |
HUT71310A (en) | 1995-11-28 |
BR9306345A (pt) | 1998-06-30 |
WO1993020842A1 (en) | 1993-10-28 |
EP0637249B1 (de) | 2001-09-12 |
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E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20050722 Year of fee payment: 6 |
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LAPS | Lapse due to unpaid annual fee |