KR100273823B1 - 5-치환된 사이토신 및 다른 4,5-이치환된 피리미딘-2(1h)-온의 제조방법 - Google Patents

5-치환된 사이토신 및 다른 4,5-이치환된 피리미딘-2(1h)-온의 제조방법 Download PDF

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Publication number
KR100273823B1
KR100273823B1 KR1019920021948A KR920021948A KR100273823B1 KR 100273823 B1 KR100273823 B1 KR 100273823B1 KR 1019920021948 A KR1019920021948 A KR 1019920021948A KR 920021948 A KR920021948 A KR 920021948A KR 100273823 B1 KR100273823 B1 KR 100273823B1
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South Korea
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substituted
ring
formula
nitrogen
compound
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Expired - Fee Related
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KR1019920021948A
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English (en)
Korean (ko)
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KR930010007A (ko
Inventor
게르하르트예흐네
Original Assignee
벡커, 바인
훽스트 악티엔게젤샤프트
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
KR1019920021948A 1991-11-23 1992-11-21 5-치환된 사이토신 및 다른 4,5-이치환된 피리미딘-2(1h)-온의 제조방법 Expired - Fee Related KR100273823B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4138585 1991-11-23
DEP4138585.3 1991-11-23

Publications (2)

Publication Number Publication Date
KR930010007A KR930010007A (ko) 1993-06-21
KR100273823B1 true KR100273823B1 (ko) 2000-12-15

Family

ID=6445453

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920021948A Expired - Fee Related KR100273823B1 (ko) 1991-11-23 1992-11-21 5-치환된 사이토신 및 다른 4,5-이치환된 피리미딘-2(1h)-온의 제조방법

Country Status (9)

Country Link
US (1) US5359067A (https=)
EP (1) EP0544210B1 (https=)
JP (1) JP3261181B2 (https=)
KR (1) KR100273823B1 (https=)
AT (1) ATE186300T1 (https=)
CA (1) CA2083436C (https=)
DE (1) DE59209762D1 (https=)
DK (1) DK0544210T3 (https=)
TW (1) TW225525B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6792700A (en) * 1999-08-20 2001-03-19 Research Foundation Of The State University Of New York, The 5-propynylpyrimidine derivatives as cytotoxic enzyme inhibitors
CN1302004C (zh) * 2003-08-22 2007-02-28 浙江海正药业股份有限公司 一种阿糖胞苷的制备方法
WO2020203896A1 (ja) 2019-03-29 2020-10-08 シスメックス株式会社 新規人工核酸、その製造方法及び用途
WO2020226889A1 (en) * 2019-05-07 2020-11-12 Wellstat Therapeutics Corporation Formulations of uridine triacetate in triacetin
CN116322706B (zh) 2020-09-25 2025-12-05 株式会社理真思 新人工核酸、其制造方法和用途
EP4458836A4 (en) 2021-12-27 2025-05-21 Riken Genesis Co., Ltd. Novel artificial nucleic acid, method for producing same, and use of same

Also Published As

Publication number Publication date
CA2083436A1 (en) 1993-05-24
EP0544210B1 (de) 1999-11-03
ATE186300T1 (de) 1999-11-15
DK0544210T3 (da) 2000-04-25
CA2083436C (en) 2004-05-11
US5359067A (en) 1994-10-25
TW225525B (https=) 1994-06-21
EP0544210A1 (de) 1993-06-02
JP3261181B2 (ja) 2002-02-25
DE59209762D1 (de) 1999-12-09
KR930010007A (ko) 1993-06-21
JPH05222034A (ja) 1993-08-31

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