KR0142433B1 - Drink for mollifying alcohol - Google Patents

Abstract

The present invention relates to a hangover relaxation drink composition, first, the juice of the immature ripe tangerine contains a large amount of vitamin C and organic acid, the sex is warm in the synergism It is tasteless and non-toxic. It lowers gas and food, eliminates redness and swelling, and removes foot and foot phosphorus. To extinguish the essence, sooth the pain, and record it as a medicine of liver and bile ducts, aroma component and bitter taste substance of immature tangerine peel Increases the secretion of gastric juice and acts as a fragrant odor that enhances the taste. The mechanism of action in the liver or stomach was found to be due to the flavonoid component, an active ingredient, and hesperetin-7-0-β-D-rutinoside, a glycoside of flavonoids, was combined with naringin. It contains a large amount in the skin, and the main active ingredient is their mechanism, and the root root is sweating, antipyretic, jinjing, jigal, haeju It is effective for the poison, sake, etc.The active ingredient is isoflavone (Disozen-7, 4-DihydroxyIsoflavone), Dizinin (Didzin; Daidzein-7-) which is a glycoside of pravonoid 0-β-D-Glucoside and Puerrain (Daidzin-8-C-β-Glucocide) are active ingredients, and Anomum-Xanthioides is a perennial herb, and the taste of Dongbogam sugar solution is He is sour, his nature is mild, heals abdominal pain, congestion and vomiting, and he is effective against food poisoning. The active ingredient is d-borneol, bornylyl, bornyle-acetate, linerol, which is a kind of d-camphor and terpenoid (linalool), renolidol (C ₁₅ H ₁₆ O), etc. The present invention is liposomes after extracting the immature tangerine, the extract of the roots, barn, so that the extract does not lose the active ingredient, auxiliary It is to provide a hangover relief drink composition and the like by adding an enzyme and an appropriate adjuvant improved drinking.

Description

[Name of invention]

Drink composition for relaxation of hangover

Detailed description of the invention

The present invention relates to a hangover relief drink composition. Among the compositions of the hangover relaxation beverage according to the present invention, first, premature citrus unshiupeel was adopted. The immature tangerine is a tangerine fruit that has an immature turquoise color of the tangerine fruit. It is a fruit collected in early summer. The tangerine tree is an evergreen tree with a height of 2-3m and branches are branched, the flowering period is May, the fruiting period is November, and the fruit is orange and orange, sweet and dried, and the fruit is used as a herbal medicine. It contains a large amount of C and organic acid.

In the bogam of the bogam, the sex is warm, the taste is bitter, and it is non-toxic, and the gas and the food are lowered, and the elimination and sanctification are eliminated. It is also a foot medicine, a medicine, a medicine, an extinction of an enemy, and a soothing pain. And it is recorded as a medicine of liver and bile ducts. (Agreement: Heo Jun -Namsandang. 1981.)

The fragrance and bitter taste of immature tangerine peels increase the amount of gastric juice secretion and stimulate the taste. The mechanism of action on the liver and stomach was found to be due to the active ingredient flanoids, and hesperetin-7-0-β-D-rutinoside, a glycoside of flavonoids, was identified as naringin and naringin. It is contained in a large amount in the skin and the main active ingredient is their mechanism. (Natural Chemistry: Ryu, Kyung-Soo et al.

In addition, the root is the root of the perennial Manchurian plant (pueraria Thunbergiana), the roots of which extend 10m in length, and are all piled up with yellowish brown thick hair, distributed in mountainous areas or marshland throughout the country. It is September-October and the roots are used as care products in spring and autumn.

On the other hand, the roots of Donggeumgam-tang liquid juice are sweating, fever, and jingyeong (鎭 痙 .jigal (止渴. 해) poisoning (酒 毒: cures thirst, headache, and stomachache from hangover.) -It is divided into liquid juice pieces and miscellaneous pieces in the upper part, and these active ingredients are isoflavones, glycosides of prabonoids, Daidzen-7,4-Dihydroxy Isoflavones, and diazines. Didzin; Daidzein-7-0-β-D-Glucoside) and Purerain (Daidzein-8-C-β-Glucocide). -1990.) These have been identified as major active ingredients.

The barn (, Anomum Xanthioides) is a perennial herb, 1.5m high, the roots are columnar, thin and small nodes, the nodes have membranous scales, brown, and the flowering period is from June to June. It is a grass belonging to the family, and it has a bitter taste in Dongbyeongbogam tang liquid, which is an upper bound, has a mild temper, moderates abdominal pain, congestion and vomiting, and is effective against food poisoning. To date, the active ingredient has been studied so far: d-camphor and terpenoids (d0 borneol), bornylyl, and carbonyl acetate (bornyletate). -acetate), linerool, linoliool (nerolidol (C ₁₅ H ₁₆ O)).

The present invention liposomes extracts so that there is no loss of the purified active ingredient extracted from the prabonoid component and the root and the barn of the immature tangerine, the mechanism of action as described above, and then added coenzyme and an appropriate adjuvant to improve the drinkability It is intended to provide a hangover relief drink composition.

As described above, even the herbal medicines having a useful mechanism of action are not purified and contain natural substances such as chlorophyll, unsaturated hydrocarbons, tannins, and macromolecules, and thus are not suitable for use as beverages. Because each of the active ingredients are individually, but the use of the individual alone does not respond well to the hangover relief, the present invention through the extraction process of the active ingredient of the immature citrus peel and the active ingredient extract of the roots, roots, barn These extracts are composed of the flavonoids of immature tangerines, and the active ingredients extracted from brown root and barn are mixed and maximized synergistic effect through co-enzyme preparation. Provide one beverage composition.

Extracted active ingredients from these three herbal medicines (immature tangerines, roots and barns) and the isoflavones of brown roots in the flavonoids of hesperidin and naringin of immature tangerines, which are the flavonoid glycosides The effective bioactive substance was obtained by mixing the active ingredient of Daedzein and Puerarin barn at the ratio of 4-8 g of immature tangerine, 2-4 g of root roots, 1-2 g of barn, per 1 liter of purified water. To prepare a beverage composition for hangover relief by adding and mixing the coenzyme vitamin (B _1. B _2. B _6. C) and auxiliary ingredients such as citric acid, L-sparagine, L-Aspatic Acid, glycine, sorbitol.

[Reference Example of Active Ingredient Extraction Method]

(1) fravonoids extraction from immature tangerine peel

① From the early spring to early summer, the immature fruit or fruit of the tangerine tree is collected and 4 pieces of large fruit are removed to remove the middle body.

② Remove the middle body and wash 1kg of dried immature tangerine with a particle size of 840㎛.

③ 1kg finely divided immature tangerine peeled in the ultrasonic extractor containing 5ℓ of purified water (frequency 30KHz, time required 60min).

④ Filter the filtered immature tangerine again with a second extraction (frequency 20khz, time required 60min) from the ultrasonic extractor with purified water 3ℓ.

⑤ Mix with primary extract and evaporate to 1000ml under reduced pressure. Add 1000ml of acetone, an organic solvent, and shake for 60-90min.

(6) Completely volatilize the organic solvent (acetone) (remove chlorophyll, unsaturated hydrocarbon, etc.) and evaporate to 500ml aqueous solution under reduced pressure.

⑦ Add purified water to the concentrated extract and dilute to 1000ml.

⑧ After adding 100g of activated carbon to the diluted solution as above, shake it for 90min to remove and remove tannins and other polymer materials on the activated carbon, filter out the activated carbon, and evaporate the purified liquid under reduced pressure. Obtain 25-29 g of the effective ingredient extract yield.

(2) Extracting active ingredient of root

① Wash Cut off 1kg of healthy roots.

② Extract 1 kg of fine roots from an ultrasonic extractor containing 5 L of purified water (frequency 20khz, duration 60 minutes).

③ Filtrate the extract and filter the remnant root again with an ultrasonic extractor containing 3 liters of purified water (second extraction) (same as frequency and time required for the first extraction).-Mix the primary extract and the secondary extract.

④ The mixed extract was evaporated under reduced pressure, and the total amount was added to 1000 ml aqueous solution to add 1220 ml of ethanol (diluted to 55% of ethanol and 45% of water), followed by shaking for 60 minutes, followed by evaporation under reduced pressure. And purified water is added to make 1000 ml.

(5) Add 100 g of activated carbon to 1000 ml of the aqueous solution taken and shake for 90 minutes.

⑥ After removing activated carbon, evaporate under reduced pressure to obtain 22-27g of root active ingredient.

(3) Extracting livestock ingredients

① Peel 1000g of mature barn taken from June to September.

② 1000g of the prepared barn is extracted in the ultrasonic extractor containing 5L of 70% ethanol (frequency 30khz, duration 60 minutes).

③ The extract is filtered and the remaining barn is extracted again in an ultrasonic extractor containing 3% of 70% ethanol (the same frequency and time required for the first extraction). The extracted aqueous solution is filtered.

④ Extract the filtered primary and secondary aqueous solution and evaporate under reduced pressure to blow off ethanol, and add purified water to make 1000ml.

(5) Add 100 g of activated carbon to the obtained extract 1000ml and shake for 90 minutes.

⑥ After shaking, remove activated carbon and filter by evaporation under reduced pressure to obtain 17-21g of effective ingredient yield.

Composition and Action of the Invention

[Examples of Hangover Relaxation Beverage Composition]

Fravonoid component of immature tangerine obtained in Reference Example. Root active ingredient. The active ingredient extract is added to the barn at 4-8g, 2-4g and 1-2g per liter of purified water, and various supplements are added to form a hangover-relieving drink. 0.4g of skin peel per 0.2ml of drink, 0.2g of root roots, 0.1g of barn, 0.01mg of coenzyme vitamin B ₁ , B ₂ , B ₆ , 0.075mg of vitamin C and 0.02g of citric acid, 0.02mg of L-asparagine, L-Aspastic Acid 0.02mg, glycine 50mg, sorbitol 50mg.

[Reference Mechanism of Alcohol on Human Body]

When alcohol enters the body, the following chemical reactions occur.

Ethanol (ethylalcohol) breaks down into acetaldehyde (causes hangover and damages liver and brain cells) first, followed by acetic acid, the intermediate of normal metabolism in the body. Headache, abdominal pain, vomiting, nausea or dizziness (眩暈) can also come.

[Effects of the Invention]

The composition enters the body by the following mechanisms to help the activity of human enzymes, promote the breakdown of alcohol and acetaldehyde (Acetaldehyde) in the body and inhibit the damage of alcohol and liver cells in the blood.

Hesperidin (a hesperedin glycoside Hesperedin-7 -β-D rutinocide), a flavonoid component of immature tangerines, Daidzein (7.4'-Dihydroxyisoflavone) glycoside of Isoflavone, an extract active ingredient of Naringin and brown root, Didzin (daidzein- 7-0-β-d-glucoside) and Puerarin (daidzein-8-c-β-d-glucoside) and di-camphor and terpenoids, which are effective extracts of barn Borneol (d-borneol), bornylyl (bornyl-acetate), linoleol (linalool), renal (neroli) and a series of coenzymes through the action of these enzymes enter the body By activating the enzyme, it promotes alcohol oxidation and reduces acetaldehyde, which prevents hangovers through mechanisms that produce carbon dioxide and releases it out of the body. Mechanism that allows Becoming.

Thus, the composition of the present invention is a flavonoid component of immature tangerine peel. The extract of active root and barn active ingredient is obtained from 4-8g, 2-4g, 1-2g of purified water per liter of purified water, and then the coenzyme and various supplements are added to improve the drinking performance. To make up.

Claims (1)

In the preparation of alcoholic hangover drink using the organic solvent and activated carbon extracted from purified immature tangerine, the flavonoids extracted from immature tangerine per 100 ml of purified water 0.4-0.8 g, brown root 0.2-0.4g, 0.1-0.2g barn, mix and add vitamin B ₁ 0.01mg, B ₂ 0.01mg, B ₆ 0.01mg, vitamin C 0.075mg, citric acid 0.02g, glycine 50mg, sorbitol 50mg, L- Asparagin 0.02mg, L-Aspatic Acid 0.02mg, The composition of the hangover for alcohol relaxation.