KE3737A - N-naphthoylglycine derivatives - Google Patents
N-naphthoylglycine derivativesInfo
- Publication number
- KE3737A KE3737A KE3737A KE373787A KE3737A KE 3737 A KE3737 A KE 3737A KE 3737 A KE3737 A KE 3737A KE 373787 A KE373787 A KE 373787A KE 3737 A KE3737 A KE 3737A
- Authority
- KE
- Kenya
- Prior art keywords
- derivatives
- hydrogen
- useful
- lower alkyl
- naphthoylglycine
- Prior art date
Links
- YQHPVWRRSORYIV-UHFFFAOYSA-N 2-(naphthalene-1-carbonylamino)acetic acid Chemical class C1=CC=C2C(C(=O)NCC(=O)O)=CC=CC2=C1 YQHPVWRRSORYIV-UHFFFAOYSA-N 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 102000016912 Aldehyde Reductase Human genes 0.000 abstract 1
- 108010053754 Aldehyde reductase Proteins 0.000 abstract 1
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- 206010012655 Diabetic complications Diseases 0.000 abstract 1
- 150000001323 aldoses Chemical class 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/68—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
- C07C63/72—Polycyclic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Seasonings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000372119A CA1176269A (en) | 1981-03-02 | 1981-03-02 | N-naphthoylglycine derivatives |
| CA000387991A CA1191156A (en) | 1981-10-15 | 1981-10-15 | N-((6-(lower alkoxy)-5-(trifluoromethylthio)-1- naphthalenyl)-thioxomethyl)-n-(lower alkyl)glycines |
| EP82300940A EP0059596B1 (en) | 1981-03-02 | 1982-02-24 | N-naphthoylglycine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KE3737A true KE3737A (en) | 1987-09-04 |
Family
ID=25669267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KE3737A KE3737A (en) | 1981-03-02 | 1987-07-07 | N-naphthoylglycine derivatives |
Country Status (18)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4446150A (en) * | 1982-09-21 | 1984-05-01 | Ayerst, Mckenna & Harrison, Inc. | Naphthalenylthiazole derivatives |
| FR2549474B1 (fr) * | 1983-07-19 | 1987-09-11 | Elf Aquitaine | Nouveaux thioamides, leurs preparation et applications |
| US4492706A (en) * | 1983-08-01 | 1985-01-08 | American Home Products Corporation | Method of lowering lipid levels |
| US4604406A (en) * | 1984-11-16 | 1986-08-05 | Ayerst, Mckenna & Harrison, Inc. | N-[6-methoxy-5-(perfluoroalkyl)-1-naphtholyl]-N-methylglycines and their thionaphthoyl analogs |
| US4663452A (en) * | 1985-08-29 | 1987-05-05 | Ethyl Corporation | Thiation process |
| US4734435A (en) * | 1986-04-07 | 1988-03-29 | American Home Products Corp. | N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxomethyl]-N-methylglycine S-oxide and the amide thereof |
| JPS63119455A (ja) * | 1986-06-27 | 1988-05-24 | Nippon Shinyaku Co Ltd | グリシン誘導体 |
| CA1307537C (en) * | 1987-12-23 | 1992-09-15 | Jay E. Wrobel | N-naphthoylglycines as aldose reductase inhibitors |
| US4820727A (en) * | 1987-12-23 | 1989-04-11 | American Home Products Corporation | N-acyl-N-naphthoylglycines as aldose reductase inhibitors |
| DE4318069C1 (de) * | 1993-06-01 | 1994-03-31 | Cassella Ag | Verfahren zur Herstellung von 5-Brom-6-methoxy-1-naphthoesäuremethylester |
| DE19603329A1 (de) | 1996-01-31 | 1997-08-07 | Bayer Ag | Verfahren zur Herstellung von aromatischen Methoxycarbonsäuremethylestern |
| WO1998042324A2 (en) * | 1997-03-21 | 1998-10-01 | The Regents Of The University Of California | Methods for modulating neurotrophic factor-associated activity using aldose reductase inhibitors |
| US6696407B1 (en) | 1997-03-21 | 2004-02-24 | The Regents Of The University Of California | Huntington's disease treatment comprising administering aldose reductase inhibitors to increase striatal CNTF |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
-
1982
- 1982-02-10 AU AU80342/82A patent/AU544067B2/en not_active Expired
- 1982-02-24 CY CY138582A patent/CY1385A/xx unknown
- 1982-02-24 EP EP82300940A patent/EP0059596B1/en not_active Expired
- 1982-02-24 DE DE8282300940T patent/DE3263225D1/de not_active Expired
- 1982-02-24 AT AT82300940T patent/ATE12932T1/de not_active IP Right Cessation
- 1982-02-25 PH PH26913A patent/PH17378A/en unknown
- 1982-03-01 IE IE448/82A patent/IE52604B1/en not_active IP Right Cessation
- 1982-03-01 DK DK089182A patent/DK160760C/da not_active IP Right Cessation
- 1982-03-01 ES ES510004A patent/ES510004A0/es active Granted
- 1982-03-01 HU HU82615A patent/HU188778B/hu unknown
- 1982-03-02 SU SU823462357A patent/SU1241985A3/ru active
- 1982-03-02 GR GR67447A patent/GR76037B/el unknown
-
1987
- 1987-05-15 SG SG44687A patent/SG44687G/en unknown
- 1987-06-05 DO DO1987004565A patent/DOP1987004565A/es unknown
- 1987-07-07 KE KE3737A patent/KE3737A/xx unknown
- 1987-10-29 HK HK809/87A patent/HK80987A/en not_active IP Right Cessation
- 1987-12-30 MY MY627/87A patent/MY8700627A/xx unknown
-
1994
- 1994-05-16 GE GEAP19941918A patent/GEP19960617B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES8307214A1 (es) | 1983-07-01 |
| EP0059596A1 (en) | 1982-09-08 |
| PH17378A (en) | 1984-08-06 |
| DK89182A (da) | 1982-09-03 |
| AU544067B2 (en) | 1985-05-16 |
| GEP19960617B (en) | 1996-12-12 |
| DE3263225D1 (de) | 1985-05-30 |
| ATE12932T1 (de) | 1985-05-15 |
| GR76037B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-08-03 |
| SU1241985A3 (ru) | 1986-06-30 |
| EP0059596B1 (en) | 1985-04-24 |
| IE52604B1 (en) | 1987-12-23 |
| AU8034282A (en) | 1982-09-09 |
| DK160760B (da) | 1991-04-15 |
| CY1385A (en) | 1987-12-18 |
| IE820448L (en) | 1982-09-02 |
| SG44687G (en) | 1987-07-24 |
| ES510004A0 (es) | 1983-07-01 |
| HU188778B (en) | 1986-05-28 |
| MY8700627A (en) | 1987-12-31 |
| HK80987A (en) | 1987-11-06 |
| DK160760C (da) | 1991-09-23 |
| DOP1987004565A (es) | 1997-10-28 |
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