JPWO2024228396A1 - - Google Patents
Info
- Publication number
- JPWO2024228396A1 JPWO2024228396A1 JP2025518161A JP2025518161A JPWO2024228396A1 JP WO2024228396 A1 JPWO2024228396 A1 JP WO2024228396A1 JP 2025518161 A JP2025518161 A JP 2025518161A JP 2025518161 A JP2025518161 A JP 2025518161A JP WO2024228396 A1 JPWO2024228396 A1 JP WO2024228396A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363499274P | 2023-05-01 | 2023-05-01 | |
| PCT/JP2024/016835 WO2024228396A1 (ja) | 2023-05-01 | 2024-05-01 | オリゴヌクレオチド合成用の高脂溶性ヌクレオチドビルディングブロックおよびこれを用いたオリゴヌクレオチドの合成 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2024228396A1 true JPWO2024228396A1 (https=) | 2024-11-07 |
| JPWO2024228396A5 JPWO2024228396A5 (https=) | 2026-02-02 |
Family
ID=93332921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025518161A Pending JPWO2024228396A1 (https=) | 2023-05-01 | 2024-05-01 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP4707286A1 (https=) |
| JP (1) | JPWO2024228396A1 (https=) |
| KR (1) | KR20260003278A (https=) |
| CN (1) | CN121464145A (https=) |
| WO (1) | WO2024228396A1 (https=) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5891684A (en) * | 1992-10-15 | 1999-04-06 | Ribozyme Pharmaceuticals, Inc. | Base-modified enzymatic nucleic acid |
| ATE245161T1 (de) * | 1995-05-26 | 2003-08-15 | Genta Inc | Verfahren zur synthese von phosphororganischen verbindungen |
| US20040033973A1 (en) * | 2002-08-16 | 2004-02-19 | Muthiah Manoharan | Compounds and oligomeric compounds comprising novel nucleobases |
| WO2005070859A1 (ja) | 2004-01-27 | 2005-08-04 | Takeshi Wada | フルオラス担体およびそれを用いたオリゴヌクレオチド誘導体の製造方法 |
| JP5901610B2 (ja) * | 2010-04-12 | 2016-04-13 | ソマロジック・インコーポレーテッド | ５位修飾ピリミジンとその使用 |
| EP2816053B1 (en) * | 2012-02-17 | 2021-03-24 | Ajinomoto Co., Inc. | Base-protected oligonucleotide |
| TWI729028B (zh) | 2015-11-17 | 2021-06-01 | 日商日產化學工業股份有限公司 | 寡核苷酸的製造方法 |
| US12139507B2 (en) | 2018-05-02 | 2024-11-12 | Natias Inc. | Segment for use in synthesis of oligonucleotide, method for producing the same, and method for synthesizing oligonucleotide using the same |
| JP7393807B2 (ja) | 2019-05-21 | 2023-12-07 | 株式会社ナティアス | オリゴヌクレオチド合成に用いるマルチフルオラスブロックマーおよびこれを用いたオリゴヌクレオチド合成方法 |
-
2024
- 2024-05-01 WO PCT/JP2024/016835 patent/WO2024228396A1/ja not_active Ceased
- 2024-05-01 JP JP2025518161A patent/JPWO2024228396A1/ja active Pending
- 2024-05-01 CN CN202480045211.9A patent/CN121464145A/zh active Pending
- 2024-05-01 KR KR1020257040241A patent/KR20260003278A/ko active Pending
- 2024-05-01 EP EP24800127.3A patent/EP4707286A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024228396A1 (ja) | 2024-11-07 |
| KR20260003278A (ko) | 2026-01-06 |
| EP4707286A1 (en) | 2026-03-11 |
| CN121464145A (zh) | 2026-02-03 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20251031 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20251031 |