JPWO2024185734A5 - - Google Patents

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Publication number
JPWO2024185734A5
JPWO2024185734A5 JP2025505323A JP2025505323A JPWO2024185734A5 JP WO2024185734 A5 JPWO2024185734 A5 JP WO2024185734A5 JP 2025505323 A JP2025505323 A JP 2025505323A JP 2025505323 A JP2025505323 A JP 2025505323A JP WO2024185734 A5 JPWO2024185734 A5 JP WO2024185734A5
Authority
JP
Japan
Prior art keywords
nucleoside
och
formula
chloride
diphosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025505323A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2024185734A1 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2024/007991 external-priority patent/WO2024185734A1/ja
Publication of JPWO2024185734A1 publication Critical patent/JPWO2024185734A1/ja
Publication of JPWO2024185734A5 publication Critical patent/JPWO2024185734A5/ja
Pending legal-status Critical Current

Links

JP2025505323A 2023-03-03 2024-03-04 Pending JPWO2024185734A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363488207P 2023-03-03 2023-03-03
PCT/JP2024/007991 WO2024185734A1 (ja) 2023-03-03 2024-03-04 ポリリン酸化ヌクレオシド、ポリリン酸化ヌクレオシドの合成に用いられるリン酸部活性化ヌクレオチド及びその合成方法、ならびにリン酸部活性化ヌクレオチドを用いたポリリン酸化ヌクレオシドの合成方法

Publications (2)

Publication Number Publication Date
JPWO2024185734A1 JPWO2024185734A1 (https=) 2024-09-12
JPWO2024185734A5 true JPWO2024185734A5 (https=) 2025-11-17

Family

ID=92675140

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025505323A Pending JPWO2024185734A1 (https=) 2023-03-03 2024-03-04

Country Status (5)

Country Link
EP (1) EP4667479A1 (https=)
JP (1) JPWO2024185734A1 (https=)
KR (1) KR20250157528A (https=)
CN (1) CN120813591A (https=)
WO (1) WO2024185734A1 (https=)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872710B2 (en) * 1997-07-25 2005-03-29 Inspire Pharmaceuticals, Inc. Di(uridine 5′)-tetraphosphate and salts thereof
US7074596B2 (en) * 2002-03-25 2006-07-11 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Synthesis and use of anti-reverse mRNA cap analogues
CN101495497B (zh) 2006-07-26 2012-03-14 Yamasa酱油株式会社 二(嘧啶核苷5’-)多磷酸的制备方法
EP2049665A2 (en) * 2006-07-28 2009-04-22 Applera Corporation Dinucleotide mrna cap analogs
DK2940030T3 (en) 2012-12-28 2017-07-24 Yamasa Corp METHOD OF PREPARING P1, P4-DI (URIDIN 5 '-) TETRAPHOSPHATE
ES2964690T3 (es) 2015-09-21 2024-04-09 Trilink Biotechnologies Llc Método para sintetizar ARN con caperuza 5'
ES2983060T3 (es) * 2017-08-18 2024-10-21 Modernatx Inc Variantes de ARN polimerasa
WO2022212442A1 (en) 2021-03-31 2022-10-06 Modernatx, Inc. Synthesis of trinucleotide and tetranucleotide caps for mrna production
CN118978560A (zh) * 2021-08-27 2024-11-19 上海兆维科技发展有限公司 一种加帽类似物及其应用
CN113957108B (zh) * 2021-09-09 2025-01-10 上海兆维科技发展有限公司 一种加帽rna的合成方法以及加帽rna转录反应液
CN114941018B (zh) * 2022-06-28 2023-09-22 翌圣生物科技(上海)股份有限公司 cap1帽类似物的合成方法

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