JPWO2023116607A5 - - Google Patents

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Publication number
JPWO2023116607A5
JPWO2023116607A5 JP2024533904A JP2024533904A JPWO2023116607A5 JP WO2023116607 A5 JPWO2023116607 A5 JP WO2023116607A5 JP 2024533904 A JP2024533904 A JP 2024533904A JP 2024533904 A JP2024533904 A JP 2024533904A JP WO2023116607 A5 JPWO2023116607 A5 JP WO2023116607A5
Authority
JP
Japan
Prior art keywords
nucleotide sequence
nucleotide
seq
sirna
nucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024533904A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024546667A (ja
JP2024546667A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/139942 external-priority patent/WO2023116607A1/zh
Publication of JP2024546667A publication Critical patent/JP2024546667A/ja
Publication of JPWO2023116607A5 publication Critical patent/JPWO2023116607A5/ja
Publication of JP2024546667A5 publication Critical patent/JP2024546667A5/ja
Pending legal-status Critical Current

Links

JP2024533904A 2021-12-21 2022-12-19 核酸、当該核酸を含む組成物及び複合体並びに調製方法と使用 Pending JP2024546667A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202111575800 2021-12-21
CN202111575800.2 2021-12-21
PCT/CN2022/139942 WO2023116607A1 (zh) 2021-12-21 2022-12-19 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途

Publications (3)

Publication Number Publication Date
JP2024546667A JP2024546667A (ja) 2024-12-26
JPWO2023116607A5 true JPWO2023116607A5 (https=) 2025-12-24
JP2024546667A5 JP2024546667A5 (https=) 2025-12-24

Family

ID=86901326

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024533904A Pending JP2024546667A (ja) 2021-12-21 2022-12-19 核酸、当該核酸を含む組成物及び複合体並びに調製方法と使用

Country Status (8)

Country Link
US (1) US20250057870A1 (https=)
EP (1) EP4455284A1 (https=)
JP (1) JP2024546667A (https=)
KR (1) KR20240117104A (https=)
CN (1) CN118202049A (https=)
AU (1) AU2022422864A1 (https=)
CA (1) CA3242059A1 (https=)
WO (1) WO2023116607A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020280438B2 (en) 2019-05-22 2025-03-06 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
JP7610268B2 (ja) 2019-05-22 2025-01-08 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、薬物組成物及び複合体ならびに調製方法と使用
WO2020233680A1 (zh) 2019-05-22 2020-11-26 苏州瑞博生物技术股份有限公司 核酸、药物组合物与缀合物及制备方法和用途
EP3978609A4 (en) 2019-05-24 2024-02-07 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
CN121780524A (zh) * 2024-08-02 2026-04-03 北京尧景基因技术有限公司 抑制MAPT基因表达的siRNA及其缀合物和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009143371A2 (en) * 2008-05-21 2009-11-26 Intradigm Corporation COMPOSITIONS COMPRISING mTOR SIRNA AND METHODS OF USE THEREOF
WO2010064851A2 (ko) * 2008-12-02 2010-06-10 울산대학교 산학협력단 종간 교차활성을 지닌 mTOR을 표적으로 하는 siRNA, 이를 포함하는 재조합벡터 및 이를 함유하는 약학조성물
US20120136073A1 (en) 2010-11-15 2012-05-31 Life Technologies Corporation Amine-Containing Transfection Reagents and methods for making and using same
WO2017151732A1 (en) * 2016-03-02 2017-09-08 Beth Israel Deaconess Medical Center Technology Venture Office, Br2 Therapeutic targets for lin-28-expressing cancers
AU2018216509B2 (en) * 2017-01-31 2024-02-29 Curigin Co.,Ltd. Nucleic acid simultaneously inhibiting expression of mTOR gene and STAT3 gene
TN2019000308A1 (en) 2017-07-06 2021-05-07 Arrowhead Pharmaceuticals Inc RNAi AGENTS FOR INHIBITING EXPRESSION OF ALPHA-ENaC AND METHODS OF USE
WO2019105437A1 (zh) 2017-12-01 2019-06-06 苏州瑞博生物技术有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
EP3732185B1 (en) 2017-12-29 2025-02-26 Suzhou Ribo Life Science Co., Ltd. Conjugates and preparation and use thereof
WO2019217459A1 (en) 2018-05-07 2019-11-14 Alnylam Pharmaceuticals, Inc. Extrahepatic delivery
WO2020018461A1 (en) * 2018-07-16 2020-01-23 The University Of Virginia Patent Foundation Compositions and methods of diagnosis and treatment for neurological diseases
CN112423795A (zh) * 2018-12-28 2021-02-26 苏州瑞博生物技术股份有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途

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