JPWO2023105898A5 - - Google Patents

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Publication number
JPWO2023105898A5
JPWO2023105898A5 JP2023510304A JP2023510304A JPWO2023105898A5 JP WO2023105898 A5 JPWO2023105898 A5 JP WO2023105898A5 JP 2023510304 A JP2023510304 A JP 2023510304A JP 2023510304 A JP2023510304 A JP 2023510304A JP WO2023105898 A5 JPWO2023105898 A5 JP WO2023105898A5
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JP
Japan
Prior art keywords
antisense oligonucleotide
complementary strand
complex according
length
antisense
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2023510304A
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English (en)
Japanese (ja)
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JP7412668B2 (ja
JPWO2023105898A1 (enExample
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Priority claimed from PCT/JP2022/036699 external-priority patent/WO2023105898A1/ja
Publication of JPWO2023105898A1 publication Critical patent/JPWO2023105898A1/ja
Publication of JPWO2023105898A5 publication Critical patent/JPWO2023105898A5/ja
Priority to JP2023200811A priority Critical patent/JP2024015491A/ja
Application granted granted Critical
Publication of JP7412668B2 publication Critical patent/JP7412668B2/ja
Active legal-status Critical Current
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JP2023510304A 2021-12-07 2022-09-30 アンチセンスオリゴヌクレオチド複合体 Active JP7412668B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023200811A JP2024015491A (ja) 2021-12-07 2023-11-28 アンチセンスオリゴヌクレオチド複合体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021198890 2021-12-07
JP2021198890 2021-12-07
PCT/JP2022/036699 WO2023105898A1 (ja) 2021-12-07 2022-09-30 アンチセンスオリゴヌクレオチド複合体

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023200811A Division JP2024015491A (ja) 2021-12-07 2023-11-28 アンチセンスオリゴヌクレオチド複合体

Publications (3)

Publication Number Publication Date
JPWO2023105898A1 JPWO2023105898A1 (enExample) 2023-06-15
JPWO2023105898A5 true JPWO2023105898A5 (enExample) 2023-11-09
JP7412668B2 JP7412668B2 (ja) 2024-01-15

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ID=86730115

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023510304A Active JP7412668B2 (ja) 2021-12-07 2022-09-30 アンチセンスオリゴヌクレオチド複合体
JP2023200811A Pending JP2024015491A (ja) 2021-12-07 2023-11-28 アンチセンスオリゴヌクレオチド複合体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023200811A Pending JP2024015491A (ja) 2021-12-07 2023-11-28 アンチセンスオリゴヌクレオチド複合体

Country Status (5)

Country Link
US (1) US20250297249A1 (enExample)
EP (1) EP4446414A4 (enExample)
JP (2) JP7412668B2 (enExample)
CN (1) CN118660965A (enExample)
WO (1) WO2023105898A1 (enExample)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013089283A1 (en) * 2011-12-16 2013-06-20 National University Corporation Tokyo Medical And Dental University Chimeric double-stranded nucleic acid
AU2014272526A1 (en) * 2013-05-30 2015-12-10 National University Corporation Tokyo Medical And Dental University Double-stranded agents for delivering therapeutic oligonucleotides
CA2915443A1 (en) * 2013-06-16 2014-12-24 National University Corporation Tokyo Medical And Dental University Double-stranded antisense nucleic acid with exon-skipping effect
WO2016161388A1 (en) * 2015-04-03 2016-10-06 University Of Massachusetts Fully stabilized asymmetric sirna
EP3571300A1 (en) * 2017-01-19 2019-11-27 ProQR Therapeutics II B.V. Oligonucleotide complexes for use in rna editing
CN110799647A (zh) * 2017-06-23 2020-02-14 马萨诸塞大学 双尾自递送sirna及相关的方法
JP7333079B2 (ja) * 2018-03-19 2023-08-24 国立大学法人 東京医科歯科大学 毒性が軽減した核酸

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