JPWO2023086864A5 - - Google Patents

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Publication number
JPWO2023086864A5
JPWO2023086864A5 JP2024527763A JP2024527763A JPWO2023086864A5 JP WO2023086864 A5 JPWO2023086864 A5 JP WO2023086864A5 JP 2024527763 A JP2024527763 A JP 2024527763A JP 2024527763 A JP2024527763 A JP 2024527763A JP WO2023086864 A5 JPWO2023086864 A5 JP WO2023086864A5
Authority
JP
Japan
Prior art keywords
conjugate
oligonucleotide
tfr1
optionally
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024527763A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024546436A5 (https=
JP2024546436A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/079604 external-priority patent/WO2023086864A1/en
Publication of JP2024546436A publication Critical patent/JP2024546436A/ja
Publication of JP2024546436A5 publication Critical patent/JP2024546436A5/ja
Publication of JPWO2023086864A5 publication Critical patent/JPWO2023086864A5/ja
Pending legal-status Critical Current

Links

JP2024527763A 2021-11-12 2022-11-10 顔面肩甲上腕筋ジストロフィーを処置するための筋標的化複合体およびそれらの使用 Pending JP2024546436A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202163278993P 2021-11-12 2021-11-12
US202163278882P 2021-11-12 2021-11-12
US63/278,993 2021-11-12
US63/278,882 2021-11-12
US202263312633P 2022-02-22 2022-02-22
US202263312617P 2022-02-22 2022-02-22
US63/312,633 2022-02-22
US63/312,617 2022-02-22
PCT/US2022/079604 WO2023086864A1 (en) 2021-11-12 2022-11-10 Muscle targeting complexes for treating facioscapulohumeral muscular dystrophy

Publications (3)

Publication Number Publication Date
JP2024546436A JP2024546436A (ja) 2024-12-24
JP2024546436A5 JP2024546436A5 (https=) 2025-11-18
JPWO2023086864A5 true JPWO2023086864A5 (https=) 2025-11-18

Family

ID=86336621

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024527763A Pending JP2024546436A (ja) 2021-11-12 2022-11-10 顔面肩甲上腕筋ジストロフィーを処置するための筋標的化複合体およびそれらの使用

Country Status (7)

Country Link
US (1) US20250025570A1 (https=)
EP (1) EP4429711A1 (https=)
JP (1) JP2024546436A (https=)
KR (1) KR20240099448A (https=)
CA (1) CA3234136A1 (https=)
IL (1) IL312170A (https=)
WO (1) WO2023086864A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
EP3829595A4 (en) 2018-08-02 2022-08-24 Dyne Therapeutics, Inc. MUSCLE-DIRECTED COMPLEXES AND USES THEREOF IN THE TREATMENT OF DYSTROPHINOPATHIES
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US20220193250A1 (en) 2018-08-02 2022-06-23 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
IL309936A (en) 2021-07-09 2024-03-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of dystrophinopathy
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US20250339553A1 (en) 2022-04-15 2025-11-06 Dyne Therapeutics, Inc. Muscle targeting complexes and formulations for treating myotonic dystrophy
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods
WO2025259503A1 (en) * 2024-06-12 2025-12-18 Dyne Therapeutics, Inc. Biomarkers for facioscapulohumeral muscular dystrophy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012024535A2 (en) * 2010-08-18 2012-02-23 Fred Hutchinson Cancer Research Center Methods for determining the presence or risk of developing facioscapulohumeral dystrophy (fshd)
US20220193250A1 (en) * 2018-08-02 2022-06-23 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
AU2021206234A1 (en) * 2020-01-10 2022-09-01 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy

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