JPWO2023042876A5 - - Google Patents

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Publication number
JPWO2023042876A5
JPWO2023042876A5 JP2023548500A JP2023548500A JPWO2023042876A5 JP WO2023042876 A5 JPWO2023042876 A5 JP WO2023042876A5 JP 2023548500 A JP2023548500 A JP 2023548500A JP 2023548500 A JP2023548500 A JP 2023548500A JP WO2023042876 A5 JPWO2023042876 A5 JP WO2023042876A5
Authority
JP
Japan
Prior art keywords
nucleic acid
double
acid strand
stranded nucleic
acid complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023548500A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2023042876A1 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2022/034531 external-priority patent/WO2023042876A1/ja
Publication of JPWO2023042876A1 publication Critical patent/JPWO2023042876A1/ja
Publication of JPWO2023042876A5 publication Critical patent/JPWO2023042876A5/ja
Pending legal-status Critical Current

Links

JP2023548500A 2021-09-15 2022-09-15 Pending JPWO2023042876A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021150310 2021-09-15
PCT/JP2022/034531 WO2023042876A1 (ja) 2021-09-15 2022-09-15 2'-修飾ヌクレオシドを含むヘテロ核酸

Publications (2)

Publication Number Publication Date
JPWO2023042876A1 JPWO2023042876A1 (https=) 2023-03-23
JPWO2023042876A5 true JPWO2023042876A5 (https=) 2025-09-22

Family

ID=85602964

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023548500A Pending JPWO2023042876A1 (https=) 2021-09-15 2022-09-15

Country Status (4)

Country Link
US (1) US20250179486A1 (https=)
EP (1) EP4403191A4 (https=)
JP (1) JPWO2023042876A1 (https=)
WO (1) WO2023042876A1 (https=)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5276019A (en) 1987-03-25 1994-01-04 The United States Of America As Represented By The Department Of Health And Human Services Inhibitors for replication of retroviruses and for the expression of oncogene products
US5264423A (en) 1987-03-25 1993-11-23 The United States Of America As Represented By The Department Of Health And Human Services Inhibitors for replication of retroviruses and for the expression of oncogene products
US5955599A (en) 1995-06-01 1999-09-21 Hybridon, Inc. Process for making oligonucleotides containing o- and s- methylphosphotriester internucleoside linkages
JP2009536222A (ja) 2006-05-05 2009-10-08 アイシス ファーマシューティカルズ, インコーポレーテッド Pcsk9の発現を調節するための化合物および方法
CA2666191C (en) 2006-10-09 2017-07-11 Santaris Pharma A/S Rna antagonist compounds for the modulation of pcsk9
ES2526295T5 (es) 2006-10-18 2021-05-04 Ionis Pharmaceuticals Inc Compuestos antisentido
JP6112569B2 (ja) * 2011-12-16 2017-04-12 国立大学法人 東京医科歯科大学 キメラ2重鎖核酸
EP3004347B1 (en) 2013-05-30 2018-09-26 National University Corporation Tokyo Medical and Dental University Double-stranded agents for delivering therapeutic oligonucleotides
WO2015168172A1 (en) 2014-04-28 2015-11-05 Isis Pharmaceuticals, Inc. Linkage modified oligomeric compounds
WO2016081600A1 (en) 2014-11-18 2016-05-26 Zata Pharmaceuticals, Inc. Phosphoramidite synthones for the synthesis of self-neutralizing oligonucleotide compounds
EP3769769A4 (en) * 2018-03-19 2022-05-04 National University Corporation Tokyo Medical and Dental University NUCLEIC ACID WITH REDUCED TOXICITY
JP7262816B2 (ja) * 2018-03-22 2023-04-24 国立大学法人 東京医科歯科大学 ヘテロ核酸のbbb通過脂質リガンド
JP2021150310A (ja) 2020-03-16 2021-09-27 キオクシア株式会社 半導体記憶装置

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