JPWO2023042876A5 - - Google Patents
Info
- Publication number
- JPWO2023042876A5 JPWO2023042876A5 JP2023548500A JP2023548500A JPWO2023042876A5 JP WO2023042876 A5 JPWO2023042876 A5 JP WO2023042876A5 JP 2023548500 A JP2023548500 A JP 2023548500A JP 2023548500 A JP2023548500 A JP 2023548500A JP WO2023042876 A5 JPWO2023042876 A5 JP WO2023042876A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- double
- acid strand
- stranded nucleic
- acid complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021150310 | 2021-09-15 | ||
| PCT/JP2022/034531 WO2023042876A1 (ja) | 2021-09-15 | 2022-09-15 | 2'-修飾ヌクレオシドを含むヘテロ核酸 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023042876A1 JPWO2023042876A1 (https=) | 2023-03-23 |
| JPWO2023042876A5 true JPWO2023042876A5 (https=) | 2025-09-22 |
Family
ID=85602964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023548500A Pending JPWO2023042876A1 (https=) | 2021-09-15 | 2022-09-15 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20250179486A1 (https=) |
| EP (1) | EP4403191A4 (https=) |
| JP (1) | JPWO2023042876A1 (https=) |
| WO (1) | WO2023042876A1 (https=) |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5276019A (en) | 1987-03-25 | 1994-01-04 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibitors for replication of retroviruses and for the expression of oncogene products |
| US5264423A (en) | 1987-03-25 | 1993-11-23 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibitors for replication of retroviruses and for the expression of oncogene products |
| US5955599A (en) | 1995-06-01 | 1999-09-21 | Hybridon, Inc. | Process for making oligonucleotides containing o- and s- methylphosphotriester internucleoside linkages |
| JP2009536222A (ja) | 2006-05-05 | 2009-10-08 | アイシス ファーマシューティカルズ, インコーポレーテッド | Pcsk9の発現を調節するための化合物および方法 |
| CA2666191C (en) | 2006-10-09 | 2017-07-11 | Santaris Pharma A/S | Rna antagonist compounds for the modulation of pcsk9 |
| ES2526295T5 (es) | 2006-10-18 | 2021-05-04 | Ionis Pharmaceuticals Inc | Compuestos antisentido |
| JP6112569B2 (ja) * | 2011-12-16 | 2017-04-12 | 国立大学法人 東京医科歯科大学 | キメラ2重鎖核酸 |
| EP3004347B1 (en) | 2013-05-30 | 2018-09-26 | National University Corporation Tokyo Medical and Dental University | Double-stranded agents for delivering therapeutic oligonucleotides |
| WO2015168172A1 (en) | 2014-04-28 | 2015-11-05 | Isis Pharmaceuticals, Inc. | Linkage modified oligomeric compounds |
| WO2016081600A1 (en) | 2014-11-18 | 2016-05-26 | Zata Pharmaceuticals, Inc. | Phosphoramidite synthones for the synthesis of self-neutralizing oligonucleotide compounds |
| EP3769769A4 (en) * | 2018-03-19 | 2022-05-04 | National University Corporation Tokyo Medical and Dental University | NUCLEIC ACID WITH REDUCED TOXICITY |
| JP7262816B2 (ja) * | 2018-03-22 | 2023-04-24 | 国立大学法人 東京医科歯科大学 | ヘテロ核酸のbbb通過脂質リガンド |
| JP2021150310A (ja) | 2020-03-16 | 2021-09-27 | キオクシア株式会社 | 半導体記憶装置 |
-
2022
- 2022-09-15 EP EP22870023.3A patent/EP4403191A4/en active Pending
- 2022-09-15 WO PCT/JP2022/034531 patent/WO2023042876A1/ja not_active Ceased
- 2022-09-15 US US18/690,457 patent/US20250179486A1/en active Pending
- 2022-09-15 JP JP2023548500A patent/JPWO2023042876A1/ja active Pending
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