JPWO2022190967A1 - - Google Patents
Info
- Publication number
- JPWO2022190967A1 JPWO2022190967A1 JP2023505328A JP2023505328A JPWO2022190967A1 JP WO2022190967 A1 JPWO2022190967 A1 JP WO2022190967A1 JP 2023505328 A JP2023505328 A JP 2023505328A JP 2023505328 A JP2023505328 A JP 2023505328A JP WO2022190967 A1 JPWO2022190967 A1 JP WO2022190967A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Optics & Photonics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021037573 | 2021-03-09 | ||
| JP2021037573 | 2021-03-09 | ||
| PCT/JP2022/008670 WO2022190967A1 (ja) | 2021-03-09 | 2022-03-01 | リン脂質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022190967A1 true JPWO2022190967A1 (https=) | 2022-09-15 |
| JP7848179B2 JP7848179B2 (ja) | 2026-04-20 |
Family
ID=83227160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023505328A Active JP7848179B2 (ja) | 2021-03-09 | 2022-03-01 | リン脂質 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230295199A1 (https=) |
| EP (1) | EP4306531A4 (https=) |
| JP (1) | JP7848179B2 (https=) |
| CN (1) | CN116234538A (https=) |
| WO (1) | WO2022190967A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120712274A (zh) * | 2023-02-14 | 2025-09-26 | 静冈县公立大学法人 | pH响应性磷脂 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4826936A (https=) * | 1971-08-14 | 1973-04-09 | ||
| JPS5484530A (en) * | 1977-11-24 | 1979-07-05 | Max Planck Gesellschaft | Novel compounds of phosphorus lipid analogues* their manufacture and manufacture of plant mongrels |
| JPS6041494A (ja) * | 1983-04-11 | 1985-03-05 | Meito Sangyo Kk | 酵素法リン脂質一級アルコ−ル誘導体の製法 |
| JP2005247750A (ja) * | 2004-03-04 | 2005-09-15 | Takemoto Oil & Fat Co Ltd | リン脂質誘導体及び遺伝子導入キャリア |
| WO2018190017A1 (ja) * | 2017-04-11 | 2018-10-18 | 日本精化株式会社 | 核酸導入用脂質誘導体 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10207177A1 (de) * | 2002-02-19 | 2003-09-04 | Novosom Ag | Fakultativ kationische Lipide |
| WO2019005830A1 (en) * | 2017-06-26 | 2019-01-03 | Fordoz Pharma Corp. | NANOSOME FORMULATIONS OF APREPITANT AND METHODS AND APPLICATIONS THEREOF |
-
2022
- 2022-03-01 US US18/017,751 patent/US20230295199A1/en active Pending
- 2022-03-01 WO PCT/JP2022/008670 patent/WO2022190967A1/ja not_active Ceased
- 2022-03-01 EP EP22766926.4A patent/EP4306531A4/en active Pending
- 2022-03-01 CN CN202280006255.1A patent/CN116234538A/zh active Pending
- 2022-03-01 JP JP2023505328A patent/JP7848179B2/ja active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4826936A (https=) * | 1971-08-14 | 1973-04-09 | ||
| JPS5484530A (en) * | 1977-11-24 | 1979-07-05 | Max Planck Gesellschaft | Novel compounds of phosphorus lipid analogues* their manufacture and manufacture of plant mongrels |
| JPS6041494A (ja) * | 1983-04-11 | 1985-03-05 | Meito Sangyo Kk | 酵素法リン脂質一級アルコ−ル誘導体の製法 |
| JP2005247750A (ja) * | 2004-03-04 | 2005-09-15 | Takemoto Oil & Fat Co Ltd | リン脂質誘導体及び遺伝子導入キャリア |
| WO2018190017A1 (ja) * | 2017-04-11 | 2018-10-18 | 日本精化株式会社 | 核酸導入用脂質誘導体 |
Non-Patent Citations (3)
| Title |
|---|
| ASAI, T. ET AL.: "Dicetyl phosphate-tetraethylenepentamine-based liposomes for systemic siRNA delivery", BIOCONJUGATE CHEMISTRY, vol. 22, no. 3, JPN6018018575, 2011, pages 429 - 435, ISSN: 0005812883 * |
| NAGATA, T. ET AL.: "Fusion of plant protoplasts induced by a positively charged synthetic phospholipid", ZEITSCHRIFT FUER NATURFORSCHUNG, C: JOURNAL OF BIOSCIENCES, vol. Vol. 34C, No. 5-6, JPN6018018573, 1979, pages 460 - 462, ISSN: 0005812884 * |
| 冨田 康治 他: "ピペラジン骨格を有する新規機能性脂質の開発", 第３６回日本ＤＤＳ学会学術集会プログラム予稿集, JPN6022019765, 10 August 2020 (2020-08-10), pages 197, ISSN: 0005738063 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20230295199A1 (en) | 2023-09-21 |
| EP4306531A1 (en) | 2024-01-17 |
| WO2022190967A1 (ja) | 2022-09-15 |
| JP7848179B2 (ja) | 2026-04-20 |
| CN116234538A (zh) | 2023-06-06 |
| EP4306531A4 (en) | 2025-02-19 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20250228 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20251125 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20260108 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20260310 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20260408 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 7848179 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |