JPWO2022125891A5 - - Google Patents
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- Publication number
- JPWO2022125891A5 JPWO2022125891A5 JP2023535317A JP2023535317A JPWO2022125891A5 JP WO2022125891 A5 JPWO2022125891 A5 JP WO2022125891A5 JP 2023535317 A JP2023535317 A JP 2023535317A JP 2023535317 A JP2023535317 A JP 2023535317A JP WO2022125891 A5 JPWO2022125891 A5 JP WO2022125891A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- alkyldiyl
- cdr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063124353P | 2020-12-11 | 2020-12-11 | |
| US63/124,353 | 2020-12-11 | ||
| PCT/US2021/062797 WO2022125891A2 (en) | 2020-12-11 | 2021-12-10 | Anti-cea immunoconjugates, and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024501453A JP2024501453A (ja) | 2024-01-12 |
| JP2024501453A5 JP2024501453A5 (https=) | 2024-12-10 |
| JPWO2022125891A5 true JPWO2022125891A5 (https=) | 2024-12-10 |
Family
ID=79425667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023535317A Withdrawn JP2024501453A (ja) | 2020-12-11 | 2021-12-10 | 抗ｃｅａイムノコンジュゲート、及びそれらの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240238430A1 (https=) |
| EP (1) | EP4259210A2 (https=) |
| JP (1) | JP2024501453A (https=) |
| CN (1) | CN116635084A (https=) |
| CA (1) | CA3200051A1 (https=) |
| WO (1) | WO2022125891A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023154318A1 (en) * | 2022-02-09 | 2023-08-17 | Bolt Biotherapeutics, Inc. | Anti-tr0p2, aminobenzazepine immunoconjugates, and uses thereof |
| WO2024173387A1 (en) | 2023-02-14 | 2024-08-22 | Bolt Biotherapeutics, Inc. | Aza-benzazepine immunoconjugates, and uses thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988007089A1 (en) | 1987-03-18 | 1988-09-22 | Medical Research Council | Altered antibodies |
| US5874540A (en) | 1994-10-05 | 1999-02-23 | Immunomedics, Inc. | CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies |
| CA2399940A1 (en) | 2000-04-13 | 2001-10-25 | The Rockefeller University | Enhancement of antibody-mediated immune responses |
| US7232888B2 (en) | 2002-07-01 | 2007-06-19 | Massachusetts Institute Of Technology | Antibodies against tumor surface antigens |
| WO2005086875A2 (en) | 2004-03-11 | 2005-09-22 | City Of Hope | A humanized anti-cea t84.66 antibody and uses thereof |
| KR101270829B1 (ko) | 2004-09-23 | 2013-06-07 | 제넨테크, 인크. | 시스테인 유전자조작 항체 및 접합체 |
| WO2006073921A2 (en) | 2004-12-30 | 2006-07-13 | The Rockefeller University | Compositions and methods for enhanced dendritic cell maturation and function |
| US20080286819A1 (en) | 2005-11-07 | 2008-11-20 | Ravetch Jeffrey V | Reagents, Methods and Systems for Selecting a Cytotoxic Antibody or Variant Thereof |
| LT1976880T (lt) | 2005-12-21 | 2016-10-10 | Amgen Research (Munich) Gmbh | Farmacinės kompozicijos, pasižyminčios atsparumu tirpiam cea |
| EP2144628B1 (en) | 2007-05-08 | 2012-10-17 | Genentech, Inc. | Cysteine engineered anti-muc16 antibodies and antibody drug conjugates |
| MX2010003718A (es) | 2007-10-19 | 2010-04-21 | Genentech Inc | Anticuerpos anti-tenb2 producidos por ingenieria de cisteina y conjugados de farmaco y anticuerpo. |
| JP5889912B2 (ja) | 2010-11-17 | 2016-03-22 | ジェネンテック， インコーポレイテッド | アラニニルメイタンシノール抗体コンジュゲート |
| RS56793B1 (sr) | 2011-03-02 | 2018-04-30 | Roche Glycart Ag | Cea antitela |
| HUE033369T2 (en) | 2012-11-20 | 2017-11-28 | Sanofi Sa | Anti-ceacam5 antibodies and uses thereof |
| US9676863B2 (en) | 2014-02-10 | 2017-06-13 | Merck Patent Gmbh | Targeted TGFβ inhibitors |
| MY189836A (en) | 2014-11-21 | 2022-03-11 | Bristol Myers Squibb Co | Antibodies against cd73 and uses thereof |
| AU2019337654A1 (en) * | 2018-09-12 | 2021-04-08 | Silverback Therapeutics, Inc. | Substituted benzazepine compounds, conjugates, and uses thereof |
| WO2020252254A1 (en) * | 2019-06-13 | 2020-12-17 | Bolt Biotherapeutics, Inc. | Macromolecule-supported aminobenzazepine compounds |
| AU2020291014B2 (en) * | 2019-06-13 | 2025-06-05 | Bolt Biotherapeutics, Inc. | Aminobenzazepine compounds, immunoconjugates, and uses thereof |
| CN115996756A (zh) * | 2020-05-08 | 2023-04-21 | 博尔特生物治疗药物有限公司 | 弹性蛋白酶底物肽连接子免疫缀合物及其用途 |
-
2021
- 2021-12-10 CN CN202180083382.7A patent/CN116635084A/zh active Pending
- 2021-12-10 US US18/038,904 patent/US20240238430A1/en active Pending
- 2021-12-10 EP EP21841071.0A patent/EP4259210A2/en not_active Withdrawn
- 2021-12-10 JP JP2023535317A patent/JP2024501453A/ja not_active Withdrawn
- 2021-12-10 CA CA3200051A patent/CA3200051A1/en active Pending
- 2021-12-10 WO PCT/US2021/062797 patent/WO2022125891A2/en not_active Ceased
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