JPWO2022080455A1 - - Google Patents
Info
- Publication number
- JPWO2022080455A1 JPWO2022080455A1 JP2022557440A JP2022557440A JPWO2022080455A1 JP WO2022080455 A1 JPWO2022080455 A1 JP WO2022080455A1 JP 2022557440 A JP2022557440 A JP 2022557440A JP 2022557440 A JP2022557440 A JP 2022557440A JP WO2022080455 A1 JPWO2022080455 A1 JP WO2022080455A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/33—Insulin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1315—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from cardiomyocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Cardiology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025067532A JP2025106562A (ja) | 2020-10-14 | 2025-04-16 | 心筋幹／前駆細胞の作製方法及び心筋線維化抑制方法 |
| JP2025067533A JP2025106563A (ja) | 2020-10-14 | 2025-04-16 | 心筋幹／前駆細胞の作製方法及び心筋線維化抑制方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020173581 | 2020-10-14 | ||
| JP2020173581 | 2020-10-14 | ||
| PCT/JP2021/038071 WO2022080455A1 (ja) | 2020-10-14 | 2021-10-14 | 心筋幹／前駆細胞の作製方法及び心筋線維化抑制方法 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025067532A Division JP2025106562A (ja) | 2020-10-14 | 2025-04-16 | 心筋幹／前駆細胞の作製方法及び心筋線維化抑制方法 |
| JP2025067533A Division JP2025106563A (ja) | 2020-10-14 | 2025-04-16 | 心筋幹／前駆細胞の作製方法及び心筋線維化抑制方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022080455A1 true JPWO2022080455A1 (https=) | 2022-04-21 |
| JP7672720B2 JP7672720B2 (ja) | 2025-05-08 |
Family
ID=81208122
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022557440A Active JP7672720B2 (ja) | 2020-10-14 | 2021-10-14 | 心筋幹／前駆細胞の作製方法及び心筋線維化抑制方法 |
| JP2025067533A Pending JP2025106563A (ja) | 2020-10-14 | 2025-04-16 | 心筋幹／前駆細胞の作製方法及び心筋線維化抑制方法 |
| JP2025067532A Pending JP2025106562A (ja) | 2020-10-14 | 2025-04-16 | 心筋幹／前駆細胞の作製方法及び心筋線維化抑制方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025067533A Pending JP2025106563A (ja) | 2020-10-14 | 2025-04-16 | 心筋幹／前駆細胞の作製方法及び心筋線維化抑制方法 |
| JP2025067532A Pending JP2025106562A (ja) | 2020-10-14 | 2025-04-16 | 心筋幹／前駆細胞の作製方法及び心筋線維化抑制方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230374462A1 (https=) |
| EP (1) | EP4215602A4 (https=) |
| JP (3) | JP7672720B2 (https=) |
| CN (1) | CN116806257A (https=) |
| CA (1) | CA3195608A1 (https=) |
| TW (1) | TW202227615A (https=) |
| WO (1) | WO2022080455A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3062949T3 (en) * | 2018-10-15 | 2026-04-14 | Evia Life Sciences Inc | Method for producing stem/precursor cells, by using low molecular weight compound, from cells derived from endodermal tissue or organ |
| CN116536255B (zh) * | 2023-07-05 | 2023-09-12 | 夏同生物科技(苏州)有限公司 | 一种高效诱导肌肉干细胞的培养基及方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018225705A1 (ja) * | 2017-06-05 | 2018-12-13 | テルモ株式会社 | 細胞培養物の製造方法 |
| WO2020067439A1 (ja) * | 2018-09-27 | 2020-04-02 | 国立大学法人大阪大学 | 心筋細胞のシート化方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180273906A1 (en) * | 2014-04-17 | 2018-09-27 | Muhammad Ashraf | Microvesicle and stem cell compositions for therapeutic applications |
| JP2018079714A (ja) | 2016-11-14 | 2018-05-24 | 株式会社ケーヒン | 車両用空調装置 |
-
2021
- 2021-10-14 TW TW110138177A patent/TW202227615A/zh unknown
- 2021-10-14 EP EP21880190.0A patent/EP4215602A4/en active Pending
- 2021-10-14 CA CA3195608A patent/CA3195608A1/en active Pending
- 2021-10-14 JP JP2022557440A patent/JP7672720B2/ja active Active
- 2021-10-14 CN CN202180070427.7A patent/CN116806257A/zh active Pending
- 2021-10-14 WO PCT/JP2021/038071 patent/WO2022080455A1/ja not_active Ceased
-
2023
- 2023-04-13 US US18/134,298 patent/US20230374462A1/en active Pending
-
2025
- 2025-04-16 JP JP2025067533A patent/JP2025106563A/ja active Pending
- 2025-04-16 JP JP2025067532A patent/JP2025106562A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018225705A1 (ja) * | 2017-06-05 | 2018-12-13 | テルモ株式会社 | 細胞培養物の製造方法 |
| WO2020067439A1 (ja) * | 2018-09-27 | 2020-04-02 | 国立大学法人大阪大学 | 心筋細胞のシート化方法 |
Non-Patent Citations (3)
| Title |
|---|
| CHU L. ET AL., NAUNYN SCHMIEDEBERGS ARCH PHARMACOL, vol. 371, JPN6024038424, 2005, pages 185 - 194, ISSN: 0005442856 * |
| SATOH, S. ET AL., BIOCHEM. BIOPHYS. RES. COMMUN., vol. 424, JPN6021044807, 2012, pages 338 - 340, ISSN: 0005442855 * |
| 松浦 勝久: "細胞シートを用いた心筋前駆細胞移植による梗塞後心筋修復の分子機序の解明", 科学研究費補助金研究成果報告書, JPN6024038425, 2011, ISSN: 0005442854 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20230374462A1 (en) | 2023-11-23 |
| JP2025106563A (ja) | 2025-07-15 |
| EP4215602A4 (en) | 2024-11-06 |
| JP7672720B2 (ja) | 2025-05-08 |
| JP2025106562A (ja) | 2025-07-15 |
| CA3195608A1 (en) | 2022-04-21 |
| EP4215602A1 (en) | 2023-07-26 |
| WO2022080455A1 (ja) | 2022-04-21 |
| TW202227615A (zh) | 2022-07-16 |
| CN116806257A (zh) | 2023-09-26 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20230403 |
|
| AA64 | Notification of invalidation of claim of internal priority (with term) |
Free format text: JAPANESE INTERMEDIATE CODE: A241764 Effective date: 20230627 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230704 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230721 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20240402 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20240603 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20241022 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20241223 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20250318 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20250416 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 7672720 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |