JPWO2022071417A1 - - Google Patents

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Publication number
JPWO2022071417A1
JPWO2022071417A1 JP2022554051A JP2022554051A JPWO2022071417A1 JP WO2022071417 A1 JPWO2022071417 A1 JP WO2022071417A1 JP 2022554051 A JP2022554051 A JP 2022554051A JP 2022554051 A JP2022554051 A JP 2022554051A JP WO2022071417 A1 JPWO2022071417 A1 JP WO2022071417A1
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022554051A
Other languages
Japanese (ja)
Other versions
JPWO2022071417A5 (https=
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed filed Critical
Publication of JPWO2022071417A1 publication Critical patent/JPWO2022071417A1/ja
Publication of JPWO2022071417A5 publication Critical patent/JPWO2022071417A5/ja
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/005Enzyme electrodes involving specific analytes or enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/02Oxidoreductases acting on the CH-OH group of donors (1.1) with a cytochrome as acceptor (1.1.2)
    • C12Y101/02003L-Lactate dehydrogenase (cytochrome) (1.1.2.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01027L-Lactate dehydrogenase (1.1.1.27)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01028D-Lactate dehydrogenase (1.1.1.28)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/902Oxidoreductases (1.)
    • G01N2333/904Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2022554051A 2020-09-29 2021-09-29 Pending JPWO2022071417A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020163631 2020-09-29
PCT/JP2021/035929 WO2022071417A1 (ja) 2020-09-29 2021-09-29 フラビン依存性乳酸デヒドロゲナーゼを含む組成物の安定性を向上する方法

Publications (2)

Publication Number Publication Date
JPWO2022071417A1 true JPWO2022071417A1 (https=) 2022-04-07
JPWO2022071417A5 JPWO2022071417A5 (https=) 2024-10-04

Family

ID=80950645

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022554051A Pending JPWO2022071417A1 (https=) 2020-09-29 2021-09-29

Country Status (5)

Country Link
US (1) US20230365959A1 (https=)
EP (1) EP4223884A4 (https=)
JP (1) JPWO2022071417A1 (https=)
KR (1) KR20230078697A (https=)
WO (1) WO2022071417A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7714520B2 (ja) * 2020-02-21 2025-07-29 キッコーマン株式会社 検体の状態を評価するためのデバイス、それを含むシステム、検体の状態を評価する方法及びそれに用いる乳酸デヒドロゲナーゼ
CN120404876A (zh) * 2025-03-21 2025-08-01 亳州学院 检测西布曲明含量的电化学免疫传感器、西布曲明检测试剂盒

Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58175498A (ja) * 1982-03-26 1983-10-14 メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 液体中の物質の測定用試験系および試験方法
JPS61159164A (ja) * 1984-09-21 1986-07-18 ジヨナサン・エル・キ−ル ミクロ化学発光アツセイシステム
JPH01104172A (ja) * 1987-10-16 1989-04-21 Agency Of Ind Science & Technol 酵素の安定化法
JPH034791A (ja) * 1989-05-30 1991-01-10 Kanebo Ltd 酵素の安定化方法
JPH04271785A (ja) * 1991-02-28 1992-09-28 Kao Corp 酵素固形製剤及びその製造方法
JPH1169973A (ja) * 1997-08-29 1999-03-16 Kao Corp 酵素の安定化方法
JP2000513940A (ja) * 1996-07-03 2000-10-24 モレキュラー バイオロジー リソーシス,インコーポレイテッド 酵素の安定化のための方法および処方物
JP2007129965A (ja) * 2005-11-11 2007-05-31 Toyobo Co Ltd 可溶性補酵素結合型のグルコースデヒドロゲナーゼ(gdh)を含む組成物の熱安定性を向上する方法
JP2007163268A (ja) * 2005-12-13 2007-06-28 Canon Inc 酵素電極
JP2008154573A (ja) * 2006-03-31 2008-07-10 Toyobo Co Ltd 可溶性グルコースデヒドロゲナーゼ(gdh)を含む組成物の安定性を向上する方法
JP2009034095A (ja) * 2007-07-06 2009-02-19 Sanyo Chem Ind Ltd タンパク質含有水溶液安定化剤、タンパク質含有水溶液の安定化方法及びタンパク質含有水溶液
JP2012099242A (ja) * 2010-10-29 2012-05-24 Toyota Motor Corp 酵素燃料電池
JP2014018096A (ja) * 2012-07-13 2014-02-03 Kikkoman Corp フラビン結合型グルコースデヒドロゲナーゼを含む組成物の安定性を向上する方法
JP2015008707A (ja) * 2013-07-02 2015-01-19 東洋紡株式会社 酵素の安定化方法
JP2015177790A (ja) * 2014-02-27 2015-10-08 キッコーマン株式会社 アマドリアーゼ含有組成物の安定化方法、熱安定性が向上したアマドリアーゼ含有組成物及びこれを用いた糖化ヘモグロビン測定用組成物
WO2019201894A1 (en) * 2018-04-16 2019-10-24 Merck Patent Gmbh Additives for protein formulations to improve thermal stability

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3191016B1 (en) 2014-09-09 2021-10-27 University of Washington Functionalized zwitterionic and mixed charge polymers, related hydrogels, and methods for their use
JP6484742B1 (ja) 2018-04-13 2019-03-13 キッコーマン株式会社 新規メディエータ
JP6484741B1 (ja) 2018-04-13 2019-03-13 キッコーマン株式会社 新規メディエータ
JP7814828B2 (ja) 2019-03-28 2026-02-17 大日本印刷株式会社 樹脂フィルム、積層体及び包装製品
JP7714520B2 (ja) * 2020-02-21 2025-07-29 キッコーマン株式会社 検体の状態を評価するためのデバイス、それを含むシステム、検体の状態を評価する方法及びそれに用いる乳酸デヒドロゲナーゼ

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58175498A (ja) * 1982-03-26 1983-10-14 メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 液体中の物質の測定用試験系および試験方法
JPS61159164A (ja) * 1984-09-21 1986-07-18 ジヨナサン・エル・キ−ル ミクロ化学発光アツセイシステム
JPH01104172A (ja) * 1987-10-16 1989-04-21 Agency Of Ind Science & Technol 酵素の安定化法
JPH034791A (ja) * 1989-05-30 1991-01-10 Kanebo Ltd 酵素の安定化方法
JPH04271785A (ja) * 1991-02-28 1992-09-28 Kao Corp 酵素固形製剤及びその製造方法
JP2000513940A (ja) * 1996-07-03 2000-10-24 モレキュラー バイオロジー リソーシス,インコーポレイテッド 酵素の安定化のための方法および処方物
JPH1169973A (ja) * 1997-08-29 1999-03-16 Kao Corp 酵素の安定化方法
JP2007129965A (ja) * 2005-11-11 2007-05-31 Toyobo Co Ltd 可溶性補酵素結合型のグルコースデヒドロゲナーゼ(gdh)を含む組成物の熱安定性を向上する方法
JP2007163268A (ja) * 2005-12-13 2007-06-28 Canon Inc 酵素電極
JP2008154573A (ja) * 2006-03-31 2008-07-10 Toyobo Co Ltd 可溶性グルコースデヒドロゲナーゼ(gdh)を含む組成物の安定性を向上する方法
JP2009034095A (ja) * 2007-07-06 2009-02-19 Sanyo Chem Ind Ltd タンパク質含有水溶液安定化剤、タンパク質含有水溶液の安定化方法及びタンパク質含有水溶液
JP2012099242A (ja) * 2010-10-29 2012-05-24 Toyota Motor Corp 酵素燃料電池
JP2014018096A (ja) * 2012-07-13 2014-02-03 Kikkoman Corp フラビン結合型グルコースデヒドロゲナーゼを含む組成物の安定性を向上する方法
JP2015008707A (ja) * 2013-07-02 2015-01-19 東洋紡株式会社 酵素の安定化方法
JP2015177790A (ja) * 2014-02-27 2015-10-08 キッコーマン株式会社 アマドリアーゼ含有組成物の安定化方法、熱安定性が向上したアマドリアーゼ含有組成物及びこれを用いた糖化ヘモグロビン測定用組成物
WO2019201894A1 (en) * 2018-04-16 2019-10-24 Merck Patent Gmbh Additives for protein formulations to improve thermal stability

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"A0A4T0X365, July 31, 2019 uploaded, [retrieved Apr 16, 2021], Definition: Uncharacterized protein", DATABASE UNIPROT[ONLINE], JPN6021015338, ISSN: 0005687867 *
PROTEIN SCIENCE, vol. 8, JPN6025037618, 1999, pages 222 - 233, ISSN: 0005687868 *

Also Published As

Publication number Publication date
EP4223884A1 (en) 2023-08-09
WO2022071417A1 (ja) 2022-04-07
EP4223884A4 (en) 2024-12-11
KR20230078697A (ko) 2023-06-02
US20230365959A1 (en) 2023-11-16

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