JPWO2022057875A5 - - Google Patents

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Publication number
JPWO2022057875A5
JPWO2022057875A5 JP2023517935A JP2023517935A JPWO2022057875A5 JP WO2022057875 A5 JPWO2022057875 A5 JP WO2022057875A5 JP 2023517935 A JP2023517935 A JP 2023517935A JP 2023517935 A JP2023517935 A JP 2023517935A JP WO2022057875 A5 JPWO2022057875 A5 JP WO2022057875A5
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JP
Japan
Prior art keywords
single domain
domain antibody
cancer
fusion protein
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023517935A
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English (en)
Japanese (ja)
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JP2023542900A (ja
JP2023542900A5 (https=
Publication date
Priority claimed from CN202011025265.9A external-priority patent/CN114195894B/zh
Application filed filed Critical
Publication of JP2023542900A publication Critical patent/JP2023542900A/ja
Publication of JP2023542900A5 publication Critical patent/JP2023542900A5/ja
Publication of JPWO2022057875A5 publication Critical patent/JPWO2022057875A5/ja
Pending legal-status Critical Current

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JP2023517935A 2020-09-17 2021-09-17 4-1bbを標的とする単一ドメイン抗体、その融合タンパク質、その医薬組成物及び使用 Pending JP2023542900A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN202010981835.5 2020-09-17
CN202010981835 2020-09-17
CN202011025265.9A CN114195894B (zh) 2020-09-17 2020-09-25 一种靶向4-1bb的抗体及其应用
CN202011025265.9 2020-09-25
PCT/CN2021/118955 WO2022057875A1 (zh) 2020-09-17 2021-09-17 靶向4-1bb的单域抗体、其融合蛋白、药物组合物及用途

Publications (3)

Publication Number Publication Date
JP2023542900A JP2023542900A (ja) 2023-10-12
JP2023542900A5 JP2023542900A5 (https=) 2024-09-18
JPWO2022057875A5 true JPWO2022057875A5 (https=) 2024-09-18

Family

ID=80645420

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023517935A Pending JP2023542900A (ja) 2020-09-17 2021-09-17 4-1bbを標的とする単一ドメイン抗体、その融合タンパク質、その医薬組成物及び使用

Country Status (8)

Country Link
US (1) US20230357422A1 (https=)
EP (1) EP4215547A4 (https=)
JP (1) JP2023542900A (https=)
KR (1) KR20230070238A (https=)
CN (2) CN114195894B (https=)
AU (1) AU2021342525A1 (https=)
CA (1) CA3195676A1 (https=)
WO (1) WO2022057875A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250075621A (ko) * 2022-09-20 2025-05-28 바이오세우스 인크. 항체 및 종양 저항에서의 이의 용도
KR20250157389A (ko) * 2023-03-01 2025-11-04 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 Fap/4-1bb/cd40 결합 분자 및 이의 의학적 용도
WO2025002405A1 (zh) * 2023-06-30 2025-01-02 百奥泰生物制药股份有限公司 4-1bb结合蛋白
CN117736330B (zh) * 2024-01-24 2024-05-17 上海沙砾生物科技有限公司 肿瘤坏死因子超家族受体9的特异性抗原结合蛋白及其应用
WO2025214249A1 (en) * 2024-04-12 2025-10-16 Suzhou Biomissile Pharmaceuticals Co., Ltd. Anti-4-bb single domain antibodies, bispecific antibodies and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US7288638B2 (en) * 2003-10-10 2007-10-30 Bristol-Myers Squibb Company Fully human antibodies against human 4-1BB
PT2614082T (pt) * 2010-09-09 2018-12-03 Pfizer Moléculas de ligação a 4-1bb
KR20180096789A (ko) * 2016-01-11 2018-08-29 인히브릭스, 인크. 다가 및 다중특이적 41bb-결합 융합 단백질
US10174122B2 (en) * 2017-01-06 2019-01-08 Eutilex Co., Ltd. Anti-human 4-1BB antibodies and uses thereof
WO2019092452A1 (en) * 2017-11-13 2019-05-16 Crescendo Biologics Limited Molecules that bind to cd137 and psma
WO2019109238A1 (en) * 2017-12-05 2019-06-13 Lyvgen Biopharma Co., Ltd. Anti-cd137 antibodies and uses thereof
CN109970865B (zh) * 2017-12-28 2022-10-04 上海细胞治疗研究院 一种cd137双向激活共刺激分子受体及其用途
CA3089260A1 (en) * 2018-01-22 2019-07-25 Jiangsu Hengrui Medicine Co., Ltd. Anti-4-1bb antibody, antigen-binding fragment thereof and medical use thereof
WO2020023553A1 (en) * 2018-07-24 2020-01-30 Inhibrx, Inc. Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same
CN110627906B (zh) * 2019-10-10 2020-07-28 上海洛启生物医药技术有限公司 抗pd-l1/4-1bb双特异性抗体及其用途

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