JP2023542900A5 - - Google Patents

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Publication number
JP2023542900A5
JP2023542900A5 JP2023517935A JP2023517935A JP2023542900A5 JP 2023542900 A5 JP2023542900 A5 JP 2023542900A5 JP 2023517935 A JP2023517935 A JP 2023517935A JP 2023517935 A JP2023517935 A JP 2023517935A JP 2023542900 A5 JP2023542900 A5 JP 2023542900A5
Authority
JP
Japan
Prior art keywords
domain antibody
cancer
fusion protein
antibody according
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023517935A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023542900A (ja
Filing date
Publication date
Priority claimed from CN202011025265.9A external-priority patent/CN114195894B/zh
Application filed filed Critical
Publication of JP2023542900A publication Critical patent/JP2023542900A/ja
Publication of JP2023542900A5 publication Critical patent/JP2023542900A5/ja
Pending legal-status Critical Current

Links

JP2023517935A 2020-09-17 2021-09-17 4-1bbを標的とする単一ドメイン抗体、その融合タンパク質、その医薬組成物及び使用 Pending JP2023542900A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN202010981835 2020-09-17
CN202010981835.5 2020-09-17
CN202011025265.9A CN114195894B (zh) 2020-09-17 2020-09-25 一种靶向4-1bb的抗体及其应用
CN202011025265.9 2020-09-25
PCT/CN2021/118955 WO2022057875A1 (zh) 2020-09-17 2021-09-17 靶向4-1bb的单域抗体、其融合蛋白、药物组合物及用途

Publications (2)

Publication Number Publication Date
JP2023542900A JP2023542900A (ja) 2023-10-12
JP2023542900A5 true JP2023542900A5 (https=) 2024-09-18

Family

ID=80645420

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023517935A Pending JP2023542900A (ja) 2020-09-17 2021-09-17 4-1bbを標的とする単一ドメイン抗体、その融合タンパク質、その医薬組成物及び使用

Country Status (8)

Country Link
US (1) US20230357422A1 (https=)
EP (1) EP4215547A4 (https=)
JP (1) JP2023542900A (https=)
KR (1) KR20230070238A (https=)
CN (2) CN114195894B (https=)
AU (1) AU2021342525A1 (https=)
CA (1) CA3195676A1 (https=)
WO (1) WO2022057875A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119894933A (zh) * 2022-09-20 2025-04-25 普米斯生物技术(珠海)有限公司 抗体及其在抗肿瘤中的应用
TW202436358A (zh) * 2023-03-01 2024-09-16 大陸商江蘇恆瑞醫藥股份有限公司 Fap/4-1bb/cd40結合分子及其醫藥用途
WO2025002405A1 (zh) * 2023-06-30 2025-01-02 百奥泰生物制药股份有限公司 4-1bb结合蛋白
CN117736330B (zh) * 2024-01-24 2024-05-17 上海沙砾生物科技有限公司 肿瘤坏死因子超家族受体9的特异性抗原结合蛋白及其应用
WO2025214249A1 (en) * 2024-04-12 2025-10-16 Suzhou Biomissile Pharmaceuticals Co., Ltd. Anti-4-bb single domain antibodies, bispecific antibodies and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US7288638B2 (en) 2003-10-10 2007-10-30 Bristol-Myers Squibb Company Fully human antibodies against human 4-1BB
MX337040B (es) * 2010-09-09 2016-02-09 Pfizer Moleculas de union a 4-1bb.
KR20180096789A (ko) * 2016-01-11 2018-08-29 인히브릭스, 인크. 다가 및 다중특이적 41bb-결합 융합 단백질
CN112210010B (zh) * 2017-01-06 2023-12-05 优特力克斯有限公司 抗-人4-1bb抗体及其应用
EP3710478A1 (en) * 2017-11-13 2020-09-23 Crescendo Biologics Limited Molecules that bind to cd137 and psma
WO2019109238A1 (en) * 2017-12-05 2019-06-13 Lyvgen Biopharma Co., Ltd. Anti-cd137 antibodies and uses thereof
CN109970865B (zh) * 2017-12-28 2022-10-04 上海细胞治疗研究院 一种cd137双向激活共刺激分子受体及其用途
KR20200113228A (ko) * 2018-01-22 2020-10-06 지앙수 헨그루이 메디슨 컴퍼니 리미티드 항-4-1bb 항체, 이의 항원-결합 단편 및 이의 의학적 용도
EP3827019A1 (en) * 2018-07-24 2021-06-02 Inhibrx, Inc. Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same
CN112646031B (zh) * 2019-10-10 2021-12-07 天境生物科技(上海)有限公司 抗4-1bb纳米抗体及其用途

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