JPWO2022051537A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2022051537A5 JPWO2022051537A5 JP2023514415A JP2023514415A JPWO2022051537A5 JP WO2022051537 A5 JPWO2022051537 A5 JP WO2022051537A5 JP 2023514415 A JP2023514415 A JP 2023514415A JP 2023514415 A JP2023514415 A JP 2023514415A JP WO2022051537 A5 JPWO2022051537 A5 JP WO2022051537A5
- Authority
- JP
- Japan
- Prior art keywords
- raav
- pharmaceutical composition
- capsid protein
- mir
- vegf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063074361P | 2020-09-03 | 2020-09-03 | |
| US63/074,361 | 2020-09-03 | ||
| US202163179700P | 2021-04-26 | 2021-04-26 | |
| US63/179,700 | 2021-04-26 | ||
| PCT/US2021/048917 WO2022051537A1 (en) | 2020-09-03 | 2021-09-02 | Adeno-associated virus for delivery of kh902 (conbercept) and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023540094A JP2023540094A (ja) | 2023-09-21 |
| JPWO2022051537A5 true JPWO2022051537A5 (https=) | 2024-09-06 |
| JP2023540094A5 JP2023540094A5 (https=) | 2024-09-06 |
Family
ID=80491540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023514415A Pending JP2023540094A (ja) | 2020-09-03 | 2021-09-02 | Kh902(コンベルセプト)の送達のためのアデノ随伴ウイルスおよびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230340529A1 (https=) |
| EP (1) | EP4208478A4 (https=) |
| JP (1) | JP2023540094A (https=) |
| KR (1) | KR20230061441A (https=) |
| AU (1) | AU2021336425A1 (https=) |
| BR (1) | BR112023003548A2 (https=) |
| CA (1) | CA3192736A1 (https=) |
| IL (1) | IL300864A (https=) |
| MX (1) | MX2023002695A (https=) |
| WO (1) | WO2022051537A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020006435A (es) | 2017-12-19 | 2021-02-09 | Akouos Inc | Administracion de anticuerpos terapeuticos mediada por vector de virus adenoasociado (aav) en el oido interno. |
| IL303317A (en) | 2020-12-01 | 2023-07-01 | Akouos Inc | ANTI-NATURAL ANTIBODY STRUCTURES AND RELATED METHODS FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH VESTIBULAR SWANNOMA |
| AU2024247959A1 (en) * | 2023-03-28 | 2025-10-09 | General Medicines Llc | Nucleic acid off-switches and methods and uses thereof |
| WO2024220389A2 (en) * | 2023-04-17 | 2024-10-24 | University Of Massachusetts | Aav2 variants and uses thereof |
| CN119656336A (zh) * | 2023-09-21 | 2025-03-21 | 成都弘基生物科技有限公司 | 一种重组腺相关病毒在制备治疗与血管新生相关眼病的药物中的用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100897379B1 (ko) * | 2004-06-08 | 2009-05-14 | 쳉두 캉홍 바이오테크놀로지스 코. 리미티드 | 혈관신생-저해 키메릭 단백질 및 그 사용 |
| AU2014286996A1 (en) * | 2013-07-12 | 2016-01-07 | Iveric Bio, Inc. | Methods for treating or preventing ophthalmological conditions |
| EP3134522B1 (en) * | 2014-04-25 | 2021-10-06 | University of Massachusetts | Recombinant aav vectors useful for reducing immunity against transgene products |
| US11046955B2 (en) * | 2015-04-24 | 2021-06-29 | University Of Massachusetts | Modified AAV constructs and uses thereof |
| DK3471780T3 (da) * | 2016-06-16 | 2020-11-23 | Adverum Biotechnologies Inc | Behandling af amd med aav2-variant med aflibercept |
| AU2018227483A1 (en) * | 2017-02-28 | 2019-09-12 | Adverum Biotechnologies, Inc. | Modified AAV capsids and uses thereof |
| AU2018350990A1 (en) * | 2017-10-18 | 2020-05-21 | Regenxbio Inc. | Treatment of ocular diseases and metastatic colon cancer with human post-translationally modified VEGF-Trap |
| KR102205830B1 (ko) * | 2017-10-26 | 2021-01-21 | 주식회사 큐로진생명과학 | 솔루블 VEGFR-1 변이체 cDNA를 함유하는 rAAV를 포함하는 황반변성 치료용 조성물 |
| US11103552B2 (en) * | 2018-05-10 | 2021-08-31 | Regeneron Pharmaceuticals, Inc. | High concentration VEGF receptor fusion protein containing formulations |
-
2021
- 2021-09-02 BR BR112023003548A patent/BR112023003548A2/pt unknown
- 2021-09-02 MX MX2023002695A patent/MX2023002695A/es unknown
- 2021-09-02 CA CA3192736A patent/CA3192736A1/en active Pending
- 2021-09-02 WO PCT/US2021/048917 patent/WO2022051537A1/en not_active Ceased
- 2021-09-02 JP JP2023514415A patent/JP2023540094A/ja active Pending
- 2021-09-02 KR KR1020237010791A patent/KR20230061441A/ko active Pending
- 2021-09-02 AU AU2021336425A patent/AU2021336425A1/en active Pending
- 2021-09-02 EP EP21865133.9A patent/EP4208478A4/en active Pending
- 2021-09-02 IL IL300864A patent/IL300864A/en unknown
- 2021-09-02 US US18/024,359 patent/US20230340529A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Bordet et al. | Ocular gene therapies in clinical practice: viral vectors and nonviral alternatives | |
| US11851657B2 (en) | Anti-angiogenic miRNA therapeutics for inhibiting corneal neovascularization | |
| JP7182873B2 (ja) | 多重ベクターシステム及びその使用 | |
| JP2019000114A (ja) | 希突起神経膠細胞を標的とするアデノ随伴ウイルスベクター | |
| CA3130515A1 (en) | Crispr/rna-guided nuclease-related methods and compositions for treating rho-associated autosomal-dominant retinitis pigmentosa (adrp) | |
| JP2017500060A (ja) | 対象の網膜色素上皮において目的のポリヌクレオチドを発現させるための方法および医薬組成物 | |
| JP7289306B2 (ja) | 網膜障害を治療するための組成物及び方法 | |
| US20220332792A1 (en) | Adeno-associated virus vector platform for delivery of kh902 (conbercept) and uses thereof | |
| US20260001917A1 (en) | Modified adeno-associated virus capsid proteins and methods thereof | |
| US20230057380A1 (en) | Recombinant adeno-associated virus for delivery of kh902 (conbercept) and uses thereof | |
| CA3117551A1 (en) | Compositions and methods for treating age-related macular degeneration and other diseases | |
| US20230340529A1 (en) | Adeno-associated virus for delivery of kh902 (conbercept) and uses thereof | |
| CN114144518A (zh) | 用于基因疗法的双亮氨酸拉链激酶抑制剂 | |
| JPWO2022076711A5 (https=) | ||
| EP4045152A1 (en) | Methods for modulating level of expression from gene therapy expression cassette | |
| JPWO2020219933A5 (https=) | ||
| JPWO2022051537A5 (https=) | ||
| CN112424368A (zh) | 用于调节眼内压和颅内压的材料和方法 | |
| US12570997B2 (en) | Factor H vectors and uses thereof | |
| CN117736274A (zh) | 一种腺相关病毒衣壳蛋白及其用途 | |
| CN115997012B (zh) | Rpe65相关眼睛疾病和障碍的治疗 | |
| RU2846105C1 (ru) | Аденоассоциированный вирус для доставки kh902 (конберцепта) и его применения | |
| US20230048017A1 (en) | Adeno-associated virus for delivery of kh902 (conbercept) and uses thereof | |
| CN118146317A (zh) | 一种腺相关病毒衣壳蛋白及其用途 | |
| WO2022169863A1 (en) | Method of gene delivery to retinal astrocytes |