JPWO2021241616A5 - - Google Patents

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Publication number
JPWO2021241616A5
JPWO2021241616A5 JP2022526603A JP2022526603A JPWO2021241616A5 JP WO2021241616 A5 JPWO2021241616 A5 JP WO2021241616A5 JP 2022526603 A JP2022526603 A JP 2022526603A JP 2022526603 A JP2022526603 A JP 2022526603A JP WO2021241616 A5 JPWO2021241616 A5 JP WO2021241616A5
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JP
Japan
Prior art keywords
amino acid
seq
acid sequence
human
antibody
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022526603A
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English (en)
Japanese (ja)
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JPWO2021241616A1 (https=
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Priority claimed from PCT/JP2021/019929 external-priority patent/WO2021241616A1/ja
Publication of JPWO2021241616A1 publication Critical patent/JPWO2021241616A1/ja
Publication of JPWO2021241616A5 publication Critical patent/JPWO2021241616A5/ja
Pending legal-status Critical Current

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JP2022526603A 2020-05-27 2021-05-26 Pending JPWO2021241616A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020092105 2020-05-27
PCT/JP2021/019929 WO2021241616A1 (ja) 2020-05-27 2021-05-26 抗ヒトnr1抗体誘導体

Publications (2)

Publication Number Publication Date
JPWO2021241616A1 JPWO2021241616A1 (https=) 2021-12-02
JPWO2021241616A5 true JPWO2021241616A5 (https=) 2024-06-05

Family

ID=78744563

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022526603A Pending JPWO2021241616A1 (https=) 2020-05-27 2021-05-26

Country Status (11)

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US (2) US20230220070A1 (https=)
EP (1) EP4159859A4 (https=)
JP (1) JPWO2021241616A1 (https=)
KR (1) KR20230029671A (https=)
CN (2) CN120737200A (https=)
AU (1) AU2021281828A1 (https=)
BR (1) BR112022023931A2 (https=)
CA (1) CA3180470A1 (https=)
IL (1) IL298537A (https=)
MX (1) MX2022014856A (https=)
WO (1) WO2021241616A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021241616A1 (ja) 2020-05-27 2021-12-02 アステラス製薬株式会社 抗ヒトnr1抗体誘導体
JP7730432B2 (ja) 2022-10-19 2025-08-27 アステラス製薬株式会社 がん治療におけるpd-1シグナル阻害剤との組み合わせによる抗cldn4-抗cd137二重特異性抗体の使用
AU2024242885A1 (en) * 2023-03-30 2025-09-11 Arialys Therapeutics, Inc. Detection of autoantibodies against nr1
WO2026033259A1 (en) * 2024-08-05 2026-02-12 Lys Therapeutics Antibodies for treating neurological and neurovascular disorders
WO2026044177A1 (en) * 2024-08-23 2026-02-26 Janssen Biotech, Inc. Methods of treatment with gprc5d antibodies with enhanced effector function

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
ATE299938T1 (de) 1997-05-02 2005-08-15 Genentech Inc Ein verfahren zur herstellung multispezifischer antikörper die heteromultimere und gemeinsame komponenten besitzen
PT1718677E (pt) * 2003-12-19 2012-07-18 Genentech Inc Fragmentos de anticorpo monovalentes úteis como agentes terapêuticos
EP2805972A1 (en) 2013-05-21 2014-11-26 PAION Deutschland GmbH Novel antibody useful in neurological or neurodegenerative disorders
RU2018109230A (ru) * 2015-08-17 2019-09-19 ДОЙЧЕС ЦЕНТРУМ ФЮР НОЙРОДЕГЕНЕРАТИВЕ ЭРКРАНКУНГЕН е.Ф. (ДЦНЭ) Антитело, или фрагмент антитела, или неиммуноглобулиновый каркас, связывающийся с областью связывания антитела против рецептора n-метил-d-аспартата (nmda)
WO2019246071A1 (en) 2018-06-18 2019-12-26 Denali Therapeutics Inc. Fusion proteins comprising progranulin
WO2020204977A1 (en) 2019-03-29 2020-10-08 Lankenau Institute For Medical Research Anti-nmda receptor antibodies and methods of use
EP3999850A1 (en) 2019-07-16 2022-05-25 Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) Nmda receptor constructs to detect and isolate nmdar autoantibodies
WO2021241616A1 (ja) 2020-05-27 2021-12-02 アステラス製薬株式会社 抗ヒトnr1抗体誘導体
CN114891091B (zh) 2022-06-13 2024-04-26 四川携光生物技术有限公司 一种抗nmdar脑炎重组抗原及应用
AU2024242885A1 (en) 2023-03-30 2025-09-11 Arialys Therapeutics, Inc. Detection of autoantibodies against nr1

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