JPWO2021237223A5 - - Google Patents

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Publication number
JPWO2021237223A5
JPWO2021237223A5 JP2022571745A JP2022571745A JPWO2021237223A5 JP WO2021237223 A5 JPWO2021237223 A5 JP WO2021237223A5 JP 2022571745 A JP2022571745 A JP 2022571745A JP 2022571745 A JP2022571745 A JP 2022571745A JP WO2021237223 A5 JPWO2021237223 A5 JP WO2021237223A5
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JP
Japan
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invention described
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Pending
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JP2022571745A
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English (en)
Japanese (ja)
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JP2023526975A (ja
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Priority claimed from PCT/US2021/033945 external-priority patent/WO2021237223A1/en
Publication of JP2023526975A publication Critical patent/JP2023526975A/ja
Publication of JPWO2021237223A5 publication Critical patent/JPWO2021237223A5/ja
Pending legal-status Critical Current

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JP2022571745A 2020-05-22 2021-05-24 オリゴヌクレオチド組成物及びその方法 Pending JP2023526975A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063029387P 2020-05-22 2020-05-22
US63/029,387 2020-05-22
PCT/US2021/033945 WO2021237223A1 (en) 2020-05-22 2021-05-24 Oligonucleotide compositions and methods thereof

Publications (2)

Publication Number Publication Date
JP2023526975A JP2023526975A (ja) 2023-06-26
JPWO2021237223A5 true JPWO2021237223A5 (cg-RX-API-DMAC7.html) 2024-05-31

Family

ID=78707682

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022571745A Pending JP2023526975A (ja) 2020-05-22 2021-05-24 オリゴヌクレオチド組成物及びその方法

Country Status (6)

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US (1) US20230203087A1 (cg-RX-API-DMAC7.html)
EP (1) EP4153604A4 (cg-RX-API-DMAC7.html)
JP (1) JP2023526975A (cg-RX-API-DMAC7.html)
AU (1) AU2021277407A1 (cg-RX-API-DMAC7.html)
CA (1) CA3176986A1 (cg-RX-API-DMAC7.html)
WO (1) WO2021237223A1 (cg-RX-API-DMAC7.html)

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ES2940887T3 (es) 2012-07-13 2023-05-12 Wave Life Sciences Ltd Método de preparación de oligonucleótidos quirales
CN113278617A (zh) 2014-01-16 2021-08-20 波涛生命科学有限公司 手性设计
MA43072A (fr) 2015-07-22 2018-05-30 Wave Life Sciences Ltd Compositions d'oligonucléotides et procédés associés
WO2017210647A1 (en) 2016-06-03 2017-12-07 Wave Life Sciences Ltd. Oligonucleotides, compositions and methods thereof
WO2017220751A1 (en) 2016-06-22 2017-12-28 Proqr Therapeutics Ii B.V. Single-stranded rna-editing oligonucleotides
DK3507366T3 (da) 2016-09-01 2020-11-02 Proqr Therapeutics Ii Bv Kemisk modificeret, enkeltstrengede rna-modificerende oligonukleotider
JP7296882B2 (ja) 2016-11-23 2023-06-23 ウェイブ ライフ サイエンシズ リミテッド ホスホラミダイト及びオリゴヌクレオチド合成のための組成物及び方法
JP7557941B2 (ja) 2017-06-02 2024-09-30 ウェイブ ライフ サイエンシズ リミテッド オリゴヌクレオチド組成物及びその使用方法
JP2020522510A (ja) 2017-06-02 2020-07-30 ウェイブ ライフ サイエンシズ リミテッドWave Life Sciences Ltd. オリゴヌクレオチド組成物及びその使用方法
JP7402696B2 (ja) 2017-06-21 2023-12-21 ウェイブ ライフ サイエンシズ リミテッド 合成のための化合物、組成物、及び方法
CN111032057A (zh) 2017-08-08 2020-04-17 波涛生命科学有限公司 寡核苷酸组合物及其方法
KR20250123934A (ko) 2017-09-18 2025-08-18 웨이브 라이프 사이언시스 리미티드 올리고뉴클레오티드 제조 기술
EP3694530A4 (en) 2017-10-12 2021-06-30 Wave Life Sciences Ltd. COMPOSITIONS OF OLIGONUCLEOTIDES AND RELATED PROCESSES
US12391942B2 (en) 2018-05-11 2025-08-19 Wave Life Sciences Ltd. Oligonucleotide compositions and methods of use thereof
GB201808146D0 (en) 2018-05-18 2018-07-11 Proqr Therapeutics Ii Bv Stereospecific Linkages in RNA Editing Oligonucleotides
WO2023152371A1 (en) 2022-02-14 2023-08-17 Proqr Therapeutics Ii B.V. Guide oligonucleotides for nucleic acid editing in the treatment of hypercholesterolemia
EP4555085A1 (en) 2022-07-15 2025-05-21 ProQR Therapeutics II B.V. Chemically modified oligonucleotides for adar-mediated rna editing
JP2025524566A (ja) 2022-07-15 2025-07-30 プロキューアール セラピューティクス ツー ベスローテン フェンノートシャップ Adar媒介rna編集のためのオリゴヌクレオチドおよびその使用
GB202215614D0 (en) 2022-10-21 2022-12-07 Proqr Therapeutics Ii Bv Heteroduplex rna editing oligonucleotide complexes
TW202435897A (zh) 2022-11-24 2024-09-16 荷蘭商Proqr治療上市公司Ii 用於治療遺傳性hfe血色沉著病之反義寡核苷酸
GB202218090D0 (en) 2022-12-01 2023-01-18 Proqr Therapeutics Ii Bv Antisense oligonucleotides for the treatment of aldehyde dehydrogenase 2 deficiency
AU2023390632A1 (en) 2022-12-09 2025-07-10 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of cardiovascular disease
GB202300865D0 (en) 2023-01-20 2023-03-08 Proqr Therapeutics Ii Bv Delivery of oligonucleotides
EP4669753A1 (en) 2023-02-20 2025-12-31 ProQR Therapeutics II B.V. Antisense oligonucleotides for the treatment of atherosclerotic cardiovascular disease
WO2024206175A1 (en) 2023-03-24 2024-10-03 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of neurological disorders
GB202304363D0 (en) 2023-03-24 2023-05-10 Proqr Therapeutics Ii Bv Chemically modified antisense oligonucleotides for use in RNA editing
WO2024200472A1 (en) 2023-03-27 2024-10-03 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of liver disease
TW202516003A (zh) 2023-06-16 2025-04-16 荷蘭商Proqr治療上市公司Ii 用於治療神經退化性疾病之反義寡核苷酸
WO2025051946A1 (en) 2023-09-07 2025-03-13 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of metabolic disorders
WO2025070241A1 (ja) * 2023-09-25 2025-04-03 藤本化学製品株式会社 化合物又はその塩、並びにその製造方法
WO2025072886A1 (en) * 2023-09-28 2025-04-03 Wave Life Sciences Ltd. Oligonucleotide compositions and methods thereof
AU2024369609A1 (en) * 2023-10-31 2025-12-11 Korro Bio, Inc. Oligonucleotides comprising phosphoramidate internucleotide linkages
WO2025104239A1 (en) 2023-11-16 2025-05-22 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of classic galactosemia
WO2025132708A1 (en) 2023-12-20 2025-06-26 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of huntington's disease
WO2025151895A1 (en) * 2024-01-12 2025-07-17 Wave Life Sciences Ltd. Oligonucleotide compositions and methods thereof
GB202404661D0 (en) 2024-04-02 2024-05-15 Proqr Therapeutics Ii Bv Antisense oligoncleotides for the treatment of liver disease
WO2025224230A1 (en) 2024-04-25 2025-10-30 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of fatty liver disease

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US5216168A (en) * 1992-04-01 1993-06-01 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars
WO2011005860A2 (en) * 2009-07-07 2011-01-13 Alnylam Pharmaceuticals, Inc. 5' phosphate mimics
RU2708237C2 (ru) * 2014-08-22 2019-12-05 Общество с ограниченной ответственностью "НооГен" Модифицированные олигонуклеотиды и способ их получения
SG10202101836TA (en) * 2016-05-24 2021-03-30 Sarepta Therapeutics Inc Processes for preparing phosphorodiamidate morpholino oligomers
US20220306573A1 (en) * 2018-04-12 2022-09-29 Jason Jingxi ZHANG Oligonucleotide compositions and methods of use thereof
US12391942B2 (en) * 2018-05-11 2025-08-19 Wave Life Sciences Ltd. Oligonucleotide compositions and methods of use thereof

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