JPWO2021191447A5 - - Google Patents
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- Publication number
- JPWO2021191447A5 JPWO2021191447A5 JP2022558063A JP2022558063A JPWO2021191447A5 JP WO2021191447 A5 JPWO2021191447 A5 JP WO2021191447A5 JP 2022558063 A JP2022558063 A JP 2022558063A JP 2022558063 A JP2022558063 A JP 2022558063A JP WO2021191447 A5 JPWO2021191447 A5 JP WO2021191447A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- protein
- seq
- intein
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20382236.6A EP3885440A1 (en) | 2020-03-26 | 2020-03-26 | Split inteins and their uses |
| EP20382236.6 | 2020-03-26 | ||
| PCT/EP2021/058016 WO2021191447A1 (en) | 2020-03-26 | 2021-03-26 | Split inteins and their uses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023518596A JP2023518596A (ja) | 2023-05-02 |
| JPWO2021191447A5 true JPWO2021191447A5 (https=) | 2024-04-05 |
| JP2023518596A5 JP2023518596A5 (https=) | 2024-04-05 |
Family
ID=70292931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022558063A Pending JP2023518596A (ja) | 2020-03-26 | 2021-03-26 | スプリットインテイン及びその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230116688A1 (https=) |
| EP (2) | EP3885440A1 (https=) |
| JP (1) | JP2023518596A (https=) |
| KR (1) | KR20220160052A (https=) |
| CN (1) | CN115698307A (https=) |
| AU (1) | AU2021241899A1 (https=) |
| BR (1) | BR112022019167A2 (https=) |
| CA (1) | CA3175696A1 (https=) |
| IL (1) | IL296712A (https=) |
| WO (1) | WO2021191447A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210055733A (ko) | 2018-09-07 | 2021-05-17 | 빔 테라퓨틱스, 인크. | 핵염기 편집 시스템을 전달하기 위한 조성물 및 방법 |
| CA3152679A1 (en) * | 2019-08-28 | 2021-03-04 | The Trustees Of Princeton University | Atypical split inteins and uses thereof |
| JP7807380B2 (ja) | 2020-02-21 | 2026-01-27 | アコーオス インコーポレイテッド | ヒト対象において非加齢関連聴力障害を処置するための組成物および方法 |
| US20250319126A1 (en) * | 2021-10-29 | 2025-10-16 | Shanghai Sinobay Biotechnology Co., Ltd. | Condition-controlled spliceable chimeric antigen receptor molecule and application thereof |
| EP4527933A4 (en) * | 2022-05-17 | 2025-12-24 | Eye & Ent Hospital Of Fudan Univ | DUAL-SUPPORT SYSTEM FOR THE TREATMENT OF HEARING LOSS, AND ITS USE |
| AU2024214841A1 (en) * | 2023-02-01 | 2025-08-28 | Allen Institute | Intein-mediated reconstitution of voltage-gated sodium channel function |
| EP4726045A1 (en) | 2023-06-07 | 2026-04-15 | Peking University Third Hospital (The Third Clinical Medical School of Peking University) | Expression cassette combination and use thereof |
| WO2025038955A1 (en) * | 2023-08-16 | 2025-02-20 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Systems and methods for improving safety of split intein aav mediated gene therapy |
| AU2024338787A1 (en) | 2023-09-04 | 2026-03-19 | Splicebio, Sl | Use of split intein for the treatment of scn1a associated disease |
| WO2025153705A1 (en) | 2024-01-18 | 2025-07-24 | Splicebio, Sl | Use of split intein for the treatment of myo7a-associated disease |
| WO2025193938A1 (en) * | 2024-03-13 | 2025-09-18 | Oregon Health & Science University | Delivery of type iv collagen alpha chain using a split intein dual aav vector |
| WO2026013288A1 (en) | 2024-07-12 | 2026-01-15 | Splicebio, Sl | Split intein for use in the treatment of cep290-associated disease |
| WO2026057767A1 (en) * | 2024-09-13 | 2026-03-19 | Splicebio, Sl | Use of split intein for the treatment of abca3-associated disease |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5100792A (en) | 1984-11-13 | 1992-03-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues |
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5036006A (en) | 1984-11-13 | 1991-07-30 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| FR2714830B1 (fr) | 1994-01-10 | 1996-03-22 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2715847B1 (fr) | 1994-02-08 | 1996-04-12 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2727679B1 (fr) | 1994-12-05 | 1997-01-03 | Rhone Poulenc Rorer Sa | Nouveaux agents de transfection et leurs applications pharmaceutiques |
| FR2730637B1 (fr) | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
| US8298818B2 (en) | 2006-04-28 | 2012-10-30 | University Of Florida Research Foundation, Inc. | Self-complementary adeno-associated virus having a truncated CMV-chicken β-actin promoter |
| RS63416B1 (sr) * | 2015-03-03 | 2022-08-31 | Fond Telethon | Sistem višestrukih vektora i njegove primene |
| EP3312279B1 (en) * | 2015-06-19 | 2020-10-14 | Riken | pH-RESPONSIVE PROTEOLYSIS PROBE |
| ES2949163T3 (es) * | 2016-01-29 | 2023-09-26 | Univ Princeton | Inteínas divididas con actividad de corte y empalme excepcional |
| AU2019360372B2 (en) * | 2018-10-15 | 2026-02-26 | Fondazione Telethon | Intein proteins and uses thereof |
-
2020
- 2020-03-26 EP EP20382236.6A patent/EP3885440A1/en active Pending
-
2021
- 2021-03-26 KR KR1020227037261A patent/KR20220160052A/ko active Pending
- 2021-03-26 IL IL296712A patent/IL296712A/en unknown
- 2021-03-26 EP EP21713447.7A patent/EP4127194A1/en active Pending
- 2021-03-26 AU AU2021241899A patent/AU2021241899A1/en active Pending
- 2021-03-26 CA CA3175696A patent/CA3175696A1/en active Pending
- 2021-03-26 WO PCT/EP2021/058016 patent/WO2021191447A1/en not_active Ceased
- 2021-03-26 US US17/914,212 patent/US20230116688A1/en active Pending
- 2021-03-26 BR BR112022019167A patent/BR112022019167A2/pt unknown
- 2021-03-26 JP JP2022558063A patent/JP2023518596A/ja active Pending
- 2021-03-26 CN CN202180038835.4A patent/CN115698307A/zh active Pending
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