JPWO2021187593A5 - - Google Patents
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- Publication number
- JPWO2021187593A5 JPWO2021187593A5 JP2022508439A JP2022508439A JPWO2021187593A5 JP WO2021187593 A5 JPWO2021187593 A5 JP WO2021187593A5 JP 2022508439 A JP2022508439 A JP 2022508439A JP 2022508439 A JP2022508439 A JP 2022508439A JP WO2021187593 A5 JPWO2021187593 A5 JP WO2021187593A5
- Authority
- JP
- Japan
- Prior art keywords
- polyoxyethylene
- composition
- ether
- group
- stability
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 polyoxyethylene Polymers 0.000 claims description 24
- 239000000203 mixture Substances 0.000 claims description 19
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 15
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 12
- 229960004311 betamethasone valerate Drugs 0.000 claims description 9
- SNHRLVCMMWUAJD-SUYDQAKGSA-N betamethasone valerate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(OC(=O)CCCC)[C@@]1(C)C[C@@H]2O SNHRLVCMMWUAJD-SUYDQAKGSA-N 0.000 claims description 9
- 150000005215 alkyl ethers Chemical class 0.000 claims description 6
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 5
- 229960001295 tocopherol Drugs 0.000 claims description 5
- 229930003799 tocopherol Natural products 0.000 claims description 5
- 235000010384 tocopherol Nutrition 0.000 claims description 5
- 239000011732 tocopherol Substances 0.000 claims description 5
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 5
- 230000007423 decrease Effects 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 2
- 230000001629 suppression Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 8
- 238000004519 manufacturing process Methods 0.000 claims 5
- 150000002170 ethers Chemical class 0.000 claims 3
- 239000003002 pH adjusting agent Substances 0.000 claims 3
- 239000004909 Moisturizer Substances 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 claims 1
- 230000001139 anti-pruritic effect Effects 0.000 claims 1
- 239000003908 antipruritic agent Substances 0.000 claims 1
- 239000003899 bactericide agent Substances 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 230000017531 blood circulation Effects 0.000 claims 1
- 239000002826 coolant Substances 0.000 claims 1
- 239000003589 local anesthetic agent Substances 0.000 claims 1
- 230000001333 moisturizer Effects 0.000 claims 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 1
- 238000009472 formulation Methods 0.000 description 4
- 230000002349 favourable effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020049760 | 2020-03-19 | ||
| JP2020049760 | 2020-03-19 | ||
| PCT/JP2021/011180 WO2021187593A1 (ja) | 2020-03-19 | 2021-03-18 | ベタメタゾン吉草酸エステル含有組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2021187593A1 JPWO2021187593A1 (https=) | 2021-09-23 |
| JPWO2021187593A5 true JPWO2021187593A5 (https=) | 2023-06-28 |
| JP7350985B2 JP7350985B2 (ja) | 2023-09-26 |
Family
ID=77770984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022508439A Active JP7350985B2 (ja) | 2020-03-19 | 2021-03-18 | ベタメタゾン吉草酸エステル含有組成物 |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP7350985B2 (https=) |
| TW (1) | TWI885097B (https=) |
| WO (1) | WO2021187593A1 (https=) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09110696A (ja) * | 1995-10-18 | 1997-04-28 | Sekisui Chem Co Ltd | 皮膚疾患治療用外用剤 |
| PT3146969T (pt) * | 1999-04-23 | 2018-10-18 | Leo Pharma As | Composição farmacêutica para aplicação dérmica para uso no tratamento da psoríase compreendendo vitamina d e um corticosteroide |
| JP4690672B2 (ja) * | 2004-07-20 | 2011-06-01 | 岩城製薬株式会社 | 乳剤性皮膚外用剤 |
| EP2097065A2 (en) * | 2006-11-29 | 2009-09-09 | Foamix Ltd. | Foamable waterless compositions with modulating agents |
-
2021
- 2021-03-18 WO PCT/JP2021/011180 patent/WO2021187593A1/ja not_active Ceased
- 2021-03-18 JP JP2022508439A patent/JP7350985B2/ja active Active
- 2021-03-19 TW TW110110082A patent/TWI885097B/zh active
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