JPWO2021113365A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2021113365A5
JPWO2021113365A5 JP2022534275A JP2022534275A JPWO2021113365A5 JP WO2021113365 A5 JPWO2021113365 A5 JP WO2021113365A5 JP 2022534275 A JP2022534275 A JP 2022534275A JP 2022534275 A JP2022534275 A JP 2022534275A JP WO2021113365 A5 JPWO2021113365 A5 JP WO2021113365A5
Authority
JP
Japan
Prior art keywords
alkyl
optionally substituted
hydrogen
compound
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022534275A
Other languages
English (en)
Japanese (ja)
Other versions
JP7699128B2 (ja
JP2023505316A5 (https=
JP2023505316A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/062893 external-priority patent/WO2021113365A1/en
Publication of JP2023505316A publication Critical patent/JP2023505316A/ja
Publication of JPWO2021113365A5 publication Critical patent/JPWO2021113365A5/ja
Publication of JP2023505316A5 publication Critical patent/JP2023505316A5/ja
Application granted granted Critical
Publication of JP7699128B2 publication Critical patent/JP7699128B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022534275A 2019-12-06 2020-12-02 ナノマテリアル Active JP7699128B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962944735P 2019-12-06 2019-12-06
US62/944,735 2019-12-06
PCT/US2020/062893 WO2021113365A1 (en) 2019-12-06 2020-12-02 Nanomaterials

Publications (4)

Publication Number Publication Date
JP2023505316A JP2023505316A (ja) 2023-02-08
JPWO2021113365A5 true JPWO2021113365A5 (https=) 2023-11-30
JP2023505316A5 JP2023505316A5 (https=) 2023-11-30
JP7699128B2 JP7699128B2 (ja) 2025-06-26

Family

ID=76209418

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022534275A Active JP7699128B2 (ja) 2019-12-06 2020-12-02 ナノマテリアル

Country Status (7)

Country Link
US (2) US20210169804A1 (https=)
EP (1) EP4069675A4 (https=)
JP (1) JP7699128B2 (https=)
KR (1) KR20220113737A (https=)
AU (1) AU2020396940A1 (https=)
CA (1) CA3160395A1 (https=)
WO (1) WO2021113365A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12569438B2 (en) 2019-07-29 2026-03-10 Georgia Tech Research Corporation Nanomaterials containing constrained lipids and uses thereof
US12435035B2 (en) 2020-01-09 2025-10-07 Guide Therapeutics, Llc Nanomaterials
CZ310613B6 (cs) 2020-09-23 2026-01-28 Ústav organické chemie a biochemie AV ČR, v. v. i. Lipidoidy pro transfekci nukleových kyselin a jejich použití
JP2023546175A (ja) 2020-10-14 2023-11-01 ジョージ・メイソン・リサーチ・ファウンデーション・インコーポレイテッド 脂質ナノ粒子製造の方法及びそれに由来する組成物
WO2022140239A1 (en) * 2020-12-21 2022-06-30 Beam Therapeutics Inc. Nanomaterials comprising carbonates
IL303845A (en) 2021-01-20 2023-08-01 Beam Therapeutics Inc Nanomaterials include a degradable property
KR20230131863A (ko) 2021-01-20 2023-09-14 빔 테라퓨틱스, 인크. 나노물질
CZ310443B6 (cs) 2021-07-19 2025-06-25 Ústav organické chemie a biochemie AV ČR, v. v. i. Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití
US20250346554A1 (en) * 2021-12-16 2025-11-13 Jsr Corporation Method for purifying composition
CN114436994B (zh) * 2022-01-26 2024-02-27 中国药科大学 金刚烷尾链脂质及其在细胞转染中的应用
EP4532713A1 (en) 2022-05-27 2025-04-09 Beam Therapeutics Inc. Identification of nanoparticles for preferential tissue or cell targeting
EP4543847A2 (en) * 2022-06-23 2025-04-30 Turn Biotechnologies, Inc. Lipid structures and compositions comprising same
WO2024019936A1 (en) 2022-07-20 2024-01-25 Beam Therapeutics Inc. Nanomaterials comprising triols
JP2025539561A (ja) * 2022-12-12 2025-12-05 コリア・インスティテュート・オブ・サイエンス・アンド・テクノロジー 新規な脂質化合物及びそれを含む脂質ナノ粒子組成物
US12311033B2 (en) 2023-05-31 2025-05-27 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
CN119490447A (zh) * 2023-08-17 2025-02-21 苏州星核迪赛生物技术有限公司 药物递送材料及其应用
WO2025076049A1 (en) * 2023-10-03 2025-04-10 Broadpharm Inc. Lipid compounds, lipid nanoparticles, and pharmaceutical compositions
WO2026035680A1 (en) 2024-08-06 2026-02-12 Kernal Biologics, Inc. Compositions and methods for delivery of agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL257307A (https=) * 1959-10-28
US3686238A (en) * 1970-01-19 1972-08-22 Syntex Corp Glycerol esterified with 2-naphthyl-acetic acids and fatty acids
DE102007029471A1 (de) 2007-06-20 2008-12-24 Novosom Ag Neue fakultativ kationische Sterole
ES2895651T3 (es) * 2013-12-19 2022-02-22 Novartis Ag Lípidos y composiciones lipídicas para la administración de agentes activos
EP3727362A4 (en) * 2017-12-19 2021-10-06 PureTech LYT, Inc. MYCOPHENOLIC ACID LIPID PRODRUGS AND THEIR USES
US20210300962A1 (en) * 2018-08-02 2021-09-30 Puretech Lyt, Inc. Lipid prodrugs of pregnane neurosteroids and uses thereof
US12594339B2 (en) * 2019-02-28 2026-04-07 Seaport Therapeutics, Inc. Lipid prodrugs of JAK inhibitors and uses thereof
WO2020176868A1 (en) * 2019-02-28 2020-09-03 Puretech Lyt, Inc. Lipid prodrugs of btk inhibitors and uses thereof
WO2020176856A1 (en) * 2019-02-28 2020-09-03 Puretech Lyt, Inc. Lipid prodrugs of glucocorticoids and uses thereof
US12569438B2 (en) * 2019-07-29 2026-03-10 Georgia Tech Research Corporation Nanomaterials containing constrained lipids and uses thereof

Similar Documents

Publication Publication Date Title
JPWO2021113365A5 (https=)
AU2023200568C1 (en) Novel lipids and compositions for the delivery of therapeutics
JPWO2021141969A5 (https=)
JP5902197B2 (ja) Peg化脂質および薬剤送達のためのそれらの使用
JP2025181861A5 (https=)
AU2022268351A1 (en) Di-aliphatic substituted pegylated lipids
CA2767129C (en) Compositions and methods for silencing apolipoprotein b
JP7748500B2 (ja) トリループを含む二本鎖核酸インヒビター分子
JP2020176135A (ja) 陽イオン性脂質およびその使用方法
JP2012509273A5 (https=)
AU2017379901B2 (en) Methods for ameliorating infusion reactions
IL257382A (en) Nucleic acid-lipid particles, compositions comprising the same and uses thereof
RU2018113459A (ru) Фармацевтическая композиция, содержащая анионное лекарственное средство, и способ ее получения
BR112014020824B1 (pt) Lipídeo, partícula de lipídeo e composição farmacêutica
EP3634431A1 (en) Therapeutic compositions and methods for treating hepatitis b
WO2018232330A1 (en) Therapeutic compositions and methods for treating hepatitis b
JPWO2023078950A5 (https=)
RU2011101733A (ru) Носитель лекарственного средства
WO2011135141A4 (es) Oligonucleótidos modificados como reguladores de la expresión génica
HK40092425A (en) Novel lipids and compositions for the delivery of therapeutics
EA048677B1 (ru) Липиды и композиции для доставки лекарственных средств
HK1161096B (en) Novel lipids and compositions for the delivery of therapeutics
HK1161096A (en) Novel lipids and compositions for the delivery of therapeutics