JPWO2021107154A1 - - Google Patents

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Publication number
JPWO2021107154A1
JPWO2021107154A1 JP2021561585A JP2021561585A JPWO2021107154A1 JP WO2021107154 A1 JPWO2021107154 A1 JP WO2021107154A1 JP 2021561585 A JP2021561585 A JP 2021561585A JP 2021561585 A JP2021561585 A JP 2021561585A JP WO2021107154 A1 JPWO2021107154 A1 JP WO2021107154A1
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JP
Japan
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JP2021561585A
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JP7448831B2 (ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2021561585A 2019-11-29 2020-11-27 アルツハイマー型認知症又は軽度認知障害の診断を補助する方法、バイオマーカー、試薬キット及び装置 Active JP7448831B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019217482 2019-11-29
JP2019217482 2019-11-29
PCT/JP2020/044399 WO2021107154A1 (ja) 2019-11-29 2020-11-27 アルツハイマー型認知症又は軽度認知障害の診断を補助する方法、バイオマーカー、試薬キット及び装置

Publications (2)

Publication Number Publication Date
JPWO2021107154A1 true JPWO2021107154A1 (ja) 2021-06-03
JP7448831B2 JP7448831B2 (ja) 2024-03-13

Family

ID=76129638

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021561585A Active JP7448831B2 (ja) 2019-11-29 2020-11-27 アルツハイマー型認知症又は軽度認知障害の診断を補助する方法、バイオマーカー、試薬キット及び装置

Country Status (5)

Country Link
US (1) US20220291242A1 (ja)
EP (1) EP4067906A4 (ja)
JP (1) JP7448831B2 (ja)
CN (1) CN115176163A (ja)
WO (1) WO2021107154A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115190974A (zh) * 2019-11-29 2022-10-14 富士胶片和光纯药株式会社 辅助帕金森氏病的诊断的方法、生物标志物、试剂盒及装置
WO2022250009A1 (ja) * 2021-05-26 2022-12-01 富士フイルム株式会社 レビー小体病とアルツハイマー病の鑑別を補助する方法、バイオマーカー、及び試薬キット
WO2023058627A1 (ja) * 2021-10-04 2023-04-13 国立大学法人北海道大学 認知症の検査方法
WO2023232108A1 (zh) * 2022-06-02 2023-12-07 浙江大学医学院附属第一医院 诊断及鉴别诊断非阿尔兹海默病认知障碍的方法、系统、组合物和试剂盒
WO2024122459A1 (ja) * 2022-12-05 2024-06-13 アルメッド株式会社 認知機能障害ステージを判定する方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013054534A1 (ja) * 2011-10-14 2013-04-18 国立大学法人北海道大学 アミロイドβ関連の疾患用医薬及びそのスクリーニング
WO2016088689A1 (ja) * 2014-12-05 2016-06-09 和光純薬工業株式会社 Ｔｉｍタンパク質結合担体、当該担体を用いた細胞外膜小胞及びウイルスの取得方法、除去方法、検出方法並びに当該担体を含むキット
JP2016161480A (ja) * 2015-03-04 2016-09-05 国立大学法人 千葉大学 微量の微小胞の定量、診断及びスクリーニング方法
JP2016535283A (ja) * 2013-10-24 2016-11-10 ナノソミックス・インコーポレイテッドＮａｎｏＳｏｍｉＸ， Ｉｎｃ． アルツハイマー病および他の神経変性障害のためのバイオマーカーおよび診断方法
WO2019058303A1 (en) * 2017-09-21 2019-03-28 Braindtech S.P.A. DIAGNOSTIC AND PROGNOSTIC METHODS FOR NEURODEGENERATIVE AND NEUROINFLAMMATORY DISEASES
JP2021012189A (ja) * 2019-07-04 2021-02-04 国立研究開発法人産業技術総合研究所 がん及び神経変性疾患の検出方法
WO2022250009A1 (ja) * 2021-05-26 2022-12-01 富士フイルム株式会社 レビー小体病とアルツハイマー病の鑑別を補助する方法、バイオマーカー、及び試薬キット

Family Cites Families (4)

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US7897356B2 (en) * 2008-11-12 2011-03-01 Caris Life Sciences Methods and systems of using exosomes for determining phenotypes
US9590760B2 (en) 2014-06-03 2017-03-07 Raytheon Company Analog RF memory system
US11243215B2 (en) * 2016-01-14 2022-02-08 The Regents Of The University Of California 3D-exoquant method for the analysis of surface molecules and quantification of tissue-specific exosomes in biological fluids
WO2019009985A1 (en) * 2017-07-05 2019-01-10 Goetzl Edward J BIOMARKERS OF EXCITATORIC SYNAPTIC PROTEINS SPECIALIZED WITH PLASMA NEURAL EXOSOMES FOR THE PREDICTION AND STADIFICATION OF ALZHEIMER'S DISEASE

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013054534A1 (ja) * 2011-10-14 2013-04-18 国立大学法人北海道大学 アミロイドβ関連の疾患用医薬及びそのスクリーニング
JP2016535283A (ja) * 2013-10-24 2016-11-10 ナノソミックス・インコーポレイテッドＮａｎｏＳｏｍｉＸ， Ｉｎｃ． アルツハイマー病および他の神経変性障害のためのバイオマーカーおよび診断方法
WO2016088689A1 (ja) * 2014-12-05 2016-06-09 和光純薬工業株式会社 Ｔｉｍタンパク質結合担体、当該担体を用いた細胞外膜小胞及びウイルスの取得方法、除去方法、検出方法並びに当該担体を含むキット
JP2016161480A (ja) * 2015-03-04 2016-09-05 国立大学法人 千葉大学 微量の微小胞の定量、診断及びスクリーニング方法
WO2019058303A1 (en) * 2017-09-21 2019-03-28 Braindtech S.P.A. DIAGNOSTIC AND PROGNOSTIC METHODS FOR NEURODEGENERATIVE AND NEUROINFLAMMATORY DISEASES
JP2021012189A (ja) * 2019-07-04 2021-02-04 国立研究開発法人産業技術総合研究所 がん及び神経変性疾患の検出方法
WO2022250009A1 (ja) * 2021-05-26 2022-12-01 富士フイルム株式会社 レビー小体病とアルツハイマー病の鑑別を補助する方法、バイオマーカー、及び試薬キット

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* Cited by examiner, † Cited by third party
Title
AGOSTA FEDERICA ET AL.: "Myeloid microvesicles in cerebrospinal fluid are associated with myelin damage and neuronal loss in", ANNALS OF NEUROLOGY, vol. 76, no. 6, JPN6021005470, 2014, pages 813 - 825, XP055278143, ISSN: 0005092773, DOI: 10.1002/ana.24235 *
HARUKI ODAKA: "Platelet-derived extracellular vesicles are increased in sera of Alzheimer’s disease patients, as r", FEBS OPEN BIO, vol. 11, no. 3, JPN6023025566, 3 February 2021 (2021-02-03), pages 741 - 752, ISSN: 0005092775 *
HUAQI SU: "Extracellular vesicular lipids as biomarkers for the diagnosis of Alzheimer’s disease", ALZHEIMER’S DEMENT, vol. 17, no. 5, JPN6023025565, 2021, pages 053298, ISSN: 0005092776 *
NAKAI WATARU ET AL.: "A novel affinity-based method for the isolation of highly purified extracellular vesicles", SCI REP, vol. 6, JPN6021005495, 23 September 2016 (2016-09-23), pages 33935, ISSN: 0005092772 *
PULLIAM LYNN ET AL.: "Plasma neuronal exosomes serve as biomarkers of cognitive impairment in HIV infection and Alzheimer'", J NEUROVIROL, vol. 25, no. 5, JPN6021005473, 4 January 2019 (2019-01-04), pages 702 - 709, XP036925336, ISSN: 0005092774, DOI: 10.1007/s13365-018-0695-4 *
XIAOHUAN XIA: "Exosome: A novel neurotransmission modulator or non-canonical neurotransmitter?", AGEING RESEARCH REVIEWS, vol. 74, JPN6023025564, 3 January 2022 (2022-01-03), pages 101558, ISSN: 0005092777 *
下田麻子等: "細胞外ベシクルの構造特性と機能制御", DRUG DELIVERY SYSTEM, JPN6021005492, 25 March 2014 (2014-03-25), ISSN: 0005092771 *

Also Published As

Publication number Publication date
EP4067906A4 (en) 2023-04-26
US20220291242A1 (en) 2022-09-15
WO2021107154A1 (ja) 2021-06-03
JP7448831B2 (ja) 2024-03-13
EP4067906A1 (en) 2022-10-05
CN115176163A (zh) 2022-10-11

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