JPWO2021095013A5 - - Google Patents

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Publication number
JPWO2021095013A5
JPWO2021095013A5 JP2022527730A JP2022527730A JPWO2021095013A5 JP WO2021095013 A5 JPWO2021095013 A5 JP WO2021095013A5 JP 2022527730 A JP2022527730 A JP 2022527730A JP 2022527730 A JP2022527730 A JP 2022527730A JP WO2021095013 A5 JPWO2021095013 A5 JP WO2021095013A5
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JP
Japan
Prior art keywords
cells
population
cell
gene
seq
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Pending
Application number
JP2022527730A
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English (en)
Japanese (ja)
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JP2023501580A (ja
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Priority claimed from PCT/IB2020/060723 external-priority patent/WO2021095013A1/en
Publication of JP2023501580A publication Critical patent/JP2023501580A/ja
Publication of JPWO2021095013A5 publication Critical patent/JPWO2021095013A5/ja
Pending legal-status Critical Current

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JP2022527730A 2019-11-13 2020-11-13 キメラ抗原受容体を発現するt細胞を作製するための製造プロセス Pending JP2023501580A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962934991P 2019-11-13 2019-11-13
US62/934,991 2019-11-13
PCT/IB2020/060723 WO2021095013A1 (en) 2019-11-13 2020-11-13 Manufacturing process for making t cells expressing chimeric antigen receptors

Publications (2)

Publication Number Publication Date
JP2023501580A JP2023501580A (ja) 2023-01-18
JPWO2021095013A5 true JPWO2021095013A5 (zh) 2023-11-02

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ID=73598909

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022527730A Pending JP2023501580A (ja) 2019-11-13 2020-11-13 キメラ抗原受容体を発現するt細胞を作製するための製造プロセス

Country Status (14)

Country Link
US (1) US20210139850A1 (zh)
EP (1) EP4058560A1 (zh)
JP (1) JP2023501580A (zh)
KR (1) KR20220097984A (zh)
CN (1) CN114929862A (zh)
AR (1) AR120469A1 (zh)
AU (1) AU2020382219A1 (zh)
BR (1) BR112022009152A2 (zh)
CA (1) CA3158122A1 (zh)
CO (1) CO2022006008A2 (zh)
IL (1) IL292329A (zh)
MX (1) MX2022005818A (zh)
TW (1) TW202132333A (zh)
WO (1) WO2021095013A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022064428A1 (en) * 2020-09-23 2022-03-31 Crispr Therapeutics Ag Genetically engineered t cells with regnase-1 and/or tgfbrii disruption have improved functionality and persistence
EP4376873A1 (en) * 2021-07-26 2024-06-05 CRISPR Therapeutics AG Methods for manufacturing genetically engineered car-t cells
WO2023084399A1 (en) * 2021-11-09 2023-05-19 Crispr Therapeutics Ag Genetically engineered immune cells expressing masked chimeric antigen receptors specific to protein tyrosine kinase 7
US20230303713A1 (en) * 2022-03-23 2023-09-28 Crispr Therapeutics Ag Anti-cd19 car-t cells with multiple gene edits and therapeutic uses thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2800811T (pt) * 2012-05-25 2017-08-17 Univ California Métodos e composições para modificação de adn alvo dirigida por arn e para modulação dirigida por arn de transcrição
SG10201912327SA (en) * 2012-12-12 2020-02-27 Broad Inst Inc Engineering and Optimization of Improved Systems, Methods and Enzyme Compositions for Sequence Manipulation
US8697359B1 (en) * 2012-12-12 2014-04-15 The Broad Institute, Inc. CRISPR-Cas systems and methods for altering expression of gene products
KR102668549B1 (ko) * 2014-06-02 2024-05-22 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 Cd19를 표적화하는 키메라 항원 수용체
GB201418965D0 (zh) * 2014-10-24 2014-12-10 Ospedale San Raffaele And Fond Telethon
WO2016069282A1 (en) * 2014-10-31 2016-05-06 The Trustees Of The University Of Pennsylvania Altering gene expression in modified t cells and uses thereof
WO2016115179A1 (en) * 2015-01-12 2016-07-21 Massachusetts Institute Of Technology Gene editing through microfluidic delivery
WO2017222398A1 (en) * 2016-06-22 2017-12-28 Cellis Sp. Z O.O. Cellular targeted pharmaceutically active substance or label delivery system
ES2933961T3 (es) * 2016-04-15 2023-02-15 Memorial Sloan Kettering Cancer Center Células T transgénicas y composiciones de células T de receptor de antígeno quimérico y métodos relacionados
EP3452499A2 (en) * 2016-05-06 2019-03-13 Juno Therapeutics, Inc. Genetically engineered cells and methods of making the same
DE102016211884A1 (de) 2016-06-30 2018-01-04 Zf Friedrichshafen Ag Getriebe für ein Kraftfahrzeug, sowie Antriebsstrang für ein Kraftfahrzeug
EP3559214A1 (en) * 2016-12-21 2019-10-30 UCL Business PLC Therapeutic cells
US11597911B2 (en) * 2017-02-27 2023-03-07 Life Technologies Corporation Expansion of populations of T cells by the use of modified serum free media
WO2019097305A2 (en) 2017-05-12 2019-05-23 Crispr Therapeutics Ag Materials and methods for engineering cells and uses thereof in immuno-oncology
CN107392652A (zh) 2017-06-30 2017-11-24 广州市中崎商业机器股份有限公司 基于收银纸背面进行针对性广告发布的系统及方法
EP3665271A4 (en) * 2017-08-08 2021-04-28 Sangamo Therapeutics, Inc. CELL TARGETING MEDIA BY A CHEMICAL ANTIGEN RECEPTOR
CN108192927A (zh) * 2017-12-29 2018-06-22 上海海洋大学 一种瓯江彩鲤的基因编辑与过表达操作方法
CA3090416A1 (en) * 2018-02-09 2019-08-15 Immatics US, Inc. Methods for manufacturing t cells
CA3099364A1 (en) 2018-05-11 2019-11-14 Crispr Therapeutics Ag Methods and compositions for treating cancer comprising engineered t cells comprising modified chimeric antigen receptors

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