JPWO2021077000A5 - - Google Patents
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- Publication number
- JPWO2021077000A5 JPWO2021077000A5 JP2022522782A JP2022522782A JPWO2021077000A5 JP WO2021077000 A5 JPWO2021077000 A5 JP WO2021077000A5 JP 2022522782 A JP2022522782 A JP 2022522782A JP 2022522782 A JP2022522782 A JP 2022522782A JP WO2021077000 A5 JPWO2021077000 A5 JP WO2021077000A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- polypeptide
- aav
- vector system
- cargo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962916221P | 2019-10-16 | 2019-10-16 | |
| US201962916207P | 2019-10-16 | 2019-10-16 | |
| US62/916,221 | 2019-10-16 | ||
| US62/916,207 | 2019-10-16 | ||
| US202063018454P | 2020-04-30 | 2020-04-30 | |
| US63/018,454 | 2020-04-30 | ||
| US202063055252P | 2020-07-22 | 2020-07-22 | |
| US63/055,252 | 2020-07-22 | ||
| PCT/US2020/056133 WO2021077000A1 (en) | 2019-10-16 | 2020-10-16 | Engineered muscle targeting compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022551986A JP2022551986A (ja) | 2022-12-14 |
| JPWO2021077000A5 true JPWO2021077000A5 (ko) | 2023-10-18 |
Family
ID=75538392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022522782A Pending JP2022551986A (ja) | 2019-10-16 | 2020-10-16 | 修飾筋肉標的化組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20220340929A1 (ko) |
| EP (1) | EP4045637A4 (ko) |
| JP (1) | JP2022551986A (ko) |
| CN (1) | CN115175991A (ko) |
| AU (1) | AU2020368539A1 (ko) |
| CA (1) | CA3153902A1 (ko) |
| WO (1) | WO2021077000A1 (ko) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4244209A1 (en) | 2020-11-11 | 2023-09-20 | European Molecular Biology Laboratory | Modified viral particles for gene therapy |
| US20240197918A1 (en) * | 2021-04-23 | 2024-06-20 | Locanabio, Inc. | Tissue-targeted modified aav capsids and methods of use thereof |
| AR125406A1 (es) * | 2021-04-23 | 2023-07-12 | Univ Pennsylvania | Nuevas composiciones con motivos selectivos para el cerebro y composiciones que las contienen |
| WO2022226375A1 (en) * | 2021-04-23 | 2022-10-27 | Locanabio, Inc. | Tissue-targeted modified aav capsids and methods of use thereof |
| AU2022324116A1 (en) * | 2021-08-05 | 2024-03-14 | Massachusetts Institute Of Technology | Engineered muscle targeting compositions |
| AU2022325165A1 (en) * | 2021-08-05 | 2024-01-18 | Insmed Incorporated | Adeno-associated virus particles and methods of use thereof |
| AU2022334454A1 (en) * | 2021-08-24 | 2024-03-14 | Prime Medicine, Inc. | Genome editing compositions and methods for treatment of retinopathy |
| EP4399316A1 (en) * | 2021-09-08 | 2024-07-17 | The Broad Institute, Inc. | Engineered muscle and central nervous system compositions |
| CN118202060A (zh) | 2021-10-05 | 2024-06-14 | 再生生物股份有限公司 | 用于重组aav生产的组合物和方法 |
| WO2023060113A1 (en) | 2021-10-05 | 2023-04-13 | Regenxbio Inc. | Compositions and methods for recombinant aav production |
| AU2022360985A1 (en) * | 2021-10-05 | 2024-05-16 | Massachusetts Institute Of Technology | Engineered cardiac muscle compositions |
| WO2023111351A1 (en) * | 2021-12-17 | 2023-06-22 | Christian Kupatt | Aav vectors for gene therapy in endothelial cells |
| WO2023148617A1 (en) * | 2022-02-01 | 2023-08-10 | The Broad Institute, Inc. | Adeno-associated viral vectors and uses thereof |
| WO2023183860A1 (en) * | 2022-03-23 | 2023-09-28 | University Of Delaware | Engineered extracellular vesicles for targeted drug delivery to muscle |
| CN116870198B (zh) * | 2023-09-06 | 2023-11-28 | 中国农业大学 | 一种调节骨骼肌损伤修复的方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002523105A (ja) | 1998-08-27 | 2002-07-30 | アバンテイス・フアルマ・エス・アー | 異種遺伝子の運搬用の標的化アデノウイルスベクター |
| DE19933719A1 (de) | 1999-07-19 | 2001-01-25 | Medigene Ag | Strukturprotein in Adeno-assoziiertem Virus mit veränderten chromatographischen Eigenschaften, seine Herstellung und Verwendung |
| US7749492B2 (en) * | 2001-01-05 | 2010-07-06 | Nationwide Children's Hospital, Inc. | AAV vectors and methods |
| US6962815B2 (en) | 2001-01-05 | 2005-11-08 | Children's Hopital Inc. | AAV2 vectors and methods |
| US20040142325A1 (en) * | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
| WO2005075506A1 (en) * | 2004-01-09 | 2005-08-18 | The Scripps Research Institute | Identification of endogenous trimerization domains in the adenovirus fiber protein that allow detargeting and retargeting of viral vectors |
| US8476418B2 (en) | 2009-05-28 | 2013-07-02 | Deutsches Krebsforschungszentrum | Modified AAV capsid polypeptides |
| WO2015116568A2 (en) * | 2014-01-28 | 2015-08-06 | University Of Miami | Muscle cell-targeting nanoparticles for vaccination and nucleic acid delivery, and methods of production and use thereof |
| WO2015191508A1 (en) * | 2014-06-09 | 2015-12-17 | Voyager Therapeutics, Inc. | Chimeric capsids |
| CA2988486A1 (en) * | 2015-06-10 | 2016-12-15 | Association Institut De Myologie | Combined therapy for duchenne muscular dystrophy |
| EP3384034B1 (en) | 2015-12-02 | 2020-07-08 | The Board of Trustees of the Leland Stanford Junior University | Novel recombinant adeno-associated virus capsids with enhanced human skeletal muscle tropism |
| CA3097375A1 (en) * | 2018-04-27 | 2019-10-31 | Universitat Heidelberg | Modified aav capsid polypeptides for treatment of muscular diseases |
| CN114729384A (zh) * | 2019-09-12 | 2022-07-08 | 博德研究所 | 工程化腺相关病毒衣壳 |
| CN114787179A (zh) * | 2019-10-10 | 2022-07-22 | 坚固生物科技公司 | 经修饰的aav衣壳及其用途 |
-
2020
- 2020-10-16 JP JP2022522782A patent/JP2022551986A/ja active Pending
- 2020-10-16 US US17/764,509 patent/US20220340929A1/en active Pending
- 2020-10-16 WO PCT/US2020/056133 patent/WO2021077000A1/en unknown
- 2020-10-16 CA CA3153902A patent/CA3153902A1/en active Pending
- 2020-10-16 CN CN202080084923.3A patent/CN115175991A/zh active Pending
- 2020-10-16 EP EP20877004.0A patent/EP4045637A4/en active Pending
- 2020-10-16 AU AU2020368539A patent/AU2020368539A1/en active Pending
-
2022
- 2022-03-29 US US17/707,940 patent/US11920150B2/en active Active
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