JPWO2021050948A5 - - Google Patents

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Publication number
JPWO2021050948A5
JPWO2021050948A5 JP2022516320A JP2022516320A JPWO2021050948A5 JP WO2021050948 A5 JPWO2021050948 A5 JP WO2021050948A5 JP 2022516320 A JP2022516320 A JP 2022516320A JP 2022516320 A JP2022516320 A JP 2022516320A JP WO2021050948 A5 JPWO2021050948 A5 JP WO2021050948A5
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JP
Japan
Prior art keywords
item
nucleic acid
recombinant nucleic
domain
sequence
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022516320A
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English (en)
Japanese (ja)
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JP2022548866A (ja
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Priority claimed from PCT/US2020/050503 external-priority patent/WO2021050948A1/en
Publication of JP2022548866A publication Critical patent/JP2022548866A/ja
Publication of JPWO2021050948A5 publication Critical patent/JPWO2021050948A5/ja
Pending legal-status Critical Current

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JP2022516320A 2019-09-12 2020-09-11 融合タンパク質を用いたtcrリプログラミングのための組成物及び方法 Pending JP2022548866A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962899563P 2019-09-12 2019-09-12
US62/899,563 2019-09-12
US202062971682P 2020-02-07 2020-02-07
US62/971,682 2020-02-07
PCT/US2020/050503 WO2021050948A1 (en) 2019-09-12 2020-09-11 Compositions and methods for tcr reprogramming using fusion proteins

Publications (2)

Publication Number Publication Date
JP2022548866A JP2022548866A (ja) 2022-11-22
JPWO2021050948A5 true JPWO2021050948A5 (ko) 2023-09-20

Family

ID=74866684

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022516320A Pending JP2022548866A (ja) 2019-09-12 2020-09-11 融合タンパク質を用いたtcrリプログラミングのための組成物及び方法

Country Status (10)

Country Link
EP (1) EP4028033A4 (ko)
JP (1) JP2022548866A (ko)
KR (1) KR20220078607A (ko)
CN (1) CN114828862A (ko)
AU (1) AU2020344628A1 (ko)
BR (1) BR112022004458A2 (ko)
CA (1) CA3154287A1 (ko)
IL (1) IL291236A (ko)
MX (1) MX2022002984A (ko)
WO (1) WO2021050948A1 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023091420A2 (en) * 2021-11-16 2023-05-25 TCR2 Therapeutics Inc. Compositions and methods for t cell engineering
WO2023133296A2 (en) * 2022-01-07 2023-07-13 Sorrento Therapeutics, Inc. Engineered pd-l1-targeting gamma delta t cell receptors
WO2024039576A2 (en) * 2022-08-19 2024-02-22 Memorial Sloan-Kettering Cancer Center T cell receptors targeting ras mutations and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9181527B2 (en) * 2009-10-29 2015-11-10 The Trustees Of Dartmouth College T cell receptor-deficient T cell compositions
SG11201401030WA (en) * 2011-10-28 2014-04-28 Regeneron Pharma Genetically modified t cell receptor mice
US11421013B2 (en) * 2015-10-23 2022-08-23 Eureka Therapeutics, Inc. Antibody/T-cell receptor chimeric constructs and uses thereof
GB201604494D0 (en) * 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Transfected T-Cells and T-Cell receptors for use in immunotherapy against cancers
WO2018067993A1 (en) * 2016-10-07 2018-04-12 TCR2 Therapeutics Inc. Compositions and methods for t-cell receptors reprogramming using fusion proteins
JP7291396B2 (ja) * 2016-11-22 2023-06-15 ティーシーアール2 セラピューティクス インク. 融合タンパク質を用いたtcrの再プログラミングのための組成物及び方法
CA3047999A1 (en) * 2016-12-21 2018-06-28 TCR2 Therapeutics Inc. Engineered t cells for the treatment of cancer
WO2018232020A1 (en) * 2017-06-13 2018-12-20 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using fusion proteins
US11738047B2 (en) * 2017-12-12 2023-08-29 The Trustees Of The University Of Pennsylvania Genetically modified immune cells targeting NY-ESO-1 and methods of use thereof
WO2019133443A1 (en) * 2017-12-28 2019-07-04 Janux Therapeutics, Inc. Modified t cell receptors
EP3765039A4 (en) * 2018-03-09 2021-12-08 TCR2 Therapeutics Inc. COMPOSITIONS AND METHODS FOR REPROGRAMMING TCR USING FUSION PROTEINS

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