JPWO2021050948A5 - - Google Patents
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- Publication number
- JPWO2021050948A5 JPWO2021050948A5 JP2022516320A JP2022516320A JPWO2021050948A5 JP WO2021050948 A5 JPWO2021050948 A5 JP WO2021050948A5 JP 2022516320 A JP2022516320 A JP 2022516320A JP 2022516320 A JP2022516320 A JP 2022516320A JP WO2021050948 A5 JPWO2021050948 A5 JP WO2021050948A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- nucleic acid
- recombinant nucleic
- domain
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962899563P | 2019-09-12 | 2019-09-12 | |
US62/899,563 | 2019-09-12 | ||
US202062971682P | 2020-02-07 | 2020-02-07 | |
US62/971,682 | 2020-02-07 | ||
PCT/US2020/050503 WO2021050948A1 (en) | 2019-09-12 | 2020-09-11 | Compositions and methods for tcr reprogramming using fusion proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022548866A JP2022548866A (ja) | 2022-11-22 |
JPWO2021050948A5 true JPWO2021050948A5 (ko) | 2023-09-20 |
Family
ID=74866684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2022516320A Pending JP2022548866A (ja) | 2019-09-12 | 2020-09-11 | 融合タンパク質を用いたtcrリプログラミングのための組成物及び方法 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP4028033A4 (ko) |
JP (1) | JP2022548866A (ko) |
KR (1) | KR20220078607A (ko) |
CN (1) | CN114828862A (ko) |
AU (1) | AU2020344628A1 (ko) |
BR (1) | BR112022004458A2 (ko) |
CA (1) | CA3154287A1 (ko) |
IL (1) | IL291236A (ko) |
MX (1) | MX2022002984A (ko) |
WO (1) | WO2021050948A1 (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023091420A2 (en) * | 2021-11-16 | 2023-05-25 | TCR2 Therapeutics Inc. | Compositions and methods for t cell engineering |
WO2023133296A2 (en) * | 2022-01-07 | 2023-07-13 | Sorrento Therapeutics, Inc. | Engineered pd-l1-targeting gamma delta t cell receptors |
WO2024039576A2 (en) * | 2022-08-19 | 2024-02-22 | Memorial Sloan-Kettering Cancer Center | T cell receptors targeting ras mutations and uses thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9181527B2 (en) * | 2009-10-29 | 2015-11-10 | The Trustees Of Dartmouth College | T cell receptor-deficient T cell compositions |
SG11201401030WA (en) * | 2011-10-28 | 2014-04-28 | Regeneron Pharma | Genetically modified t cell receptor mice |
US11421013B2 (en) * | 2015-10-23 | 2022-08-23 | Eureka Therapeutics, Inc. | Antibody/T-cell receptor chimeric constructs and uses thereof |
GB201604494D0 (en) * | 2016-03-16 | 2016-04-27 | Immatics Biotechnologies Gmbh | Transfected T-Cells and T-Cell receptors for use in immunotherapy against cancers |
WO2018067993A1 (en) * | 2016-10-07 | 2018-04-12 | TCR2 Therapeutics Inc. | Compositions and methods for t-cell receptors reprogramming using fusion proteins |
JP7291396B2 (ja) * | 2016-11-22 | 2023-06-15 | ティーシーアール2 セラピューティクス インク. | 融合タンパク質を用いたtcrの再プログラミングのための組成物及び方法 |
CA3047999A1 (en) * | 2016-12-21 | 2018-06-28 | TCR2 Therapeutics Inc. | Engineered t cells for the treatment of cancer |
WO2018232020A1 (en) * | 2017-06-13 | 2018-12-20 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
US11738047B2 (en) * | 2017-12-12 | 2023-08-29 | The Trustees Of The University Of Pennsylvania | Genetically modified immune cells targeting NY-ESO-1 and methods of use thereof |
WO2019133443A1 (en) * | 2017-12-28 | 2019-07-04 | Janux Therapeutics, Inc. | Modified t cell receptors |
EP3765039A4 (en) * | 2018-03-09 | 2021-12-08 | TCR2 Therapeutics Inc. | COMPOSITIONS AND METHODS FOR REPROGRAMMING TCR USING FUSION PROTEINS |
-
2020
- 2020-09-11 JP JP2022516320A patent/JP2022548866A/ja active Pending
- 2020-09-11 CA CA3154287A patent/CA3154287A1/en active Pending
- 2020-09-11 KR KR1020227012166A patent/KR20220078607A/ko unknown
- 2020-09-11 AU AU2020344628A patent/AU2020344628A1/en not_active Abandoned
- 2020-09-11 BR BR112022004458A patent/BR112022004458A2/pt not_active Application Discontinuation
- 2020-09-11 WO PCT/US2020/050503 patent/WO2021050948A1/en unknown
- 2020-09-11 MX MX2022002984A patent/MX2022002984A/es unknown
- 2020-09-11 CN CN202080079086.5A patent/CN114828862A/zh active Pending
- 2020-09-11 EP EP20862242.3A patent/EP4028033A4/en not_active Withdrawn
-
2022
- 2022-03-09 IL IL291236A patent/IL291236A/en unknown
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