JPWO2020264019A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020264019A5 JPWO2020264019A5 JP2021576554A JP2021576554A JPWO2020264019A5 JP WO2020264019 A5 JPWO2020264019 A5 JP WO2020264019A5 JP 2021576554 A JP2021576554 A JP 2021576554A JP 2021576554 A JP2021576554 A JP 2021576554A JP WO2020264019 A5 JPWO2020264019 A5 JP WO2020264019A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- hspcs
- mature
- increased
- pluripotent stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962865835P | 2019-06-24 | 2019-06-24 | |
| US62/865,835 | 2019-06-24 | ||
| PCT/US2020/039414 WO2020264019A1 (en) | 2019-06-24 | 2020-06-24 | Bcl11b overexpression to enhance human thymopoiesis and t cell function |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022539032A JP2022539032A (ja) | 2022-09-07 |
| JP2022539032A5 JP2022539032A5 (https=) | 2023-07-03 |
| JPWO2020264019A5 true JPWO2020264019A5 (https=) | 2023-07-03 |
Family
ID=71842851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021576554A Pending JP2022539032A (ja) | 2019-06-24 | 2020-06-24 | ヒト胸腺細胞形成およびt細胞機能を強化するためのbcl11b過剰発現 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220347222A1 (https=) |
| EP (1) | EP3986427A1 (https=) |
| JP (1) | JP2022539032A (https=) |
| KR (1) | KR20220042353A (https=) |
| CN (1) | CN114828876A (https=) |
| AU (1) | AU2020301413A1 (https=) |
| CA (1) | CA3144640A1 (https=) |
| WO (1) | WO2020264019A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112574952B (zh) * | 2019-09-30 | 2025-04-15 | 英基生物医药(香港)有限公司 | 一种工程化人体免疫细胞、其制备方法及应用 |
| US12365871B2 (en) | 2020-04-28 | 2025-07-22 | Lyell Immunopharma, Inc. | Methods for culturing cells |
| FR3130843A1 (fr) * | 2021-12-21 | 2023-06-23 | Universite Claude Bernard Lyon 1 | Cellule progéniteur des lymphocytes T exprimant de manière régulée un transgène d’intérêt |
| WO2025038494A1 (en) * | 2023-08-11 | 2025-02-20 | Tune Therapeutics, Inc. | Compositions, systems, and methods for lymphoid cell differentiation using targeted gene activation |
| WO2025097004A1 (en) * | 2023-11-02 | 2025-05-08 | Regents Of The University Of Minnesota | Modulation of hematopoietic cells using bcl11b |
| CN118374444A (zh) * | 2024-05-24 | 2024-07-23 | 中国人民解放军军事科学院军事医学研究院 | 一种利用骨髓类器官体外生产人血细胞的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2735800C (en) * | 2008-09-03 | 2018-05-01 | Angioblast Systems, Inc. | Expansion of haemopoietic precursors |
| US8465743B2 (en) | 2009-10-01 | 2013-06-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| WO2012096974A1 (en) * | 2011-01-10 | 2012-07-19 | The Board Of Trustees Of The Leland Stanford Junior University | Enhancement of allogeneic hematopoietic stem cell transplantation |
| WO2013059593A1 (en) | 2011-10-20 | 2013-04-25 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-cd22 chimeric antigen receptors |
| AU2014248119B2 (en) * | 2013-04-03 | 2019-06-20 | Memorial Sloan-Kettering Cancer Center | Effective generation of tumor-targeted T-cells derived from pluripotent stem cells |
| MX2018005274A (es) * | 2015-10-30 | 2019-09-19 | The Regents Of The Universtiy Of California | Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t. |
| JP7049261B2 (ja) * | 2016-04-08 | 2022-04-06 | ザ ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント | 幹細胞および/または前駆細胞からt前駆細胞を作製する方法ならびに該t前駆細胞の使用 |
| IL268641B2 (en) * | 2017-02-13 | 2024-10-01 | Assist Publique Hopitaux Paris Aphp | Method for generating t cells progenitors |
| CA3083779A1 (en) * | 2017-12-22 | 2019-06-27 | Fate Therapeutics, Inc. | Enhanced immune effector cells and use thereof |
-
2020
- 2020-06-24 AU AU2020301413A patent/AU2020301413A1/en active Pending
- 2020-06-24 JP JP2021576554A patent/JP2022539032A/ja active Pending
- 2020-06-24 KR KR1020227002438A patent/KR20220042353A/ko active Pending
- 2020-06-24 CN CN202080060106.4A patent/CN114828876A/zh active Pending
- 2020-06-24 WO PCT/US2020/039414 patent/WO2020264019A1/en not_active Ceased
- 2020-06-24 CA CA3144640A patent/CA3144640A1/en active Pending
- 2020-06-24 US US17/620,603 patent/US20220347222A1/en active Pending
- 2020-06-24 EP EP20747270.5A patent/EP3986427A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7216045B2 (ja) | 養子t細胞療法のためのセントラルメモリーt細胞 | |
| US20250002850A1 (en) | Methods for manufacturing t cells expressing of chimeric antigen receptors and other receptors | |
| JP7292213B2 (ja) | Crispr/cpf1を用いる、t細胞における遺伝子編集のための組成物および方法 | |
| RU2744603C2 (ru) | Композиции, повышающие число копий вектора (чкв), и способы их применения | |
| JP7206190B2 (ja) | 遺伝的に修飾されたtリンパ球 | |
| JP2024045128A5 (https=) | ||
| AU2016349482A1 (en) | Methods for preparing cells for adoptive T cell therapy | |
| BR112020001132A2 (pt) | interruptor modulável para seleção de células doadoras modificadas | |
| WO2017071173A1 (zh) | 经il-12/cd62l融合蛋白改造的肿瘤治疗剂及其制法和用途 | |
| CN102027104A (zh) | 含有细胞因子诱导杀伤细胞的细胞群的制造方法 | |
| TW202102667A (zh) | 用於擴增和分化供過繼性細胞治療之t淋巴細胞和天然殺手(nk)細胞之方法 | |
| JPWO2020264019A5 (https=) | ||
| CN114317445B (zh) | 扩增t细胞的方法及其应用 | |
| CN109293781A (zh) | 嵌合抗原受体及其基因和重组表达载体、cd19-cd20双靶向性的t细胞及其应用 | |
| JP5911810B2 (ja) | 制御性t細胞の製造方法 | |
| US20240316106A1 (en) | Methods for generating primary immune cells | |
| Kawai et al. | Feeder-free generation of CD4 single-positive helper T cells from human iPSCs via stage-specific modulation of Notch and TCR Signaling | |
| JPWO2021209759A5 (https=) | ||
| JP6855579B2 (ja) | T細胞を得る方法及び使用 | |
| WO1996017627A2 (en) | System for the maintenance, growth and differentiation of human and non-human primate pluripotent stem, progenitor and mature bone marrow cells | |
| CN114369621B (zh) | 一种基因生物制剂及其制备方法和应用 | |
| AU2020203550A1 (en) | Central Memory T Cells for Adoptive T Cell Therapy | |
| US20250325583A1 (en) | Engineered progenitor cells and methods of use | |
| HK40059960A (en) | Central memory t cells for adoptive t cell therapy | |
| CN117625544A (zh) | 基于代谢调控的改造的效应t细胞及其改造方法 |