JPWO2020264019A5 - - Google Patents

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Publication number
JPWO2020264019A5
JPWO2020264019A5 JP2021576554A JP2021576554A JPWO2020264019A5 JP WO2020264019 A5 JPWO2020264019 A5 JP WO2020264019A5 JP 2021576554 A JP2021576554 A JP 2021576554A JP 2021576554 A JP2021576554 A JP 2021576554A JP WO2020264019 A5 JPWO2020264019 A5 JP WO2020264019A5
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JP
Japan
Prior art keywords
cells
hspcs
mature
increased
pluripotent stem
Prior art date
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Pending
Application number
JP2021576554A
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English (en)
Japanese (ja)
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JP2022539032A5 (https=
JP2022539032A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/039414 external-priority patent/WO2020264019A1/en
Publication of JP2022539032A publication Critical patent/JP2022539032A/ja
Publication of JP2022539032A5 publication Critical patent/JP2022539032A5/ja
Publication of JPWO2020264019A5 publication Critical patent/JPWO2020264019A5/ja
Pending legal-status Critical Current

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JP2021576554A 2019-06-24 2020-06-24 ヒト胸腺細胞形成およびt細胞機能を強化するためのbcl11b過剰発現 Pending JP2022539032A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962865835P 2019-06-24 2019-06-24
US62/865,835 2019-06-24
PCT/US2020/039414 WO2020264019A1 (en) 2019-06-24 2020-06-24 Bcl11b overexpression to enhance human thymopoiesis and t cell function

Publications (3)

Publication Number Publication Date
JP2022539032A JP2022539032A (ja) 2022-09-07
JP2022539032A5 JP2022539032A5 (https=) 2023-07-03
JPWO2020264019A5 true JPWO2020264019A5 (https=) 2023-07-03

Family

ID=71842851

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021576554A Pending JP2022539032A (ja) 2019-06-24 2020-06-24 ヒト胸腺細胞形成およびt細胞機能を強化するためのbcl11b過剰発現

Country Status (8)

Country Link
US (1) US20220347222A1 (https=)
EP (1) EP3986427A1 (https=)
JP (1) JP2022539032A (https=)
KR (1) KR20220042353A (https=)
CN (1) CN114828876A (https=)
AU (1) AU2020301413A1 (https=)
CA (1) CA3144640A1 (https=)
WO (1) WO2020264019A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112574952B (zh) * 2019-09-30 2025-04-15 英基生物医药(香港)有限公司 一种工程化人体免疫细胞、其制备方法及应用
US12365871B2 (en) 2020-04-28 2025-07-22 Lyell Immunopharma, Inc. Methods for culturing cells
FR3130843A1 (fr) * 2021-12-21 2023-06-23 Universite Claude Bernard Lyon 1 Cellule progéniteur des lymphocytes T exprimant de manière régulée un transgène d’intérêt
WO2025038494A1 (en) * 2023-08-11 2025-02-20 Tune Therapeutics, Inc. Compositions, systems, and methods for lymphoid cell differentiation using targeted gene activation
WO2025097004A1 (en) * 2023-11-02 2025-05-08 Regents Of The University Of Minnesota Modulation of hematopoietic cells using bcl11b
CN118374444A (zh) * 2024-05-24 2024-07-23 中国人民解放军军事科学院军事医学研究院 一种利用骨髓类器官体外生产人血细胞的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2735800C (en) * 2008-09-03 2018-05-01 Angioblast Systems, Inc. Expansion of haemopoietic precursors
US8465743B2 (en) 2009-10-01 2013-06-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer
PH12013501201A1 (en) 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
WO2012096974A1 (en) * 2011-01-10 2012-07-19 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of allogeneic hematopoietic stem cell transplantation
WO2013059593A1 (en) 2011-10-20 2013-04-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-cd22 chimeric antigen receptors
AU2014248119B2 (en) * 2013-04-03 2019-06-20 Memorial Sloan-Kettering Cancer Center Effective generation of tumor-targeted T-cells derived from pluripotent stem cells
MX2018005274A (es) * 2015-10-30 2019-09-19 The Regents Of The Universtiy Of California Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t.
JP7049261B2 (ja) * 2016-04-08 2022-04-06 ザ ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント 幹細胞および/または前駆細胞からt前駆細胞を作製する方法ならびに該t前駆細胞の使用
IL268641B2 (en) * 2017-02-13 2024-10-01 Assist Publique Hopitaux Paris Aphp Method for generating t cells progenitors
CA3083779A1 (en) * 2017-12-22 2019-06-27 Fate Therapeutics, Inc. Enhanced immune effector cells and use thereof

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