JPWO2020245169A5 - - Google Patents
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- Publication number
- JPWO2020245169A5 JPWO2020245169A5 JP2021571874A JP2021571874A JPWO2020245169A5 JP WO2020245169 A5 JPWO2020245169 A5 JP WO2020245169A5 JP 2021571874 A JP2021571874 A JP 2021571874A JP 2021571874 A JP2021571874 A JP 2021571874A JP WO2020245169 A5 JPWO2020245169 A5 JP WO2020245169A5
- Authority
- JP
- Japan
- Prior art keywords
- vector
- seq
- promoter
- aav9
- mpz
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1907882.3 | 2019-06-03 | ||
| GBGB1907882.3A GB201907882D0 (en) | 2019-06-03 | 2019-06-03 | Methods |
| PCT/EP2020/065312 WO2020245169A1 (en) | 2019-06-03 | 2020-06-03 | Aav vectors with myelin protein zero promoter and uses thereof for treating schwann cell-associated diseases like charcot-marie-tooth disease |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022535412A JP2022535412A (ja) | 2022-08-08 |
| JPWO2020245169A5 true JPWO2020245169A5 (https=) | 2023-06-02 |
| JP2022535412A5 JP2022535412A5 (https=) | 2023-06-02 |
| JP7692369B2 JP7692369B2 (ja) | 2025-06-13 |
Family
ID=67385825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021571874A Active JP7692369B2 (ja) | 2019-06-03 | 2020-06-03 | シャルコー・マリー・トゥース病のようなシュワン細胞関連疾患を治療するためのミエリンタンパク質ゼロのプロモーターを含むａａｖベクター及びその使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US12582725B2 (https=) |
| EP (1) | EP3976800A1 (https=) |
| JP (1) | JP7692369B2 (https=) |
| KR (1) | KR20220016485A (https=) |
| CN (1) | CN114026242A (https=) |
| AU (1) | AU2020288605A1 (https=) |
| BR (1) | BR112021024285A2 (https=) |
| CA (1) | CA3142211A1 (https=) |
| CL (1) | CL2021003201A1 (https=) |
| CO (1) | CO2021016487A2 (https=) |
| EA (1) | EA202290001A1 (https=) |
| GB (1) | GB201907882D0 (https=) |
| IL (1) | IL288462A (https=) |
| MX (1) | MX2021014789A (https=) |
| SG (1) | SG11202112889VA (https=) |
| WO (1) | WO2020245169A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240076665A1 (en) * | 2020-12-22 | 2024-03-07 | Wisconsin Alumni Research Foundation | Regulatory elements for schwann cell-specific gene expression |
| CA3234702A1 (en) | 2021-10-07 | 2023-04-13 | Research Institute At Nationwide Children's Hospital | Products and methods for myelin protein zero silencing and treating cmt1b disease |
| JP2025502269A (ja) * | 2022-01-13 | 2025-01-24 | ツールゲン インコーポレイテッド | シュワン細胞特異的プロモーター |
| GB202303495D0 (en) * | 2023-03-09 | 2023-04-26 | Ucl Business Ltd | Therapy for charcot-marie-tooth disease |
| WO2025105734A1 (ko) * | 2023-11-15 | 2025-05-22 | 주식회사 카인사이언스 | 탈수초 질환 치료용 펩타이드 및 이의 용도 |
| WO2025174135A1 (ko) * | 2024-02-16 | 2025-08-21 | 주식회사 엣진 | 샤르코-마리-투스 질환 치료를 위한 징크 핑거 단백질 및 이를 발현시키는 방법 |
| CN118291543A (zh) * | 2024-02-29 | 2024-07-05 | 神拓生物技术(杭州)有限公司 | 一种二型神经纤维瘤基因治疗的慢病毒载体及其应用 |
| KR20260001543A (ko) * | 2024-06-25 | 2026-01-06 | 연세대학교 산학협력단 | 바이러스 벡터를 포함한 난청 치료용 조성물 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL210751B1 (pl) | 2006-09-12 | 2012-02-29 | Anna Jurewicz | Izolowany fragment białka Nogo-A, jego zastosowanie oraz sposób diagnozowania oraz leczenia stwardnienia rozsianego i polineuropatii zapalno-demielinizacyjnej |
| US20090018031A1 (en) | 2006-12-07 | 2009-01-15 | Switchgear Genomics | Transcriptional regulatory elements of biological pathways tools, and methods |
| US20090215178A1 (en) | 2008-02-22 | 2009-08-27 | Zequn Tang | Methods to enhance the stability and homogeneity of transgene expression in clonal cell lines |
| CA2730785A1 (en) | 2008-07-16 | 2010-01-21 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of gm98 (mrf) in remyelination |
| AU2010289419A1 (en) | 2009-09-02 | 2012-03-29 | The University Of Chicago | Methods and systems for inducible ablation of neural cells |
| EP2826860B1 (en) | 2010-04-23 | 2018-08-22 | University of Massachusetts | CNS targeting AAV vectors and methods of use thereof |
| AU2012258558A1 (en) | 2011-05-26 | 2013-05-02 | Biogen Ma Inc. | Methods of treating multiple sclerosis and preserving and/or increasing myelin content |
| DK2820042T3 (da) | 2012-02-29 | 2019-10-28 | Baxalta GmbH | Igg-stimuleret remyelinisering af perifere nerver |
| AU2013243948A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| US9644215B2 (en) * | 2013-04-12 | 2017-05-09 | The General Hospital Corporation | AAV1-caspase gene therapy induced pyroptosis for the treatment of tumors |
| WO2015140351A1 (en) | 2014-03-21 | 2015-09-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for enhancing myelination |
| EP2933335A1 (en) * | 2014-04-18 | 2015-10-21 | Genethon | A method of treating peripheral neuropathies and motor neuron diseases |
| US10675382B2 (en) | 2014-09-12 | 2020-06-09 | Kyoto Prefectural Public University Corporation | Schwann cells and method for preparing same |
| EP3286318A2 (en) | 2015-04-22 | 2018-02-28 | Mina Therapeutics Limited | Sarna compositions and methods of use |
| RU2766200C1 (ru) | 2015-10-01 | 2022-02-09 | Хит Байолоджикс, Инк. | Композиции и способы для соединения внеклеточных доменов типа i и типа ii в качестве гетерологичных химерных белков |
| JP7064197B2 (ja) | 2016-09-23 | 2022-05-10 | 国立大学法人大阪大学 | シュワン細胞分化促進剤及び末梢神経再生促進剤 |
| EP3526320A1 (en) | 2016-10-14 | 2019-08-21 | President and Fellows of Harvard College | Aav delivery of nucleobase editors |
| WO2018088694A2 (ko) | 2016-11-14 | 2018-05-17 | 주식회사 툴젠 | 인위적으로 조작된 sc 기능 조절 시스템 |
| WO2018106753A1 (en) * | 2016-12-07 | 2018-06-14 | The General Hospital Corporation | Methods and compositions relating the treatment of tumors |
| EP3635121A1 (en) | 2017-06-02 | 2020-04-15 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Viral vector combining gene therapy and genome editing approaches for gene therapy of genetic disorders |
| AU2018345772B2 (en) * | 2017-10-02 | 2025-04-17 | Research Institute At Nationwide Children's Hospital | MiRNA detargeting system for tissue specific interference |
| AU2018351528B2 (en) * | 2017-10-20 | 2025-02-27 | Research Institute At Nationwide Children's Hospital | Methods and materials for NT-3 gene therapy |
| IL299762A (en) | 2020-07-13 | 2023-03-01 | Univ Pennsylvania | Useful preparations for the treatment of Charcot-Marietot disease |
-
2019
- 2019-06-03 GB GBGB1907882.3A patent/GB201907882D0/en not_active Ceased
-
2020
- 2020-06-03 SG SG11202112889VA patent/SG11202112889VA/en unknown
- 2020-06-03 BR BR112021024285A patent/BR112021024285A2/pt unknown
- 2020-06-03 WO PCT/EP2020/065312 patent/WO2020245169A1/en not_active Ceased
- 2020-06-03 JP JP2021571874A patent/JP7692369B2/ja active Active
- 2020-06-03 MX MX2021014789A patent/MX2021014789A/es unknown
- 2020-06-03 CA CA3142211A patent/CA3142211A1/en active Pending
- 2020-06-03 CN CN202080040867.3A patent/CN114026242A/zh active Pending
- 2020-06-03 KR KR1020217042344A patent/KR20220016485A/ko not_active Ceased
- 2020-06-03 US US17/616,006 patent/US12582725B2/en active Active
- 2020-06-03 EP EP20732138.1A patent/EP3976800A1/en active Pending
- 2020-06-03 AU AU2020288605A patent/AU2020288605A1/en active Pending
- 2020-06-03 EA EA202290001A patent/EA202290001A1/ru unknown
-
2021
- 2021-11-28 IL IL288462A patent/IL288462A/en unknown
- 2021-12-01 CL CL2021003201A patent/CL2021003201A1/es unknown
- 2021-12-02 CO CONC2021/0016487A patent/CO2021016487A2/es unknown
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