JPWO2020227475A5 - - Google Patents

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Publication number
JPWO2020227475A5
JPWO2020227475A5 JP2021566149A JP2021566149A JPWO2020227475A5 JP WO2020227475 A5 JPWO2020227475 A5 JP WO2020227475A5 JP 2021566149 A JP2021566149 A JP 2021566149A JP 2021566149 A JP2021566149 A JP 2021566149A JP WO2020227475 A5 JPWO2020227475 A5 JP WO2020227475A5
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JP
Japan
Prior art keywords
cell
polypeptide
item
domain
natural
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Pending
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JP2021566149A
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English (en)
Japanese (ja)
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JP2022532556A (ja
JP2022532556A5 (https=
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Priority claimed from PCT/US2020/031781 external-priority patent/WO2020227475A1/en
Publication of JP2022532556A publication Critical patent/JP2022532556A/ja
Publication of JPWO2020227475A5 publication Critical patent/JPWO2020227475A5/ja
Publication of JP2022532556A5 publication Critical patent/JP2022532556A5/ja
Priority to JP2025020891A priority Critical patent/JP2025081414A/ja
Pending legal-status Critical Current

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JP2021566149A 2019-05-08 2020-05-07 Cll-1標的免疫療法 Pending JP2022532556A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025020891A JP2025081414A (ja) 2019-05-08 2025-02-12 Cll-1標的免疫療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962845306P 2019-05-08 2019-05-08
US62/845,306 2019-05-08
PCT/US2020/031781 WO2020227475A1 (en) 2019-05-08 2020-05-07 Cll-1 targeted immunotherapies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025020891A Division JP2025081414A (ja) 2019-05-08 2025-02-12 Cll-1標的免疫療法

Publications (3)

Publication Number Publication Date
JP2022532556A JP2022532556A (ja) 2022-07-15
JPWO2020227475A5 true JPWO2020227475A5 (https=) 2023-05-15
JP2022532556A5 JP2022532556A5 (https=) 2023-05-15

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ID=73051177

Family Applications (2)

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JP2021566149A Pending JP2022532556A (ja) 2019-05-08 2020-05-07 Cll-1標的免疫療法
JP2025020891A Pending JP2025081414A (ja) 2019-05-08 2025-02-12 Cll-1標的免疫療法

Family Applications After (1)

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JP2025020891A Pending JP2025081414A (ja) 2019-05-08 2025-02-12 Cll-1標的免疫療法

Country Status (13)

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US (2) US12421315B2 (https=)
EP (1) EP3966249A4 (https=)
JP (2) JP2022532556A (https=)
KR (1) KR20220031549A (https=)
CN (1) CN114502586B (https=)
AU (1) AU2020267639A1 (https=)
BR (1) BR112021022365A2 (https=)
CA (1) CA3148027A1 (https=)
IL (1) IL287769A (https=)
MA (1) MA55905A (https=)
MX (1) MX2021013590A (https=)
SG (1) SG11202111927QA (https=)
WO (1) WO2020227475A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020123938A1 (en) 2018-12-14 2020-06-18 Bluebird Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
KR20220004751A (ko) * 2019-05-04 2022-01-11 인히브릭스, 인크. CLEC12a 결합 폴리펩타이드 및 이의 용도
US12421315B2 (en) 2019-05-08 2025-09-23 Regeneron Pharmaceuticals, Inc. CLL-1 targeted immunotherapies
CN119546328A (zh) * 2022-04-08 2025-02-28 再生元制药公司 多部分受体和信号传导复合物
US20250382636A1 (en) 2022-05-26 2025-12-18 Regeneron Pharmaceuticals, Inc. Compositions for maintaining lentiviral vector and uses thereof
CN115772222B (zh) * 2022-12-16 2024-03-29 浙江康佰裕生物科技有限公司 抗cll1单域抗体及其应用
KR102908421B1 (ko) 2025-04-16 2026-01-12 (주)주인정보시스템 인공지능 기반 빌딩 자동제어 시스템 및 그 방법

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6291158B1 (en) 1989-05-16 2001-09-18 Scripps Research Institute Method for tapping the immunological repertoire
US6291161B1 (en) 1989-05-16 2001-09-18 Scripps Research Institute Method for tapping the immunological repertiore
HU215180B (hu) 1992-01-23 1998-10-28 Merck Patent Gmbh. Eljárás monomer és dimer antitest-fragment fúziós fehérjék előállítására
CZ206195A3 (en) 1993-02-12 1996-04-17 Univ Leland Stanford Junior Controlled transcription of target genes and other biological materials
US6972193B1 (en) 1993-02-12 2005-12-06 Board Of Trustees Of Leland Stanford Junior University Regulated transcription of targeted genes and other biological events
ES2229236T3 (es) 1994-01-11 2005-04-16 Dyax Corporation Inhibidores de la plasmina humana derivados de los dominios de kunitz.
US6187757B1 (en) 1995-06-07 2001-02-13 Ariad Pharmaceuticals, Inc. Regulation of biological events using novel compounds
CA2318402A1 (en) 1998-01-15 1999-07-22 Ariad Gene Therapeutics, Inc. Regulation of biological events using multimeric chimeric proteins
AU766513B2 (en) 1998-02-13 2003-10-16 Board Of Trustees Of The Leland Stanford Junior University Novel dimerizing agents, their production and use
AUPP221098A0 (en) 1998-03-06 1998-04-02 Diatech Pty Ltd V-like domain binding molecules
CN103555733A (zh) 2005-01-05 2014-02-05 F-星生物技术研究与开发有限公司 分子中互补决定区以外的区域中工程改造了的具有结合特性的合成免疫球蛋白结构域
GB0504767D0 (en) 2005-03-08 2005-04-13 Ares Trading Sa Lipocalin protein
EP1829895A1 (en) 2006-03-03 2007-09-05 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Bispecific molecule binding TLR9 and CD32 and comprising a T cell epitope for treatment of allergies
WO2010062966A2 (en) 2008-11-26 2010-06-03 The General Hospital Corporation Methods for inducing mixed chimerism
WO2011146862A1 (en) 2010-05-21 2011-11-24 Bellicum Pharmaceuticals, Inc. Methods for inducing selective apoptosis
ES2791716T3 (es) 2010-12-14 2020-11-05 Univ Maryland Células T que expresan al receptor de antígeno quimérico antietiqueta universal y métodos para el tratamiento del cáncer
EP3470431A1 (en) 2012-09-27 2019-04-17 Merus N.V. Bispecific igg antibodies as t cell engagers
EP4303232A3 (en) 2013-02-15 2024-04-17 The Regents of The University of California Chimeric antigen receptor and methods of use thereof
EP2964253A1 (en) 2013-03-05 2016-01-13 Baylor College Of Medicine Heparanase expression in human t lymphocytes
WO2015017214A1 (en) 2013-07-29 2015-02-05 Bluebird Bio, Inc. Multipartite signaling proteins and uses thereof
US10287354B2 (en) * 2013-12-20 2019-05-14 Novartis Ag Regulatable chimeric antigen receptor
US20170081411A1 (en) * 2014-03-15 2017-03-23 Novartis Ag Regulatable chimeric antigen receptor
GB201405845D0 (en) 2014-04-01 2014-05-14 Ucl Business Plc Signalling system
US11542488B2 (en) 2014-07-21 2023-01-03 Novartis Ag Sortase synthesized chimeric antigen receptors
KR20170037625A (ko) 2014-07-21 2017-04-04 노파르티스 아게 Cll-1 키메라 항원 수용체를 사용한 암의 치료
EP3288974B1 (en) 2015-05-01 2020-11-04 Inhibrx, Inc. Type iii secretion system targeting molecules
EP3331913A1 (en) 2015-08-07 2018-06-13 Novartis AG Treatment of cancer using chimeric cd3 receptor proteins
EP3341410B1 (en) 2015-08-24 2021-06-02 Cellectis Chimeric antigen receptors with integrated controllable functions
WO2017125897A1 (en) 2016-01-21 2017-07-27 Novartis Ag Multispecific molecules targeting cll-1
WO2017180993A1 (en) 2016-04-14 2017-10-19 Bluebird Bio, Inc. Salvage chimeric antigen receptor systems
AU2018385699B2 (en) 2017-12-14 2024-08-15 Regeneron Pharmaceuticals, Inc. Daric interleukin receptors
JP7060084B2 (ja) 2018-03-26 2022-04-26 三菱マテリアル株式会社 絶縁回路基板用接合体の製造方法および絶縁回路基板用接合体
US12097219B2 (en) 2018-09-10 2024-09-24 Legend Biotech Ireland Limited Single-domain antibodies against CLL1 and constructs thereof
CA3121478A1 (en) 2018-11-30 2020-06-04 Aleta Biotherapeutics Inc. Single domain antibodies against cll-1
AU2019397152A1 (en) 2018-12-14 2021-06-24 2Seventy Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
WO2020123938A1 (en) 2018-12-14 2020-06-18 Bluebird Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
US20240034768A1 (en) 2018-12-14 2024-02-01 2Seventy Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
US12291560B2 (en) 2018-12-14 2025-05-06 Regeneron Pharmaceuticals, Inc. Dimerizing agent regulated immunoreceptor complexes
KR20220004751A (ko) 2019-05-04 2022-01-11 인히브릭스, 인크. CLEC12a 결합 폴리펩타이드 및 이의 용도
CA3139512A1 (en) 2019-05-08 2020-11-12 Inhibrx, Inc. Cd123 targeted immunotherapies
US12421315B2 (en) 2019-05-08 2025-09-23 Regeneron Pharmaceuticals, Inc. CLL-1 targeted immunotherapies
AU2020359530A1 (en) 2019-09-30 2022-05-19 2Seventy Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
WO2021207613A1 (en) 2020-04-10 2021-10-14 2Seventy Bio, Inc. Frb antibodies
CA3225252A1 (en) 2021-07-14 2023-01-19 Jordan JARJOUR Engineered t cell receptors fused to binding domains from antibodies

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