CN114502586B - Cll-1靶向免疫疗法 - Google Patents

Cll-1靶向免疫疗法 Download PDF

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Publication number
CN114502586B
CN114502586B CN202080049880.5A CN202080049880A CN114502586B CN 114502586 B CN114502586 B CN 114502586B CN 202080049880 A CN202080049880 A CN 202080049880A CN 114502586 B CN114502586 B CN 114502586B
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CN114502586A (zh
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乔丹·贾儒尔
马克·波格森
梁炜亨
卢卡斯·拉斯康
安吉莉卡·萨纳布里亚
约翰·C·蒂默
布伦丹·P·埃克尔曼
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Yinxi Bi Biological Science Co
Regeneron Pharmaceuticals Inc
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Yinxi Bi Biological Science Co
Regeneron Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N9/10—Transferases (2.)
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    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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CN202080049880.5A 2019-05-08 2020-05-07 Cll-1靶向免疫疗法 Active CN114502586B (zh)

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US201962845306P 2019-05-08 2019-05-08
US62/845,306 2019-05-08
PCT/US2020/031781 WO2020227475A1 (en) 2019-05-08 2020-05-07 Cll-1 targeted immunotherapies

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CN114502586B true CN114502586B (zh) 2025-06-24

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EP (1) EP3966249A4 (https=)
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CN (1) CN114502586B (https=)
AU (1) AU2020267639A1 (https=)
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CA (1) CA3148027A1 (https=)
IL (1) IL287769A (https=)
MA (1) MA55905A (https=)
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CN114502586A (zh) 2022-05-13
JP2022532556A (ja) 2022-07-15
KR20220031549A (ko) 2022-03-11
EP3966249A1 (en) 2022-03-16
MA55905A (fr) 2022-03-16
SG11202111927QA (en) 2021-11-29
EP3966249A4 (en) 2023-05-10
CA3148027A1 (en) 2020-11-12
US20260055192A1 (en) 2026-02-26
WO2020227475A1 (en) 2020-11-12
IL287769A (en) 2022-01-01
JP2025081414A (ja) 2025-05-27
BR112021022365A2 (pt) 2022-01-18

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