JP2022532556A5 - - Google Patents

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Publication number
JP2022532556A5
JP2022532556A5 JP2021566149A JP2021566149A JP2022532556A5 JP 2022532556 A5 JP2022532556 A5 JP 2022532556A5 JP 2021566149 A JP2021566149 A JP 2021566149A JP 2021566149 A JP2021566149 A JP 2021566149A JP 2022532556 A5 JP2022532556 A5 JP 2022532556A5
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JP
Japan
Prior art keywords
cell
domain
polypeptide
item
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021566149A
Other languages
English (en)
Japanese (ja)
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JP2022532556A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/031781 external-priority patent/WO2020227475A1/en
Publication of JP2022532556A publication Critical patent/JP2022532556A/ja
Publication of JP2022532556A5 publication Critical patent/JP2022532556A5/ja
Priority to JP2025020891A priority Critical patent/JP2025081414A/ja
Pending legal-status Critical Current

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JP2021566149A 2019-05-08 2020-05-07 Cll-1標的免疫療法 Pending JP2022532556A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025020891A JP2025081414A (ja) 2019-05-08 2025-02-12 Cll-1標的免疫療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962845306P 2019-05-08 2019-05-08
US62/845,306 2019-05-08
PCT/US2020/031781 WO2020227475A1 (en) 2019-05-08 2020-05-07 Cll-1 targeted immunotherapies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025020891A Division JP2025081414A (ja) 2019-05-08 2025-02-12 Cll-1標的免疫療法

Publications (2)

Publication Number Publication Date
JP2022532556A JP2022532556A (ja) 2022-07-15
JP2022532556A5 true JP2022532556A5 (https=) 2023-05-15

Family

ID=73051177

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021566149A Pending JP2022532556A (ja) 2019-05-08 2020-05-07 Cll-1標的免疫療法
JP2025020891A Pending JP2025081414A (ja) 2019-05-08 2025-02-12 Cll-1標的免疫療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025020891A Pending JP2025081414A (ja) 2019-05-08 2025-02-12 Cll-1標的免疫療法

Country Status (13)

Country Link
US (2) US12421315B2 (https=)
EP (1) EP3966249A4 (https=)
JP (2) JP2022532556A (https=)
KR (1) KR20220031549A (https=)
CN (1) CN114502586B (https=)
AU (1) AU2020267639A1 (https=)
BR (1) BR112021022365A2 (https=)
CA (1) CA3148027A1 (https=)
IL (1) IL287769A (https=)
MA (1) MA55905A (https=)
MX (1) MX2021013590A (https=)
SG (1) SG11202111927QA (https=)
WO (1) WO2020227475A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210104772A (ko) 2018-12-14 2021-08-25 블루버드 바이오, 인코포레이티드. 이량체화제로 조절된 면역수용체 복합체
BR112021020999A2 (pt) * 2019-05-04 2021-12-14 Inhibrx Inc Polipeptídeos de ligação à clec12a e usos dos mesmos
KR20220031549A (ko) 2019-05-08 2022-03-11 2세븐티 바이오, 인코포레이티드 Cll-1 표적화 면역요법
CA3255500A1 (en) * 2022-04-08 2023-10-12 Regeneron Pharmaceuticals, Inc. MULTI-PART RECEIVERS AND SIGNALING COMPLEXES
JP2025520227A (ja) 2022-05-26 2025-07-02 リジェネロン・ファーマシューティカルズ・インコーポレイテッド レンチウイルスベクターを維持するための組成物及びその使用
CN115772222B (zh) * 2022-12-16 2024-03-29 浙江康佰裕生物科技有限公司 抗cll1单域抗体及其应用
KR102908421B1 (ko) 2025-04-16 2026-01-12 (주)주인정보시스템 인공지능 기반 빌딩 자동제어 시스템 및 그 방법

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6291161B1 (en) 1989-05-16 2001-09-18 Scripps Research Institute Method for tapping the immunological repertiore
US6291158B1 (en) 1989-05-16 2001-09-18 Scripps Research Institute Method for tapping the immunological repertoire
DE69309472T2 (de) 1992-01-23 1997-10-23 Merck Patent Gmbh, 64293 Darmstadt Fusionsproteine von monomeren und dimeren von antikörperfragmenten
US6972193B1 (en) 1993-02-12 2005-12-06 Board Of Trustees Of Leland Stanford Junior University Regulated transcription of targeted genes and other biological events
EP0804561B1 (en) 1993-02-12 2009-12-30 The Board Of Trustees Of The Leland Stanford Junior University Regulated transcription of targeted genes and other biological events
ATE277081T1 (de) 1994-01-11 2004-10-15 Dyax Corp Inhibitoren des humanplasmins, die sich von den kunitz domänen ableiten
US6187757B1 (en) 1995-06-07 2001-02-13 Ariad Pharmaceuticals, Inc. Regulation of biological events using novel compounds
JP2002508971A (ja) 1998-01-15 2002-03-26 アリアド・ジーン・セラピューティクス・インコーポレーテッド 多量体キメラ蛋白質を使用する生物学的イベントの調節
JP2002503667A (ja) 1998-02-13 2002-02-05 プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ 新規な二量体化剤、その製造および使用
AUPP221098A0 (en) 1998-03-06 1998-04-02 Diatech Pty Ltd V-like domain binding molecules
EP1699826B1 (en) 2005-01-05 2009-03-11 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
GB0504767D0 (en) 2005-03-08 2005-04-13 Ares Trading Sa Lipocalin protein
EP1829895A1 (en) 2006-03-03 2007-09-05 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Bispecific molecule binding TLR9 and CD32 and comprising a T cell epitope for treatment of allergies
WO2010062966A2 (en) 2008-11-26 2010-06-03 The General Hospital Corporation Methods for inducing mixed chimerism
US9089520B2 (en) 2010-05-21 2015-07-28 Baylor College Of Medicine Methods for inducing selective apoptosis
US9233125B2 (en) 2010-12-14 2016-01-12 University Of Maryland, Baltimore Universal anti-tag chimeric antigen receptor-expressing T cells and methods of treating cancer
HUE042040T2 (hu) 2012-09-27 2019-06-28 Merus Nv Bispecifikus IGG antitestek mint T-sejt kapcsolók
DK2956175T3 (da) 2013-02-15 2017-11-27 Univ California Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf
CA2904236A1 (en) 2013-03-05 2014-09-12 Baylor College Of Medicine Heparanase expression in t lymphocytes
EP3925618A1 (en) 2013-07-29 2021-12-22 2seventy bio, Inc. Multipartite signaling proteins and uses thereof
EP3087101B1 (en) * 2013-12-20 2024-06-05 Novartis AG Regulatable chimeric antigen receptor
ES2857226T3 (es) * 2014-03-15 2021-09-28 Novartis Ag Receptor de antígeno quimérico regulable
GB201405845D0 (en) 2014-04-01 2014-05-14 Ucl Business Plc Signalling system
SG10201913782UA (en) * 2014-07-21 2020-03-30 Novartis Ag Treatment of cancer using a cll-1 chimeric antigen receptor
US11542488B2 (en) 2014-07-21 2023-01-03 Novartis Ag Sortase synthesized chimeric antigen receptors
ES2846881T3 (es) * 2015-05-01 2021-07-30 Inhibrx Inc Moléculas que se dirigen al sistema de secreción de tipo III
US11667691B2 (en) 2015-08-07 2023-06-06 Novartis Ag Treatment of cancer using chimeric CD3 receptor proteins
EP3341410B1 (en) * 2015-08-24 2021-06-02 Cellectis Chimeric antigen receptors with integrated controllable functions
MA55746A (fr) 2016-01-21 2022-03-02 Novartis Ag Molécules multispécifiques ciblant cll-1
EP3443002A4 (en) 2016-04-14 2019-12-04 Bluebird Bio, Inc. SYSTEMS FOR RECOVERED CHIMERIC ANTIGEN RECEPTORS
CA3084551A1 (en) 2017-12-14 2019-06-20 Bluebird Bio, Inc. Daric interleukin receptors
CN111819682B (zh) 2018-03-26 2025-04-29 三菱综合材料株式会社 绝缘电路基板用接合体的制造方法及绝缘电路基板用接合体
EP3850013A4 (en) 2018-09-10 2022-10-05 Nanjing Legend Biotech Co., Ltd. SINGLE DOMAIN ANTIBODIES AGAINST CLL1 AND USES THEREOF
WO2020113063A1 (en) 2018-11-30 2020-06-04 Aleta Biotherapeutics Inc. Single domain antibodies against cll-1
US20240025963A1 (en) 2018-12-14 2024-01-25 2Seventy Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
KR20210104772A (ko) 2018-12-14 2021-08-25 블루버드 바이오, 인코포레이티드. 이량체화제로 조절된 면역수용체 복합체
US20240034768A1 (en) 2018-12-14 2024-02-01 2Seventy Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
WO2020123947A1 (en) 2018-12-14 2020-06-18 Bluebird Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
BR112021020999A2 (pt) 2019-05-04 2021-12-14 Inhibrx Inc Polipeptídeos de ligação à clec12a e usos dos mesmos
MA55910A (fr) 2019-05-08 2022-03-16 2Seventy Bio Inc Immunothérapies ciblant cd123
KR20220031549A (ko) 2019-05-08 2022-03-11 2세븐티 바이오, 인코포레이티드 Cll-1 표적화 면역요법
AU2020359530A1 (en) 2019-09-30 2022-05-19 2Seventy Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
US12454580B2 (en) 2020-04-10 2025-10-28 Regeneron Pharmaceuticals, Inc. FRB antibodies
JP2024525727A (ja) 2021-07-14 2024-07-12 2セブンティ バイオ インコーポレイテッド 抗体由来の結合ドメインに融合した操作されたt細胞受容体

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