JPWO2020210655A5 - - Google Patents
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- Publication number
- JPWO2020210655A5 JPWO2020210655A5 JP2021559829A JP2021559829A JPWO2020210655A5 JP WO2020210655 A5 JPWO2020210655 A5 JP WO2020210655A5 JP 2021559829 A JP2021559829 A JP 2021559829A JP 2021559829 A JP2021559829 A JP 2021559829A JP WO2020210655 A5 JPWO2020210655 A5 JP WO2020210655A5
- Authority
- JP
- Japan
- Prior art keywords
- aav capsid
- amino acid
- aav
- acid sequence
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962832826P | 2019-04-11 | 2019-04-11 | |
| US62/832,826 | 2019-04-11 | ||
| PCT/US2020/027708 WO2020210655A1 (en) | 2019-04-11 | 2020-04-10 | Virus compositions with enhanced specificity in the brain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022526018A JP2022526018A (ja) | 2022-05-20 |
| JPWO2020210655A5 true JPWO2020210655A5 (uk) | 2023-03-31 |
Family
ID=72751358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021559829A Pending JP2022526018A (ja) | 2019-04-11 | 2020-04-10 | 脳内への特異性が増強されたウイルス組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220220502A1 (uk) |
| EP (1) | EP3953371A4 (uk) |
| JP (1) | JP2022526018A (uk) |
| KR (1) | KR20220007056A (uk) |
| CN (1) | CN114127090A (uk) |
| AU (1) | AU2020271108A1 (uk) |
| CA (1) | CA3136658A1 (uk) |
| SG (1) | SG11202111249YA (uk) |
| WO (1) | WO2020210655A1 (uk) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112703198A (zh) | 2018-07-11 | 2021-04-23 | 布里格姆妇女医院 | 用于跨血脑屏障递送试剂的方法和组合物 |
| KR20210084459A (ko) | 2018-09-26 | 2021-07-07 | 캘리포니아 인스티튜트 오브 테크놀로지 | 표적화된 유전자 요법을 위한 아데노-연관 바이러스 조성물 |
| WO2021141692A2 (en) | 2019-11-22 | 2021-07-15 | California Institute Of Technology | Method for robust control of gene expression |
| US11981705B2 (en) | 2020-01-10 | 2024-05-14 | The Brigham And Women's Hospital, Inc. | Methods and compositions for delivery of immunotherapy agents across the blood-brain barrier to treat brain cancer |
| TW202208397A (zh) | 2020-05-13 | 2022-03-01 | 美商航海家醫療公司 | Aav蛋白殼之趨性重定向 |
| US20240100187A1 (en) * | 2020-12-18 | 2024-03-28 | Ac Immune Sa | Antibody Delivery |
| WO2022221421A2 (en) * | 2021-04-13 | 2022-10-20 | Capsida, Inc. | Aav compositions with high brain expression for treating mucopolysaccharidosis ii |
| EP4323013A2 (en) * | 2021-04-13 | 2024-02-21 | Capsida, Inc. | Selected aav compositions having preferred brain enrichment |
| WO2022221400A2 (en) * | 2021-04-13 | 2022-10-20 | Capsida, Inc. | Aav compositions having high expression levels in brain |
| US20240325568A1 (en) * | 2021-07-20 | 2024-10-03 | The Broad Institute, Inc. | Engineered targeting compositions for endothelial cells of the central nervous system vasculature and methods of use thereof |
| WO2023060264A1 (en) | 2021-10-08 | 2023-04-13 | Dyno Therapeutics, Inc. | Capsid variants and methods of using the same |
| EP4432836A1 (en) * | 2021-11-16 | 2024-09-25 | California Institute of Technology | Adeno-associated virus compositions having preferred heart and skeletal muscle enrichment |
| WO2023148617A1 (en) * | 2022-02-01 | 2023-08-10 | The Broad Institute, Inc. | Adeno-associated viral vectors and uses thereof |
| WO2023150632A2 (en) * | 2022-02-02 | 2023-08-10 | The Broad Institute, Inc. | Targeting moieties promoting transduction of central nervous system cells and tissues and methods of use |
| WO2023235791A1 (en) * | 2022-06-02 | 2023-12-07 | Voyager Therapeutics, Inc. | Aav capsid variants and uses thereof |
| KR20240014846A (ko) * | 2022-07-26 | 2024-02-02 | 숙명여자대학교산학협력단 | Aav2-anks1a 재조합 바이러스를 포함하는 알츠하이머 질병 치료용 조성물 |
| WO2024086747A1 (en) | 2022-10-19 | 2024-04-25 | Affinia Therapeutics Inc. | Recombinant aavs with improved tropism and specificity |
| CN116693633B (zh) * | 2023-02-21 | 2023-12-22 | 广州派真生物技术有限公司 | 腺相关病毒突变体及其应用 |
| WO2024191778A1 (en) | 2023-03-10 | 2024-09-19 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3738974A1 (en) * | 2012-09-28 | 2020-11-18 | The University of North Carolina at Chapel Hill | Aav vectors targeted to oligodendrocytes |
| WO2015038958A1 (en) * | 2013-09-13 | 2015-03-19 | California Institute Of Technology | Selective recovery |
| KR102423442B1 (ko) * | 2015-12-11 | 2022-07-20 | 캘리포니아 인스티튜트 오브 테크놀로지 | 아데노-관련 바이러스를 지시하기 위한 타겟팅 펩타이드 |
| WO2019046069A1 (en) * | 2017-08-28 | 2019-03-07 | The Regents Of The University Of California | ADENO-ASSOCIATED VIRUS CAPSID VARIANTS AND METHODS OF USE |
-
2020
- 2020-04-10 EP EP20787580.8A patent/EP3953371A4/en active Pending
- 2020-04-10 CN CN202080043549.2A patent/CN114127090A/zh active Pending
- 2020-04-10 CA CA3136658A patent/CA3136658A1/en active Pending
- 2020-04-10 US US17/602,505 patent/US20220220502A1/en active Pending
- 2020-04-10 AU AU2020271108A patent/AU2020271108A1/en active Pending
- 2020-04-10 KR KR1020217036564A patent/KR20220007056A/ko unknown
- 2020-04-10 SG SG11202111249YA patent/SG11202111249YA/en unknown
- 2020-04-10 WO PCT/US2020/027708 patent/WO2020210655A1/en unknown
- 2020-04-10 JP JP2021559829A patent/JP2022526018A/ja active Pending
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