JPWO2020185121A5 - - Google Patents

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Publication number
JPWO2020185121A5
JPWO2020185121A5 JP2021555415A JP2021555415A JPWO2020185121A5 JP WO2020185121 A5 JPWO2020185121 A5 JP WO2020185121A5 JP 2021555415 A JP2021555415 A JP 2021555415A JP 2021555415 A JP2021555415 A JP 2021555415A JP WO2020185121 A5 JPWO2020185121 A5 JP WO2020185121A5
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JP
Japan
Prior art keywords
amino acid
acid sequence
seq
car
chimeric antigen
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JP2021555415A
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English (en)
Japanese (ja)
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JP7735186B2 (ja
JP2022526720A5 (https=
JP2022526720A (ja
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Priority claimed from RU2019107136A external-priority patent/RU2742000C2/ru
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Publication of JPWO2020185121A5 publication Critical patent/JPWO2020185121A5/ja
Publication of JP2022526720A5 publication Critical patent/JP2022526720A5/ja
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JP2021555415A 2019-03-13 2020-03-13 キメラ抗原受容体の代替の細胞内シグナル伝達ドメイン Active JP7735186B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2019107136A RU2742000C2 (ru) 2019-03-13 2019-03-13 Выделенный альтернативный внутриклеточный сигнальный домен химерного антигенного рецептора и включающий его химерный антигенный рецептор
RU2019107136 2019-03-13
PCT/RU2020/000136 WO2020185121A2 (ru) 2019-03-13 2020-03-13 Выделенный альтернативный внутриклеточный сигнальный домен химерного антигенного рецептора и включающий его химерный антигенный рецептор

Publications (4)

Publication Number Publication Date
JP2022526720A JP2022526720A (ja) 2022-05-26
JPWO2020185121A5 true JPWO2020185121A5 (https=) 2023-03-17
JP2022526720A5 JP2022526720A5 (https=) 2023-03-17
JP7735186B2 JP7735186B2 (ja) 2025-09-08

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ID=72425914

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JP2021555415A Active JP7735186B2 (ja) 2019-03-13 2020-03-13 キメラ抗原受容体の代替の細胞内シグナル伝達ドメイン

Country Status (7)

Country Link
US (1) US12540169B2 (https=)
EP (1) EP3974444A4 (https=)
JP (1) JP7735186B2 (https=)
KR (1) KR20220157861A (https=)
CN (1) CN114206918A (https=)
RU (1) RU2742000C2 (https=)
WO (1) WO2020185121A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201713078D0 (en) * 2017-08-15 2017-09-27 Adaptimmune Ltd T Cell Modification
AU2020232691B2 (en) 2019-03-05 2023-06-29 Nkarta, Inc. CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
WO2022081486A1 (en) * 2020-10-12 2022-04-21 Sorrento Therapeutics, Inc. Cd19-directed chimeric antigen receptor constructs

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5585362A (en) 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
US5350674A (en) 1992-09-04 1994-09-27 Becton, Dickinson And Company Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
CA2386270A1 (en) 1999-10-15 2001-04-26 University Of Massachusetts Rna interference pathway genes as tools for targeted genetic interference
US6326193B1 (en) 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
AU2001275474A1 (en) 2000-06-12 2001-12-24 Akkadix Corporation Materials and methods for the control of nematodes
US20130266551A1 (en) * 2003-11-05 2013-10-10 St. Jude Children's Research Hospital, Inc. Chimeric receptors with 4-1bb stimulatory signaling domain
WO2014153114A1 (en) * 2013-03-14 2014-09-25 Fred Hutchinson Cancer Research Center Compositions and methods to modify cells for therapeutic objectives
PL3546572T3 (pl) * 2013-05-13 2024-07-22 Cellectis Chimeryczny receptor antygenowy swoisty względem cd19 i jego zastosowania
WO2015069922A2 (en) * 2013-11-06 2015-05-14 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Alk antibodies, conjugates, and chimeric antigen receptors, and their use
MX383150B (es) * 2014-06-02 2025-03-13 Us Health Receptores quiméricos de antígeno que tienen como diana a cd-19.
EP3393504B1 (en) * 2015-12-22 2025-09-24 Novartis AG Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
WO2018132506A1 (en) 2017-01-10 2018-07-19 The General Hospital Corporation Chimeric antigen receptors based on alternative signal 1 domains

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