KR20220157861A - 키메라 항원 수용체의 얼터너티브 세포내 신호전달 도메인 - Google Patents

키메라 항원 수용체의 얼터너티브 세포내 신호전달 도메인 Download PDF

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KR20220157861A
KR20220157861A KR1020217032967A KR20217032967A KR20220157861A KR 20220157861 A KR20220157861 A KR 20220157861A KR 1020217032967 A KR1020217032967 A KR 1020217032967A KR 20217032967 A KR20217032967 A KR 20217032967A KR 20220157861 A KR20220157861 A KR 20220157861A
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gly
car
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파벨 미하일로비치 게르쇼비치
알렉산드르 블라디미로비치 카라벨스키
안드레이 보리소비치 우리틴
드미트리 알렉산드로비치 마데라
로만 알렉세예비치 이바노프
드미트리 발렌티노비치 모로조프
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리미티드 라이어빌리티 컴퍼니 “아나비온”
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KR1020217032967A 2019-03-13 2020-03-13 키메라 항원 수용체의 얼터너티브 세포내 신호전달 도메인 Ceased KR20220157861A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2019107136A RU2742000C2 (ru) 2019-03-13 2019-03-13 Выделенный альтернативный внутриклеточный сигнальный домен химерного антигенного рецептора и включающий его химерный антигенный рецептор
RU2019107136 2019-03-13
PCT/RU2020/000136 WO2020185121A2 (ru) 2019-03-13 2020-03-13 Выделенный альтернативный внутриклеточный сигнальный домен химерного антигенного рецептора и включающий его химерный антигенный рецептор

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KR20220157861A true KR20220157861A (ko) 2022-11-29

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US (1) US12540169B2 (https=)
EP (1) EP3974444A4 (https=)
JP (1) JP7735186B2 (https=)
KR (1) KR20220157861A (https=)
CN (1) CN114206918A (https=)
RU (1) RU2742000C2 (https=)
WO (1) WO2020185121A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201713078D0 (en) * 2017-08-15 2017-09-27 Adaptimmune Ltd T Cell Modification
AU2020232691B2 (en) 2019-03-05 2023-06-29 Nkarta, Inc. CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
WO2022081486A1 (en) * 2020-10-12 2022-04-21 Sorrento Therapeutics, Inc. Cd19-directed chimeric antigen receptor constructs

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5585362A (en) 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
US5350674A (en) 1992-09-04 1994-09-27 Becton, Dickinson And Company Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
CA2386270A1 (en) 1999-10-15 2001-04-26 University Of Massachusetts Rna interference pathway genes as tools for targeted genetic interference
US6326193B1 (en) 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
AU2001275474A1 (en) 2000-06-12 2001-12-24 Akkadix Corporation Materials and methods for the control of nematodes
US20130266551A1 (en) * 2003-11-05 2013-10-10 St. Jude Children's Research Hospital, Inc. Chimeric receptors with 4-1bb stimulatory signaling domain
WO2014153114A1 (en) * 2013-03-14 2014-09-25 Fred Hutchinson Cancer Research Center Compositions and methods to modify cells for therapeutic objectives
PL3546572T3 (pl) * 2013-05-13 2024-07-22 Cellectis Chimeryczny receptor antygenowy swoisty względem cd19 i jego zastosowania
WO2015069922A2 (en) * 2013-11-06 2015-05-14 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Alk antibodies, conjugates, and chimeric antigen receptors, and their use
MX383150B (es) * 2014-06-02 2025-03-13 Us Health Receptores quiméricos de antígeno que tienen como diana a cd-19.
EP3393504B1 (en) * 2015-12-22 2025-09-24 Novartis AG Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
WO2018132506A1 (en) 2017-01-10 2018-07-19 The General Hospital Corporation Chimeric antigen receptors based on alternative signal 1 domains

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Publication number Publication date
JP7735186B2 (ja) 2025-09-08
CN114206918A (zh) 2022-03-18
WO2020185121A3 (ru) 2020-11-05
WO2020185121A2 (ru) 2020-09-17
EP3974444A2 (en) 2022-03-30
RU2019107136A (ru) 2020-09-14
JP2022526720A (ja) 2022-05-26
US20220127329A1 (en) 2022-04-28
EP3974444A4 (en) 2023-04-19
RU2019107136A3 (https=) 2020-09-14
US12540169B2 (en) 2026-02-03
RU2742000C2 (ru) 2021-02-01

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