JPWO2020176654A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020176654A5 JPWO2020176654A5 JP2021550133A JP2021550133A JPWO2020176654A5 JP WO2020176654 A5 JPWO2020176654 A5 JP WO2020176654A5 JP 2021550133 A JP2021550133 A JP 2021550133A JP 2021550133 A JP2021550133 A JP 2021550133A JP WO2020176654 A5 JPWO2020176654 A5 JP WO2020176654A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- independently selected
- compound
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962811432P | 2019-02-27 | 2019-02-27 | |
| US62/811,432 | 2019-02-27 | ||
| US201962819204P | 2019-03-15 | 2019-03-15 | |
| US62/819,204 | 2019-03-15 | ||
| US201962825667P | 2019-03-28 | 2019-03-28 | |
| US62/825,667 | 2019-03-28 | ||
| US201962840254P | 2019-04-29 | 2019-04-29 | |
| US62/840,254 | 2019-04-29 | ||
| US201962871694P | 2019-07-08 | 2019-07-08 | |
| US62/871,694 | 2019-07-08 | ||
| US201962885055P | 2019-08-09 | 2019-08-09 | |
| US62/885,055 | 2019-08-09 | ||
| US201962901142P | 2019-09-16 | 2019-09-16 | |
| US62/901,142 | 2019-09-16 | ||
| US201962931043P | 2019-11-05 | 2019-11-05 | |
| US62/931,043 | 2019-11-05 | ||
| US202062975088P | 2020-02-11 | 2020-02-11 | |
| US62/975,088 | 2020-02-11 | ||
| PCT/US2020/019944 WO2020176654A1 (en) | 2019-02-27 | 2020-02-26 | Use of caseinolytic protease p function as a biomarker of drug response to imipridone-like agents |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022521797A JP2022521797A (ja) | 2022-04-12 |
| JPWO2020176654A5 true JPWO2020176654A5 (https=) | 2023-02-17 |
| JP2022521797A5 JP2022521797A5 (https=) | 2023-02-17 |
| JP7709379B2 JP7709379B2 (ja) | 2025-07-16 |
Family
ID=72238693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021550133A Active JP7709379B2 (ja) | 2019-02-27 | 2020-02-26 | イミプリドン様薬剤に対する薬物反応のバイオマーカとしてのカゼイン分解プロテアーゼｐの機能の使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12459945B2 (https=) |
| EP (1) | EP3930714A4 (https=) |
| JP (1) | JP7709379B2 (https=) |
| CN (2) | CN113795251B (https=) |
| AU (2) | AU2020228047B2 (https=) |
| CA (1) | CA3131740A1 (https=) |
| WO (1) | WO2020176654A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230339947A1 (en) * | 2019-02-27 | 2023-10-26 | Madera Therapeutics, LLC | Use of caseinolytic protease p function as a biomarker of drug response to imipridone-like agents |
| EP4337214A4 (en) * | 2021-05-13 | 2025-01-29 | Chimerix, Inc. | USES AND METHODS FOR RECURRENT PRIMARY CNS NEOPLASMAS |
| CN115611896A (zh) * | 2021-07-16 | 2023-01-17 | 中国药科大学 | 含四氢萘啶酮或四氢吡啶并嘧啶酮骨架的化合物及其制备方法与制药用途 |
| WO2024030645A1 (en) * | 2022-08-05 | 2024-02-08 | Chimerix, Inc. | Pharmaceutical compositions and uses thereof for the treatment of glioma |
| WO2024199457A1 (zh) * | 2023-03-31 | 2024-10-03 | 苏州安赛隆医药科技有限公司 | 并环结构化合物、其制备方法及其用途以及药物组合物及其用途 |
| CN119039287A (zh) * | 2023-05-29 | 2024-11-29 | 中国药科大学 | 一类四氢吡啶并嘧啶酮衍生物及其制备方法与应用 |
| EP4488279A1 (en) * | 2023-07-03 | 2025-01-08 | Centro Atlantico del Medicamento S.A (Ceamed, S.A) | Substituted hexahydro-2h-pyrazino[1,2-a]pyrazin-1(6h)-one derivatives as activators of human caseinolytic protease p (hsclpp) |
| WO2025011546A1 (en) * | 2023-07-10 | 2025-01-16 | Acelon Therapeutics | Human caseinolytic protease p agonists and uses thereof |
| CN119306718A (zh) * | 2023-07-11 | 2025-01-14 | 中科中山药物创新研究院 | 一种咪唑并吡啶并嘧啶酮类化合物及其制备方法和应用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525464A (en) | 1987-04-01 | 1996-06-11 | Hyseq, Inc. | Method of sequencing by hybridization of oligonucleotide probes |
| US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| GB8810400D0 (en) | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
| US5547839A (en) | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
| US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| EP0430881A3 (en) | 1989-11-29 | 1991-10-23 | Ciba-Geigy Ag | Photochromic compounds, process for their preparation and their use |
| US5288644A (en) | 1990-04-04 | 1994-02-22 | The Rockefeller University | Instrument and method for the sequencing of genome |
| US5324633A (en) | 1991-11-22 | 1994-06-28 | Affymax Technologies N.V. | Method and apparatus for measuring binding affinity |
| ATE173767T1 (de) | 1992-04-03 | 1998-12-15 | Perkin Elmer Corp | Proben zusammensetzung und verfahren |
| US5503980A (en) | 1992-11-06 | 1996-04-02 | Trustees Of Boston University | Positional sequencing by hybridization |
| DE59408453D1 (de) | 1993-04-23 | 1999-08-12 | Hoechst Ag | Pyrido-pyrimidindione, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US5858659A (en) | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
| US5470710A (en) | 1993-10-22 | 1995-11-28 | University Of Utah | Automated hybridization/imaging device for fluorescent multiplex DNA sequencing |
| GB9401833D0 (en) | 1994-02-01 | 1994-03-30 | Isis Innovation | Method for discovering ligands |
| GB9507238D0 (en) | 1995-04-07 | 1995-05-31 | Isis Innovation | Detecting dna sequence variations |
| GB9518953D0 (en) | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
| US5661028A (en) | 1995-09-29 | 1997-08-26 | Lockheed Martin Energy Systems, Inc. | Large scale DNA microsequencing device |
| JP2002515738A (ja) | 1996-01-23 | 2002-05-28 | アフィメトリックス，インコーポレイティド | 核酸分析法 |
| WO2008130584A1 (en) * | 2007-04-20 | 2008-10-30 | Schering Corporation | Pyrimidinone derivatives and methods of use thereof |
| US20110275647A1 (en) * | 2009-02-23 | 2011-11-10 | Msd K.K. | Pyrimidin-4-(3h)-one derivatives |
| WO2012079164A1 (en) | 2010-12-16 | 2012-06-21 | The Governing Council Of The University Of Toronto | Activators of cylindrical proteases |
| LT3662910T (lt) | 2014-03-31 | 2024-12-27 | The Scripps Research Institute | Trail geno indukcijai skirtas farmakoforas |
| CN104860948B (zh) | 2015-05-15 | 2017-09-26 | 南京盖特医药技术有限公司 | 咪唑并嘧啶酮类化合物及其制备方法和应用 |
| AU2017310529B2 (en) | 2016-08-12 | 2021-08-19 | Edwin J. Iwanowicz | Protein kinase regulators |
| WO2018031987A1 (en) | 2016-08-12 | 2018-02-15 | Nanjing Gator Meditech Company, Ltd. | Protein kinase regulators |
| US20220143024A1 (en) | 2019-02-22 | 2022-05-12 | Board Of Regents, The University Of Texas System | Methods of using imipridones |
| US20230339947A1 (en) * | 2019-02-27 | 2023-10-26 | Madera Therapeutics, LLC | Use of caseinolytic protease p function as a biomarker of drug response to imipridone-like agents |
-
2020
- 2020-02-26 AU AU2020228047A patent/AU2020228047B2/en active Active
- 2020-02-26 CN CN202080031455.3A patent/CN113795251B/zh active Active
- 2020-02-26 CA CA3131740A patent/CA3131740A1/en active Pending
- 2020-02-26 EP EP20762147.5A patent/EP3930714A4/en active Pending
- 2020-02-26 CN CN202511975073.7A patent/CN121758447A/zh active Pending
- 2020-02-26 JP JP2021550133A patent/JP7709379B2/ja active Active
- 2020-02-26 WO PCT/US2020/019944 patent/WO2020176654A1/en not_active Ceased
-
2021
- 2021-08-27 US US17/459,960 patent/US12459945B2/en active Active
-
2026
- 2026-02-13 AU AU2026201069A patent/AU2026201069A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2003519676A5 (https=) | ||
| JPWO2020176654A5 (https=) | ||
| JP2005523922A5 (https=) | ||
| AR063804A1 (es) | Compuestos de azoniabiciclo[2.2.2]octano | |
| JPWO2022000091A5 (https=) | ||
| AR067896A1 (es) | Procedimiento para sintetizar compuestos utiles para tratar hepatitis c | |
| JPWO2022216971A5 (https=) | ||
| JP2008504265A5 (https=) | ||
| JPWO2020243415A5 (https=) | ||
| JP2007511504A5 (https=) | ||
| JP2009535358A5 (https=) | ||
| JP2006511587A5 (https=) | ||
| JP2003525286A5 (https=) | ||
| JPWO2021030555A5 (https=) | ||
| JP2021528421A5 (https=) | ||
| JP2005526773A5 (https=) | ||
| JPH1081664A5 (https=) | ||
| KR880011082A (ko) | β-아미노 에틸-치환된 페닐 화합물 및 그들의 약제학적으로 허용되는 염 및 아미드 | |
| JP2021529752A5 (https=) | ||
| JP2021532183A5 (https=) | ||
| JP2006514956A5 (https=) | ||
| JPWO2022261383A5 (https=) | ||
| JP2007532625A5 (https=) | ||
| JP2006517932A5 (https=) | ||
| JPWO2023072240A5 (https=) |