JP2021529752A5 - - Google Patents

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Publication number
JP2021529752A5
JP2021529752A5 JP2020572891A JP2020572891A JP2021529752A5 JP 2021529752 A5 JP2021529752 A5 JP 2021529752A5 JP 2020572891 A JP2020572891 A JP 2020572891A JP 2020572891 A JP2020572891 A JP 2020572891A JP 2021529752 A5 JP2021529752 A5 JP 2021529752A5
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JP
Japan
Prior art keywords
alkyl
alkoxy
group
heteroaryl
aryl
Prior art date
Application number
JP2020572891A
Other languages
English (en)
Japanese (ja)
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JP2021529752A (ja
JP7396682B2 (ja
JPWO2020006557A5 (https=
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Priority claimed from PCT/US2019/040121 external-priority patent/WO2020006557A1/en
Publication of JP2021529752A publication Critical patent/JP2021529752A/ja
Publication of JP2021529752A5 publication Critical patent/JP2021529752A5/ja
Publication of JPWO2020006557A5 publication Critical patent/JPWO2020006557A5/ja
Application granted granted Critical
Publication of JP7396682B2 publication Critical patent/JP7396682B2/ja
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JP2020572891A 2018-06-29 2019-07-01 イタコン酸誘導体の組成物及び使用方法 Active JP7396682B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862763735P 2018-06-29 2018-06-29
US62/763,735 2018-06-29
PCT/US2019/040121 WO2020006557A1 (en) 2018-06-29 2019-07-01 Compositions and methods of using itaconic acid derivatives

Publications (4)

Publication Number Publication Date
JP2021529752A JP2021529752A (ja) 2021-11-04
JP2021529752A5 true JP2021529752A5 (https=) 2022-06-21
JPWO2020006557A5 JPWO2020006557A5 (https=) 2022-06-21
JP7396682B2 JP7396682B2 (ja) 2023-12-12

Family

ID=68985877

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020572891A Active JP7396682B2 (ja) 2018-06-29 2019-07-01 イタコン酸誘導体の組成物及び使用方法

Country Status (5)

Country Link
US (1) US12060310B2 (https=)
EP (1) EP3813815B1 (https=)
JP (1) JP7396682B2 (https=)
ES (1) ES3063485T3 (https=)
WO (1) WO2020006557A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA55795A (fr) 2019-04-30 2022-03-09 Sitryx Therapeutics Ltd Dérivés d'acide itaconique et leurs utilisations dans le traitement d'une maladie inflammatoire ou d'une maladie associée à une réponse immunitaire indésirable
EP4237404A1 (en) * 2020-10-29 2023-09-06 Sitryx Therapeutics Limited Novel compounds
EP4326247A1 (en) 2021-04-23 2024-02-28 Helmholtz-Zentrum für Infektionsforschung GmbH Citraconic acid and derivatives thereof for use as a medicament
CN119685257B (zh) * 2024-12-16 2026-02-27 华中科技大学同济医学院附属协和医院 体外诱导t细胞免疫记忆分化的方法及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260479A (en) * 1991-12-16 1993-11-09 Merck & Co., Inc. Inhibitors of farnesyl protein transferase
EP1062954B1 (en) * 1998-10-27 2007-05-30 Suntory Limited Use of itaconic acid for regulation of glycolytic metabolism
EP2480531B1 (en) * 2009-09-21 2014-11-05 ChemoCentryx, Inc. Pyrrolidinone carboxamide derivatives as chemerin-r (chemr23) modulators
LU91877B1 (en) * 2011-09-23 2013-03-25 Univ Luxembourg Method to predict the presence of itaconic Acid, IRG1 and/or protein IRG1 in a subject and pharmaceutical composition for performing gene therapy
US8691993B2 (en) * 2011-12-12 2014-04-08 Hoffmann-La Roche Inc. Piperidinyl naphthylacetic acids
JP2015516965A (ja) * 2012-04-03 2015-06-18 アポセンス リミテッドＡｐｏｓｅｎｓｅ Ｌｔｄ． 診断指標及び治療指標のための新規な標的指向性薬剤
EP3416634A4 (en) * 2016-02-15 2019-10-09 Artyomov, Maxim IMMUNOMODULATORY AGENTS AND METHOD FOR USE THEREOF

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