ES3063485T3 - Compositions and methods of using itaconic acid derivatives - Google Patents
Compositions and methods of using itaconic acid derivativesInfo
- Publication number
- ES3063485T3 ES3063485T3 ES19826034T ES19826034T ES3063485T3 ES 3063485 T3 ES3063485 T3 ES 3063485T3 ES 19826034 T ES19826034 T ES 19826034T ES 19826034 T ES19826034 T ES 19826034T ES 3063485 T3 ES3063485 T3 ES 3063485T3
- Authority
- ES
- Spain
- Prior art keywords
- compositions
- methods
- acid derivatives
- itaconic acid
- itaconic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/44—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by unsaturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/42—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862763735P | 2018-06-29 | 2018-06-29 | |
| PCT/US2019/040121 WO2020006557A1 (en) | 2018-06-29 | 2019-07-01 | Compositions and methods of using itaconic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES3063485T3 true ES3063485T3 (en) | 2026-04-16 |
Family
ID=68985877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES19826034T Active ES3063485T3 (en) | 2018-06-29 | 2019-07-01 | Compositions and methods of using itaconic acid derivatives |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12060310B2 (https=) |
| EP (1) | EP3813815B1 (https=) |
| JP (1) | JP7396682B2 (https=) |
| ES (1) | ES3063485T3 (https=) |
| WO (1) | WO2020006557A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA55795A (fr) | 2019-04-30 | 2022-03-09 | Sitryx Therapeutics Ltd | Dérivés d'acide itaconique et leurs utilisations dans le traitement d'une maladie inflammatoire ou d'une maladie associée à une réponse immunitaire indésirable |
| EP4237404A1 (en) * | 2020-10-29 | 2023-09-06 | Sitryx Therapeutics Limited | Novel compounds |
| EP4326247A1 (en) | 2021-04-23 | 2024-02-28 | Helmholtz-Zentrum für Infektionsforschung GmbH | Citraconic acid and derivatives thereof for use as a medicament |
| CN119685257B (zh) * | 2024-12-16 | 2026-02-27 | 华中科技大学同济医学院附属协和医院 | 体外诱导t细胞免疫记忆分化的方法及应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260479A (en) * | 1991-12-16 | 1993-11-09 | Merck & Co., Inc. | Inhibitors of farnesyl protein transferase |
| EP1062954B1 (en) * | 1998-10-27 | 2007-05-30 | Suntory Limited | Use of itaconic acid for regulation of glycolytic metabolism |
| EP2480531B1 (en) * | 2009-09-21 | 2014-11-05 | ChemoCentryx, Inc. | Pyrrolidinone carboxamide derivatives as chemerin-r (chemr23) modulators |
| LU91877B1 (en) * | 2011-09-23 | 2013-03-25 | Univ Luxembourg | Method to predict the presence of itaconic Acid, IRG1 and/or protein IRG1 in a subject and pharmaceutical composition for performing gene therapy |
| US8691993B2 (en) * | 2011-12-12 | 2014-04-08 | Hoffmann-La Roche Inc. | Piperidinyl naphthylacetic acids |
| JP2015516965A (ja) * | 2012-04-03 | 2015-06-18 | アポセンス リミテッドＡｐｏｓｅｎｓｅ Ｌｔｄ． | 診断指標及び治療指標のための新規な標的指向性薬剤 |
| EP3416634A4 (en) * | 2016-02-15 | 2019-10-09 | Artyomov, Maxim | IMMUNOMODULATORY AGENTS AND METHOD FOR USE THEREOF |
-
2019
- 2019-07-01 ES ES19826034T patent/ES3063485T3/es active Active
- 2019-07-01 JP JP2020572891A patent/JP7396682B2/ja active Active
- 2019-07-01 EP EP19826034.1A patent/EP3813815B1/en active Active
- 2019-07-01 US US17/255,150 patent/US12060310B2/en active Active
- 2019-07-01 WO PCT/US2019/040121 patent/WO2020006557A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021529752A (ja) | 2021-11-04 |
| EP3813815A1 (en) | 2021-05-05 |
| JP7396682B2 (ja) | 2023-12-12 |
| EP3813815C0 (en) | 2026-01-28 |
| EP3813815A4 (en) | 2022-04-20 |
| US20210261495A1 (en) | 2021-08-26 |
| EP3813815B1 (en) | 2026-01-28 |
| US12060310B2 (en) | 2024-08-13 |
| WO2020006557A1 (en) | 2020-01-02 |
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