JPWO2020168291A5 - - Google Patents

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Publication number
JPWO2020168291A5
JPWO2020168291A5 JP2021547336A JP2021547336A JPWO2020168291A5 JP WO2020168291 A5 JPWO2020168291 A5 JP WO2020168291A5 JP 2021547336 A JP2021547336 A JP 2021547336A JP 2021547336 A JP2021547336 A JP 2021547336A JP WO2020168291 A5 JPWO2020168291 A5 JP WO2020168291A5
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JP
Japan
Prior art keywords
ribonucleic acid
sequence
engineered
engineered nuclease
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021547336A
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English (en)
Japanese (ja)
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JP2022520428A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/018432 external-priority patent/WO2020168291A1/en
Publication of JP2022520428A publication Critical patent/JP2022520428A/ja
Publication of JPWO2020168291A5 publication Critical patent/JPWO2020168291A5/ja
Priority to JP2023146414A priority Critical patent/JP7502537B2/ja
Ceased legal-status Critical Current

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JP2021547336A 2019-02-14 2020-02-14 Ruvcドメインを有する酵素 Ceased JP2022520428A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023146414A JP7502537B2 (ja) 2019-02-14 2023-09-08 Ruvcドメインを有する酵素

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962805899P 2019-02-14 2019-02-14
US201962805868P 2019-02-14 2019-02-14
US201962805878P 2019-02-14 2019-02-14
US62/805,868 2019-02-14
US62/805,899 2019-02-14
US62/805,878 2019-02-14
US201962874414P 2019-07-15 2019-07-15
US62/874,414 2019-07-15
PCT/US2020/018432 WO2020168291A1 (en) 2019-02-14 2020-02-14 Enzymes with ruvc domains

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023146414A Division JP7502537B2 (ja) 2019-02-14 2023-09-08 Ruvcドメインを有する酵素

Publications (2)

Publication Number Publication Date
JP2022520428A JP2022520428A (ja) 2022-03-30
JPWO2020168291A5 true JPWO2020168291A5 (ko) 2023-02-21

Family

ID=72045639

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021547336A Ceased JP2022520428A (ja) 2019-02-14 2020-02-14 Ruvcドメインを有する酵素
JP2023146414A Active JP7502537B2 (ja) 2019-02-14 2023-09-08 Ruvcドメインを有する酵素

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023146414A Active JP7502537B2 (ja) 2019-02-14 2023-09-08 Ruvcドメインを有する酵素

Country Status (9)

Country Link
US (1) US20240117330A1 (ko)
EP (1) EP3924482A4 (ko)
JP (2) JP2022520428A (ko)
KR (2) KR20240007322A (ko)
CN (2) CN113728098A (ko)
AU (2) AU2020223370B2 (ko)
CA (1) CA3130135A1 (ko)
MX (2) MX2021009886A (ko)
WO (1) WO2020168291A1 (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3130135A1 (en) 2019-02-14 2020-08-20 Metagenomi Ip Technologies, Llc Enzymes with ruvc domains
US10913941B2 (en) 2019-02-14 2021-02-09 Metagenomi Ip Technologies, Llc Enzymes with RuvC domains
GB2594339B (en) * 2020-02-14 2023-02-08 Metagenomi Inc Enzymes with RUVC domains
EP4114932A4 (en) 2020-03-06 2024-03-13 Metagenomi, Inc. CLASS II, TYPE V CRISPR SYSTEMS
MX2022012110A (es) * 2020-03-31 2022-10-18 Metagenomi Inc Sistemas crispr clase ii tipo ii.
WO2022056301A1 (en) * 2020-09-11 2022-03-17 Metagenomi Ip Technologies, Llc Base editing enzymes
WO2022098681A2 (en) * 2020-11-03 2022-05-12 Caspr Biotech Corporation Novel class 2 crispr-cas rna-guided endonucleases
KR20230134543A (ko) * 2021-01-22 2023-09-21 메타지노미, 인크. 신규한 조작된 뉴클레아제 및 키메라 뉴클레아제
WO2022159742A1 (en) * 2021-01-22 2022-07-28 Metagenomi, Inc Novel engineered and chimeric nucleases
WO2022232638A2 (en) * 2021-04-30 2022-11-03 Metagenomi, Inc. Enzymes with ruvc domains
WO2023122663A2 (en) * 2021-12-23 2023-06-29 Mammoth Biosciences, Inc. Effector proteins and methods of use
WO2023194359A1 (en) * 2022-04-04 2023-10-12 Alia Therapeutics Srl Compositions and methods for treatment of usher syndrome type 2a
WO2023245141A2 (en) * 2022-06-15 2023-12-21 Beam Therapeutics Inc. Compositions and methods for reducing complement activation
WO2024056880A2 (en) * 2022-09-16 2024-03-21 Alia Therapeutics Srl Enqp type ii cas proteins and applications thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201912327SA (en) * 2012-12-12 2020-02-27 Broad Inst Inc Engineering and Optimization of Improved Systems, Methods and Enzyme Compositions for Sequence Manipulation
US10392607B2 (en) * 2015-06-03 2019-08-27 The Regents Of The University Of California Cas9 variants and methods of use thereof
WO2016205759A1 (en) * 2015-06-18 2016-12-22 The Broad Institute Inc. Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation
WO2018035250A1 (en) * 2016-08-17 2018-02-22 The Broad Institute, Inc. Methods for identifying class 2 crispr-cas systems
CN112020554A (zh) * 2018-02-23 2020-12-01 先锋国际良种公司 新颖cas9直系同源物
CA3130135A1 (en) 2019-02-14 2020-08-20 Metagenomi Ip Technologies, Llc Enzymes with ruvc domains

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