JPWO2020150439A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2020150439A5
JPWO2020150439A5 JP2021541215A JP2021541215A JPWO2020150439A5 JP WO2020150439 A5 JPWO2020150439 A5 JP WO2020150439A5 JP 2021541215 A JP2021541215 A JP 2021541215A JP 2021541215 A JP2021541215 A JP 2021541215A JP WO2020150439 A5 JPWO2020150439 A5 JP WO2020150439A5
Authority
JP
Japan
Prior art keywords
alkyl
independently selected
optionally substituted
ring
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021541215A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022517797A (ja
JP2022517797A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/013824 external-priority patent/WO2020150439A1/en
Publication of JP2022517797A publication Critical patent/JP2022517797A/ja
Publication of JP2022517797A5 publication Critical patent/JP2022517797A5/ja
Publication of JPWO2020150439A5 publication Critical patent/JPWO2020150439A5/ja
Pending legal-status Critical Current

Links

JP2021541215A 2019-01-17 2020-01-16 Sting活性に関連する状態を治療するための化合物および組成物 Pending JP2022517797A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962793623P 2019-01-17 2019-01-17
US62/793,623 2019-01-17
US201962861702P 2019-06-14 2019-06-14
US62/861,702 2019-06-14
PCT/US2020/013824 WO2020150439A1 (en) 2019-01-17 2020-01-16 Compounds and compositions for treating conditions associated with sting activity

Publications (3)

Publication Number Publication Date
JP2022517797A JP2022517797A (ja) 2022-03-10
JP2022517797A5 JP2022517797A5 (https=) 2023-01-20
JPWO2020150439A5 true JPWO2020150439A5 (https=) 2023-01-20

Family

ID=69593778

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021541215A Pending JP2022517797A (ja) 2019-01-17 2020-01-16 Sting活性に関連する状態を治療するための化合物および組成物

Country Status (6)

Country Link
US (1) US20220388957A1 (https=)
EP (1) EP3911314A1 (https=)
JP (1) JP2022517797A (https=)
CN (1) CN113874010A (https=)
MA (1) MA54753A (https=)
WO (1) WO2020150439A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112823036B (zh) 2018-07-03 2024-11-08 艾福姆德尤股份有限公司 用于治疗与sting活性有关的疾病的化合物和组合物
CN112375027B (zh) * 2020-12-07 2023-03-31 中国药科大学 吲哚磺酰胺类衍生物及其医药用途
US20240060982A1 (en) 2020-12-22 2024-02-22 Ifm Due, Inc. Methods of treating cancer
WO2022140397A1 (en) 2020-12-22 2022-06-30 Ifm Due, Inc. Methods of treating cancer
EP4267128A1 (en) 2020-12-22 2023-11-01 IFM Due, Inc. Methods of treating cancer
EP4267129A1 (en) 2020-12-22 2023-11-01 IFM Due, Inc. Methods of treating cancer
TW202235073A (zh) 2021-01-08 2022-09-16 美商Ifm Due有限公司 用於治療與sting活性相關的病狀之化合物及組合物
UY39892A (es) 2021-08-10 2023-03-31 Novartis Pharma Ag Compuestos y composiciones para tratar afecciones asociadas con la actividad de STING
KR20250052376A (ko) * 2022-08-26 2025-04-18 에프. 호프만-라 로슈 아게 신규 중수소화 피리미딘-2-일 설폰아미드 유도체
WO2024064358A1 (en) 2022-09-23 2024-03-28 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0511993A1 (en) * 1990-01-22 1992-11-11 E.I. Du Pont De Nemours And Company Herbicidal sulfonylureas
US6521658B1 (en) * 1999-05-28 2003-02-18 Abbott Laboratories Cell proliferation inhibitors
AU2002306604B2 (en) * 2001-02-28 2007-09-13 Onconova Therapeutics, Inc. N-(Aryl)-2-arylethenesulfonamides and therapeutic uses thereof
CA2473803A1 (en) * 2002-02-01 2003-08-07 Robert Greenhouse Substituted indoles as alpha-1 agonists
US7927613B2 (en) 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
US7390670B2 (en) * 2003-02-20 2008-06-24 Lumigen, Inc. Signalling compounds and methods for detecting hydrogen peroxide
DK2142516T3 (da) * 2007-03-30 2013-04-15 Sanofi Sa Pyrimidinhydrazidforbindelser i ders egenskab af pgds-inhibitorer
WO2012075380A1 (en) 2010-12-03 2012-06-07 The Trustees Of The University Of Pennsylvania Tip60 inhibitors
CN109394752A (zh) 2013-10-21 2019-03-01 德雷克塞尔大学 治疗慢性乙型肝炎病毒感染的sting激动剂的用途
FR3017867A1 (fr) * 2014-02-21 2015-08-28 Inventiva Nouveaux composes de type phenylazetidine carboxylate ou carboxamide
AR106018A1 (es) * 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
WO2017153952A1 (en) * 2016-03-10 2017-09-14 Glaxosmithkline Intellectual Property Development Limited 5-sulfamoyl-2-hydroxybenzamide derivatives
US10858344B2 (en) * 2016-11-23 2020-12-08 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
TWI754702B (zh) * 2016-12-28 2022-02-11 德商Ucb製藥有限公司 (氮雜)吲哚-和苯並呋喃-3-磺醯胺類
CN112823036B (zh) * 2018-07-03 2024-11-08 艾福姆德尤股份有限公司 用于治疗与sting活性有关的疾病的化合物和组合物
US20210236466A1 (en) * 2018-07-03 2021-08-05 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
EP3883651A1 (en) * 2018-11-19 2021-09-29 IFM Due, Inc. Compounds and compositions for treating conditions associated with sting activity
US20230092163A1 (en) * 2019-06-14 2023-03-23 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
EP3983384B1 (en) * 2019-06-17 2023-10-11 UCB Pharma GmbH N-(phenyl)-indole-3-sulfonamide derivatives and related compounds as gpr17 modulators for treating cns disorders such as multiple sclerosis
CN114761804A (zh) * 2019-06-21 2022-07-15 艾福姆德尤股份有限公司 治疗癌症的方法

Similar Documents

Publication Publication Date Title
JP2021529833A5 (https=)
JP2021529834A5 (https=)
JPWO2020010092A5 (https=)
JP6839761B2 (ja) 抗PD−L1抗体との組み合わせのための抗Tim−3抗体
JP6839772B2 (ja) 抗PD−1抗体との組み合わせのための抗Tim−3抗体
ES2967467T3 (es) Combinación de una terapia celular y un compuesto inmunomodulador
US11623961B2 (en) Antibodies and chimeric antigen receptors specific for B-cell maturation antigen
US10973915B2 (en) Anti-PD-1 antibodies and uses thereof
TWI751979B (zh) 抗garp抗體
BR112021014833A2 (pt) Anticorpos e receptores antigênicos quiméricos específicos para receptor órfão 1 de tipo tirosina quinase de receptor (ror1)
CN111566484A (zh) 细胞外囊泡蛋白及其在癌症诊断、预测对疗法的反应和治疗中的用途
JP2019513809A5 (https=)
JPWO2020106736A5 (https=)
BR112020000209A2 (pt) moléculas de ligação que modulam uma atividade biológica expressa por uma célula
KR20240090979A (ko) Nkg2d, cd16, 및 trop2를 표적화하는 다중특이적 결합 단백질
JP2024023228A (ja) Manaボディおよび使用方法
JPWO2021138419A5 (https=)
JPWO2020010155A5 (https=)
KR102380150B1 (ko) Gitr 항체, 방법, 및 용도
WO2019030377A1 (en) CD96 BINDING AGENTS AS IMMUNOMODULATORS
BR112020000227A2 (pt) anticorpos biespecíficos anti pd1-anti tim3
KR20180016443A (ko) (z)-4-(5-((3-벤질-4-옥소-2-티옥소티아졸리딘-5-일리덴)메틸)푸란-2-일)벤조산의 고체형
JPWO2020150439A5 (https=)
US20240302349A1 (en) Methods of assessing or monitoring a response to a cell therapy
CN108699000B (zh) 用于抑制趋化因子活性及/或癌细胞生长的小分子