JPWO2020097566A5 - - Google Patents

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Publication number
JPWO2020097566A5
JPWO2020097566A5 JP2021524317A JP2021524317A JPWO2020097566A5 JP WO2020097566 A5 JPWO2020097566 A5 JP WO2020097566A5 JP 2021524317 A JP2021524317 A JP 2021524317A JP 2021524317 A JP2021524317 A JP 2021524317A JP WO2020097566 A5 JPWO2020097566 A5 JP WO2020097566A5
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JP
Japan
Prior art keywords
pharmaceutical composition
solid organ
months
subject
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021524317A
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English (en)
Japanese (ja)
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JP2022512937A (ja
JP2022512937A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/060622 external-priority patent/WO2020097566A1/en
Publication of JP2022512937A publication Critical patent/JP2022512937A/ja
Publication of JPWO2020097566A5 publication Critical patent/JPWO2020097566A5/ja
Publication of JP2022512937A5 publication Critical patent/JP2022512937A5/ja
Priority to JP2024135834A priority Critical patent/JP2024161505A/ja
Pending legal-status Critical Current

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JP2021524317A 2018-11-08 2019-11-08 Hla感作患者を脱感作し患者における腎移植を改善するためのクラザキズマブの使用 Pending JP2022512937A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024135834A JP2024161505A (ja) 2018-11-08 2024-08-16 Hla感作患者を脱感作し患者における腎移植を改善するためのクラザキズマブの使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862757676P 2018-11-08 2018-11-08
US62/757,676 2018-11-08
US201962855988P 2019-06-01 2019-06-01
US62/855,988 2019-06-01
PCT/US2019/060622 WO2020097566A1 (en) 2018-11-08 2019-11-08 Use of clazakizumab to desensitize and improve renal transplantation in hla-sensitized patients

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024135834A Division JP2024161505A (ja) 2018-11-08 2024-08-16 Hla感作患者を脱感作し患者における腎移植を改善するためのクラザキズマブの使用

Publications (3)

Publication Number Publication Date
JP2022512937A JP2022512937A (ja) 2022-02-07
JPWO2020097566A5 true JPWO2020097566A5 (https=) 2022-11-07
JP2022512937A5 JP2022512937A5 (https=) 2022-11-07

Family

ID=70612280

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021524317A Pending JP2022512937A (ja) 2018-11-08 2019-11-08 Hla感作患者を脱感作し患者における腎移植を改善するためのクラザキズマブの使用
JP2024135834A Pending JP2024161505A (ja) 2018-11-08 2024-08-16 Hla感作患者を脱感作し患者における腎移植を改善するためのクラザキズマブの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024135834A Pending JP2024161505A (ja) 2018-11-08 2024-08-16 Hla感作患者を脱感作し患者における腎移植を改善するためのクラザキズマブの使用

Country Status (9)

Country Link
US (1) US20210395358A1 (https=)
EP (1) EP3877412A4 (https=)
JP (2) JP2022512937A (https=)
KR (1) KR20210089719A (https=)
CN (1) CN112969711B (https=)
AU (1) AU2019374905A1 (https=)
BR (1) BR112021007633A2 (https=)
CA (1) CA3117386A1 (https=)
WO (1) WO2020097566A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8062864B2 (en) 2007-05-21 2011-11-22 Alderbio Holdings Llc Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
US20220073605A1 (en) * 2018-12-20 2022-03-10 Cedars-Sinai Medical Center Clazakizumab in the treatment of chronic antibody-mediated rejection of organ transplant
US20220288202A1 (en) * 2019-09-04 2022-09-15 Cedars-Sinai Medical Center Use of Calcineurin Inhibitor Free CTLA4-IG + Anti-IL6/IL6R For Long Term Immunosuppression in Solid Organ Transplant Recipients
KR20230009096A (ko) 2021-07-08 2023-01-17 주식회사 엘지에너지솔루션 리튬 이차전지용 양극 슬러리 조성물, 양극 및 이를 포함하는 리튬 이차전지

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
CA1292686C (en) 1986-10-27 1991-12-03 Ze'ev Shaked Pharmaceutical compositions of recombinant interleukin-2 and formulation process
CA1294215C (en) 1986-10-27 1992-01-14 Ze'ev Shaked Pharmaceutical compositions of recombinant beta-interferon and formulation processes
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US8062864B2 (en) 2007-05-21 2011-11-22 Alderbio Holdings Llc Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
HUE032563T2 (en) 2007-05-21 2017-09-28 Alderbio Holdings Llc Antibodies to IL-6 and their use
US9452227B2 (en) * 2008-11-25 2016-09-27 Alderbio Holdings Llc Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
US20110111437A1 (en) * 2009-10-08 2011-05-12 The University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biomarkers For Prognosis of Pulmonary Diseases
WO2011066374A2 (en) * 2009-11-24 2011-06-03 Alder Biopharmaceuticals, Inc. Antagonists of il-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
US20170174760A1 (en) * 2015-07-24 2017-06-22 Cedars-Sinai Medical Center Method for treating antibody-mediated rejection post-transplantation
US20200123238A1 (en) * 2017-04-19 2020-04-23 Alexion Pharmaceuticals, Inc. Efficacy of an anti-c5 antibody in the prevention of antibody mediated rejection in sensitized recipients of a kidney transplant

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