JPWO2020072814A5 - - Google Patents
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- Publication number
- JPWO2020072814A5 JPWO2020072814A5 JP2021518888A JP2021518888A JPWO2020072814A5 JP WO2020072814 A5 JPWO2020072814 A5 JP WO2020072814A5 JP 2021518888 A JP2021518888 A JP 2021518888A JP 2021518888 A JP2021518888 A JP 2021518888A JP WO2020072814 A5 JPWO2020072814 A5 JP WO2020072814A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- subject
- item
- day
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims description 93
- 150000001875 compounds Chemical class 0.000 claims description 45
- 150000003839 salts Chemical class 0.000 claims description 44
- 239000011780 sodium chloride Substances 0.000 claims description 44
- 230000035772 mutation Effects 0.000 claims description 34
- 102100009791 COL4A5 Human genes 0.000 claims description 17
- 101710038499 COL4A5 Proteins 0.000 claims description 17
- 102100009793 COL4A3 Human genes 0.000 claims description 15
- 101710038497 COL4A3 Proteins 0.000 claims description 15
- 206010011878 Deafness Diseases 0.000 claims description 12
- 208000004559 Hearing Loss Diseases 0.000 claims description 12
- 206010011879 Hearing loss Diseases 0.000 claims description 12
- 231100000888 hearing loss Toxicity 0.000 claims description 12
- 206010001843 Alport's syndrome Diseases 0.000 claims description 10
- 102100009792 COL4A4 Human genes 0.000 claims description 8
- 101710038504 COL4A4 Proteins 0.000 claims description 8
- 206010012601 Diabetes mellitus Diseases 0.000 claims description 7
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims description 7
- 208000001072 Type 2 Diabetes Mellitus Diseases 0.000 claims description 7
- 239000003814 drug Substances 0.000 claims description 7
- 230000001058 adult Effects 0.000 claims description 2
- 238000009472 formulation Methods 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 description 25
- 101700039191 EGFR Proteins 0.000 description 12
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- 229960005188 collagen Drugs 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 102000004266 Collagen Type IV Human genes 0.000 description 1
- 108010042086 Collagen Type IV Proteins 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862741270P | 2018-10-04 | 2018-10-04 | |
| US62/741,270 | 2018-10-04 | ||
| US201962853904P | 2019-05-29 | 2019-05-29 | |
| US62/853,904 | 2019-05-29 | ||
| US201962894559P | 2019-08-30 | 2019-08-30 | |
| US62/894,559 | 2019-08-30 | ||
| PCT/US2019/054559 WO2020072814A1 (en) | 2018-10-04 | 2019-10-03 | Biphenyl sulfonamide compounds for the treatment of type iv collagen diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022514152A JP2022514152A (ja) | 2022-02-10 |
| JPWO2020072814A5 true JPWO2020072814A5 (de) | 2022-10-06 |
Family
ID=68318947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021518888A Pending JP2022514152A (ja) | 2018-10-04 | 2019-10-03 | Ｉｖ型コラーゲン疾患の処置のためのビフェニルスルホンアミド化合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11207299B2 (de) |
| EP (1) | EP3860594A1 (de) |
| JP (1) | JP2022514152A (de) |
| KR (1) | KR20210081338A (de) |
| CN (1) | CN113286587A (de) |
| AU (1) | AU2019354784A1 (de) |
| BR (1) | BR112021006132A2 (de) |
| CA (1) | CA3114434A1 (de) |
| IL (1) | IL281965A (de) |
| MA (1) | MA53817A (de) |
| MX (1) | MX2021003606A (de) |
| WO (1) | WO2020072814A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117085013A (zh) | 2016-10-13 | 2023-11-21 | 特拉维尔治疗公司 | 用于治疗肾脏疾病或病症的联苯磺酰胺化合物 |
| WO2022246200A1 (en) * | 2021-05-21 | 2022-11-24 | Travere Therapeutics, Inc. | Methods of treating kidney diseases or disorders |
| WO2022266370A1 (en) * | 2021-06-17 | 2022-12-22 | Aria Pharmaceuticals, Inc. | Sparsentan for treating idiopathic pulmonary fibrosis |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK18822000A3 (sk) | 1998-07-06 | 2001-12-03 | Bristol-Myers Squibb Company | Bifenylsulfónamidy ako duálne antagonisty angiotenzínového a endotelínového receptora |
| US6638937B2 (en) | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| EP1237888B1 (de) | 1999-12-15 | 2006-09-13 | Bristol-Myers Squibb Company | Biphenyl - sulfonamide als duale angiotensin - endothelin - rezeptor - antagonisten |
| CN102421434A (zh) | 2009-03-31 | 2012-04-18 | 利亘制药公司 | 治疗高血压和糖尿病肾病的二苯基磺酰胺内皮素和血管紧张素ii受体激动剂的口服制剂 |
| WO2010135350A2 (en) | 2009-05-20 | 2010-11-25 | Pharmacopeia, Llc | Biphenyl intermediate compounds and methods for the preparation of a dual angiotensin ii and endothelin a receptor antagonist |
| US9719981B2 (en) | 2012-08-17 | 2017-08-01 | Father Flanagan's Boys' Home | RAC1 inhibitors for the treatment of alport glomerular disease |
| CN117085013A (zh) | 2016-10-13 | 2023-11-21 | 特拉维尔治疗公司 | 用于治疗肾脏疾病或病症的联苯磺酰胺化合物 |
| WO2020132594A1 (en) | 2018-12-21 | 2020-06-25 | Retrophin, Inc. | Amorphous sparsentan compositions |
-
2019
- 2019-10-03 MX MX2021003606A patent/MX2021003606A/es unknown
- 2019-10-03 CA CA3114434A patent/CA3114434A1/en active Pending
- 2019-10-03 MA MA053817A patent/MA53817A/fr unknown
- 2019-10-03 AU AU2019354784A patent/AU2019354784A1/en active Pending
- 2019-10-03 KR KR1020217010358A patent/KR20210081338A/ko unknown
- 2019-10-03 CN CN201980079773.4A patent/CN113286587A/zh active Pending
- 2019-10-03 EP EP19791401.3A patent/EP3860594A1/de active Pending
- 2019-10-03 JP JP2021518888A patent/JP2022514152A/ja active Pending
- 2019-10-03 BR BR112021006132-0A patent/BR112021006132A2/pt unknown
- 2019-10-03 US US16/592,633 patent/US11207299B2/en active Active
- 2019-10-03 WO PCT/US2019/054559 patent/WO2020072814A1/en unknown
-
2021
- 2021-04-01 IL IL281965A patent/IL281965A/en unknown
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