JPWO2020011976A5 - - Google Patents

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Publication number
JPWO2020011976A5
JPWO2020011976A5 JP2021500386A JP2021500386A JPWO2020011976A5 JP WO2020011976 A5 JPWO2020011976 A5 JP WO2020011976A5 JP 2021500386 A JP2021500386 A JP 2021500386A JP 2021500386 A JP2021500386 A JP 2021500386A JP WO2020011976 A5 JPWO2020011976 A5 JP WO2020011976A5
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JP
Japan
Prior art keywords
seq
nos
antibody molecule
domain
set forth
Prior art date
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Granted
Application number
JP2021500386A
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English (en)
Japanese (ja)
Other versions
JP2021524269A (ja
JP7360441B2 (ja
Publication date
Priority claimed from GBGB1811450.4A external-priority patent/GB201811450D0/en
Application filed filed Critical
Publication of JP2021524269A publication Critical patent/JP2021524269A/ja
Publication of JPWO2020011976A5 publication Critical patent/JPWO2020011976A5/ja
Priority to JP2023169048A priority Critical patent/JP2023178323A/ja
Application granted granted Critical
Publication of JP7360441B2 publication Critical patent/JP7360441B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021500386A 2018-07-12 2019-07-12 メソテリン及びcd137結合分子 Active JP7360441B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023169048A JP2023178323A (ja) 2018-07-12 2023-09-29 メソテリン及びcd137結合分子

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1811450.4 2018-07-12
GBGB1811450.4A GB201811450D0 (en) 2018-07-12 2018-07-12 Mesothelin and CD137 binding molecules
PCT/EP2019/068817 WO2020011976A1 (en) 2018-07-12 2019-07-12 Mesothelin and cd137 binding molecules

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023169048A Division JP2023178323A (ja) 2018-07-12 2023-09-29 メソテリン及びcd137結合分子

Publications (3)

Publication Number Publication Date
JP2021524269A JP2021524269A (ja) 2021-09-13
JPWO2020011976A5 true JPWO2020011976A5 (es) 2022-07-20
JP7360441B2 JP7360441B2 (ja) 2023-10-12

Family

ID=63273224

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021500386A Active JP7360441B2 (ja) 2018-07-12 2019-07-12 メソテリン及びcd137結合分子
JP2023169048A Pending JP2023178323A (ja) 2018-07-12 2023-09-29 メソテリン及びcd137結合分子

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023169048A Pending JP2023178323A (ja) 2018-07-12 2023-09-29 メソテリン及びcd137結合分子

Country Status (15)

Country Link
US (1) US20210309753A1 (es)
EP (1) EP3820894A1 (es)
JP (2) JP7360441B2 (es)
KR (1) KR20210030925A (es)
CN (1) CN112437776B (es)
AR (1) AR115769A1 (es)
AU (1) AU2019303081A1 (es)
BR (1) BR112021000396A2 (es)
CA (1) CA3103173A1 (es)
GB (1) GB201811450D0 (es)
IL (1) IL280007A (es)
MX (1) MX2021000397A (es)
SG (1) SG11202011960XA (es)
TW (1) TWI839365B (es)
WO (1) WO2020011976A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201612520D0 (en) 2016-07-19 2016-08-31 F-Star Beta Ltd Binding molecules
WO2019121906A1 (en) 2017-12-19 2019-06-27 F-Star Beta Limited Specific pd-l1 binding sequences inserted in a ch3 domain
MA52366A (fr) 2018-04-25 2021-03-03 Prometheus Biosciences Inc Anticorps anti-tl1a optimisés
GB201811408D0 (en) 2018-07-12 2018-08-29 F Star Beta Ltd CD137 Binding Molecules
WO2020081895A2 (en) * 2018-10-18 2020-04-23 The Scripps Research Institute Siv envelope trimer
AU2020371725A1 (en) 2019-10-24 2022-05-26 Cedars-Sinai Medical Center Humanized antibodies to TNF-like ligand 1A (TL1A) and uses thereof
WO2024039672A2 (en) * 2022-08-15 2024-02-22 Dana-Farber Cancer Institute, Inc. Antibodies against msln and methods of use thereof
WO2024042105A1 (en) 2022-08-26 2024-02-29 Merck Patent Gmbh Cancer treatment comprising an anti-msln/cd137 antibody and a chemotherapeutic
WO2024042104A1 (en) 2022-08-26 2024-02-29 Merck Patent Gmbh Combination cancer treatment comprising an anti-msln/cd137 antibody and pd-1/pd-l1 inhibitor

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61134325A (ja) 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
WO2000073346A1 (en) 1999-05-27 2000-12-07 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Immunoconjugates having high binding affinity
US7288638B2 (en) 2003-10-10 2007-10-30 Bristol-Myers Squibb Company Fully human antibodies against human 4-1BB
EA018897B1 (ru) 2005-01-05 2013-11-29 Ф-Стар Биотехнологише Форшунгс- Унд Энтвиклунгсгез.М.Б.Х. Молекулы иммуноглобулина, содержащие модифицированные участки структурных петель, обладающие свойством связывания, и способ их получения
KR101559599B1 (ko) 2007-11-26 2015-10-12 바이엘 인텔렉쳐 프로퍼티 게엠베하 항-메소텔린 항체 및 이의 용도
EP2113255A1 (en) 2008-05-02 2009-11-04 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Cytotoxic immunoglobulin
EP2900695B1 (en) * 2012-09-27 2018-01-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Mesothelin antibodies and methods for eliciting potent antitumor activity
KR101782487B1 (ko) * 2015-09-24 2017-09-27 재단법인 목암생명과학연구소 신규 항-메소텔린 항체 및 이를 포함하는 조성물
EP3445788B1 (en) * 2016-04-22 2022-01-19 Alligator Bioscience AB Novel bispecific polypeptides against cd137
TW201806972A (zh) * 2016-05-27 2018-03-01 美商艾伯維生物醫療股份有限公司 雙特異性結合蛋白
CN107523546A (zh) * 2016-06-20 2017-12-29 上海细胞治疗研究院 一种高效稳定表达抗体的nk细胞及其用途

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