JPWO2019246603A5 - - Google Patents
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- Publication number
- JPWO2019246603A5 JPWO2019246603A5 JP2021520287A JP2021520287A JPWO2019246603A5 JP WO2019246603 A5 JPWO2019246603 A5 JP WO2019246603A5 JP 2021520287 A JP2021520287 A JP 2021520287A JP 2021520287 A JP2021520287 A JP 2021520287A JP WO2019246603 A5 JPWO2019246603 A5 JP WO2019246603A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- halogen
- hydrogen
- compound
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862688612P | 2018-06-22 | 2018-06-22 | |
| US62/688,612 | 2018-06-22 | ||
| PCT/US2019/038622 WO2019246603A1 (fr) | 2018-06-22 | 2019-06-22 | Procédés et compositions pour inhiber la dihydroorotate déshydrogénase |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021530559A JP2021530559A (ja) | 2021-11-11 |
| JPWO2019246603A5 true JPWO2019246603A5 (fr) | 2022-06-30 |
| JP7373170B2 JP7373170B2 (ja) | 2023-11-02 |
Family
ID=68984309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021520287A Active JP7373170B2 (ja) | 2018-06-22 | 2019-06-22 | ジヒドロオロト酸デヒドロゲナーゼ阻害のための方法及び組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11312686B2 (fr) |
| EP (1) | EP3793562B1 (fr) |
| JP (1) | JP7373170B2 (fr) |
| KR (1) | KR20210048483A (fr) |
| CN (1) | CN112672744B (fr) |
| AU (2) | AU2019288813B2 (fr) |
| BR (1) | BR112020026308A2 (fr) |
| CA (1) | CA3103557A1 (fr) |
| IL (1) | IL279586B (fr) |
| MX (1) | MX2021000143A (fr) |
| SG (1) | SG11202012029PA (fr) |
| WO (1) | WO2019246603A1 (fr) |
| ZA (1) | ZA202007620B (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021519334A (ja) | 2018-03-26 | 2021-08-10 | クリア クリーク バイオ， インコーポレイテッド | ジヒドロオロト酸デヒドロゲナーゼを阻害するための組成物および方法 |
| CA3165512A1 (fr) * | 2019-12-26 | 2021-07-01 | Ohio State Innovation Foundation | Methodes et compositions pour inhiber la dihydroorotate deshydrogenase |
| US20230303710A1 (en) * | 2019-12-26 | 2023-09-28 | Ohio State Innovation Foundation | Methods and compositions for inhibition of dihydroorotate dehydrogenase in combination with an anti-cd38 therapeutic agent |
| JP2023518419A (ja) * | 2020-03-20 | 2023-05-01 | クリア クリーク バイオ， インコーポレイテッド | ブレキナルナトリウムの安定した多形性組成物ならびにその使用および製造方法 |
| WO2023091793A1 (fr) * | 2021-11-22 | 2023-05-25 | Ohio State Innovation Foundation | Procédés et compositions pour cibler un métabolisme alternatif conjointement avec des actions antileucémiques médiées par un inhibiteur de flt3 |
| CN115532290B (zh) * | 2022-10-13 | 2024-04-30 | 浙江昌海制药有限公司 | 一种特定晶面选择性氢化催化剂及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2888346A (en) * | 1955-08-22 | 1959-05-26 | Gen Aniline & Film Corp | Ultra-violet absorbing compounds |
| WO1997042953A1 (fr) | 1996-05-10 | 1997-11-20 | Novartis Ag | Utilisation de brequinar et de derives contre le rejet chronique de greffes allogeniques et la xenotransplantation |
| JP2003510352A (ja) | 1999-10-01 | 2003-03-18 | インスティチュート オブ モレキュラー アンド セル バイオロジー | ウイルス媒介性疾病の治療用化合物 |
| US6841561B1 (en) | 1999-10-01 | 2005-01-11 | Institute Of Molecular And Cell Biology | Dihydroorotate dehydrogenase inhibitors for the treatment of viral-mediated diseases |
| ME00055B (me) | 2002-05-17 | 2010-10-10 | Aventis Pharma Sa | Primjena docetaksel/doksorubicin/ciklofosfamida u adjuvantnoj terapiji raka dojke i jajnika |
| CA2898615A1 (fr) * | 2013-01-28 | 2014-07-31 | Viamet Pharmaceuticals, Inc. | Composes inhibiteurs de metalloenzyme |
| SI3019482T1 (sl) | 2013-02-25 | 2018-12-31 | Aurigene Discovery Technologies Limited | Derivati trisubstituiranega benzotriazola kot inhibitorji dihidroorotat oksigenaze |
-
2019
- 2019-06-22 CN CN201980042068.7A patent/CN112672744B/zh active Active
- 2019-06-22 AU AU2019288813A patent/AU2019288813B2/en active Active
- 2019-06-22 EP EP19822319.0A patent/EP3793562B1/fr active Active
- 2019-06-22 US US17/253,342 patent/US11312686B2/en active Active
- 2019-06-22 SG SG11202012029PA patent/SG11202012029PA/en unknown
- 2019-06-22 CA CA3103557A patent/CA3103557A1/fr active Pending
- 2019-06-22 JP JP2021520287A patent/JP7373170B2/ja active Active
- 2019-06-22 KR KR1020217002054A patent/KR20210048483A/ko unknown
- 2019-06-22 WO PCT/US2019/038622 patent/WO2019246603A1/fr active Search and Examination
- 2019-06-22 BR BR112020026308-7A patent/BR112020026308A2/pt not_active Application Discontinuation
- 2019-06-22 MX MX2021000143A patent/MX2021000143A/es unknown
-
2020
- 2020-12-07 ZA ZA2020/07620A patent/ZA202007620B/en unknown
- 2020-12-20 IL IL279586A patent/IL279586B/en unknown
-
2021
- 2021-11-10 US US17/523,675 patent/US11999697B2/en active Active
-
2023
- 2023-09-19 AU AU2023233065A patent/AU2023233065A1/en active Pending
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