ME00055B - Primjena docetaksel/doksorubicin/ciklofosfamida u adjuvantnoj terapiji raka dojke i jajnika - Google Patents

Primjena docetaksel/doksorubicin/ciklofosfamida u adjuvantnoj terapiji raka dojke i jajnika

Info

Publication number
ME00055B
ME00055B MEP-2008-163A MEP2008163A ME00055B ME 00055 B ME00055 B ME 00055B ME P2008163 A MEP2008163 A ME P2008163A ME 00055 B ME00055 B ME 00055B
Authority
ME
Montenegro
Prior art keywords
docetaxel
cyclophosphamide
doxorubicin
ovarian cancer
adjuvant therapy
Prior art date
Application number
MEP-2008-163A
Other languages
English (en)
Inventor
Hichem Chakroun
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of ME00055B publication Critical patent/ME00055B/me

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Ovaj pronalazak se odnosi na novi metod adjuvantne terapije u lečenju metastaznog raka dojke ili raka jajnika, koji obuhvata administriranje šest ciklusa docetaksela, doksorubicina i ciklofosfamida obolelom pacijentu, pri čemu doze imaju naznačen terapeutski efekat u poređenju sa drugim tadjuvantnim terapijama.
MEP-2008-163A 2002-05-17 2003-05-15 Primjena docetaksel/doksorubicin/ciklofosfamida u adjuvantnoj terapiji raka dojke i jajnika ME00055B (me)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38085002P 2002-05-17 2002-05-17
PCT/EP2003/007443 WO2003097164A1 (en) 2002-05-17 2003-05-15 Use of docetaxel/doxorubicin/cyclophosphamide in adjuvant therapy of breast and ovarian cancer

Publications (1)

Publication Number Publication Date
ME00055B true ME00055B (me) 2010-10-10

Family

ID=29550025

Family Applications (2)

Application Number Title Priority Date Filing Date
MEP-163/08A MEP16308A (en) 2002-05-17 2003-05-15 Use of docetaxel/doxorubicin/cyclophosphamide in adjuvant therapy of breast and ovarian cancer
MEP-2008-163A ME00055B (me) 2002-05-17 2003-05-15 Primjena docetaksel/doksorubicin/ciklofosfamida u adjuvantnoj terapiji raka dojke i jajnika

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MEP-163/08A MEP16308A (en) 2002-05-17 2003-05-15 Use of docetaxel/doxorubicin/cyclophosphamide in adjuvant therapy of breast and ovarian cancer

Country Status (28)

Country Link
US (2) US20040014694A1 (me)
EP (1) EP1507573A1 (me)
JP (1) JP4773719B2 (me)
KR (1) KR20050000544A (me)
CN (1) CN1652845A (me)
AU (1) AU2003244646B2 (me)
BR (1) BR0310026A (me)
CA (1) CA2486124A1 (me)
CR (1) CR7575A (me)
EC (1) ECSP045433A (me)
HR (1) HRPK20041072B3 (me)
IL (1) IL165214A0 (me)
MA (1) MA27417A1 (me)
ME (2) MEP16308A (me)
MX (1) MXPA04010640A (me)
MY (1) MY146533A (me)
NO (1) NO20045370L (me)
NZ (1) NZ535992A (me)
OA (1) OA12819A (me)
PA (1) PA8574001A1 (me)
RS (1) RS96304A (me)
RU (1) RU2321396C2 (me)
TN (1) TNSN04217A1 (me)
TW (1) TWI374741B (me)
UA (1) UA81628C2 (me)
UY (1) UY27812A1 (me)
WO (1) WO2003097164A1 (me)
ZA (1) ZA200408549B (me)

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ES2425083T3 (es) * 2003-09-25 2013-10-11 Astellas Pharma Inc. Agente antitumoral que comprende FK228 como inhibidor de histona desacetilasa y doxorrubicina como inhibidor de topoisomerasa II
GB0326486D0 (en) * 2003-11-14 2003-12-17 Pharma Mar Sau Combination treatment
JP2006316040A (ja) 2005-05-13 2006-11-24 Genentech Inc Ｈｅｒｃｅｐｔｉｎ（登録商標）補助療法
WO2008027988A2 (en) * 2006-08-31 2008-03-06 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods of treating estrogen-responsive conditions by orphan nuclear receptor activation
HUE047357T2 (hu) * 2011-04-01 2020-04-28 Astrazeneca Ab Gyógyászati kezelés
KR102035361B1 (ko) 2011-11-30 2019-11-08 아스트라제네카 아베 암의 병용 치료
AU2013204533B2 (en) 2012-04-17 2017-02-02 Astrazeneca Ab Crystalline forms
US20160067182A1 (en) * 2013-04-09 2016-03-10 Merrimack Pharmaceuticals, Inc. Methods and compositions for improving outcomes of liposomal chemotherapy
CA2946860A1 (en) 2014-04-25 2015-10-29 Genentech, Inc. Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab
US10849916B2 (en) 2014-07-11 2020-12-01 Dr. Reddys Laboratories Limited Stable liquid formulations of cyclophosphamide and its impurities
WO2016005962A2 (en) 2014-07-11 2016-01-14 Dr. Reddy’S Laboratories Limited Stable liquid formulations of cyclophosphamide and processes
MY190034A (en) 2015-03-06 2022-03-22 Beyondspring Pharmaceuticals Inc Method of treating cancer associated with a ras mutation
PE20180528A1 (es) 2015-07-13 2018-03-19 Beyondspring Pharmaceuticals Inc Composiciones de plinabulina
US20190054019A1 (en) * 2015-10-22 2019-02-21 Universidade De Santiago De Compostela Methods for using regulators for increasing the expression or activation of p53 and/or regulators for reducing or inhibiting the expression of p63-alpha, for the treatment of non-alcoholic fatty liver disease (nafld) and/or non-alcoholic steatohepatitis (nash)
MX2018009413A (es) 2016-02-08 2019-05-15 Beyondspring Pharmaceuticals Inc Composiciones que contienen tucaresol o sus analogos.
WO2018039452A1 (en) * 2016-08-24 2018-03-01 The Wistar Institute Of Anatomy And Biology Methods of treating cancers with chemotherapy with reduced toxicity
US11491147B2 (en) * 2016-10-03 2022-11-08 Indiana University Research And Technology Corporation Combination drug therapy reduces PARP-1 related DNA repair and increases the efficacy of genotoxic agents
EP3565812B1 (en) 2017-01-06 2023-12-27 Beyondspring Pharmaceuticals, Inc. Tubulin binding compounds and therapeutic use thereof
BR112019015974A2 (pt) 2017-02-01 2020-03-31 Beyondspring Pharmaceuticals, Inc. Método para reduzir neutropenia
CN116531511A (zh) 2017-03-02 2023-08-04 豪夫迈·罗氏有限公司 Her2阳性乳腺癌的辅助治疗
KR20200112881A (ko) 2018-01-24 2020-10-05 비욘드스프링 파마수티컬스, 인코포레이티드. 플리나불린의 투여를 통해 혈소판감소증을 감소시키는 조성물 및 방법
AU2019288813B2 (en) * 2018-06-22 2023-06-29 Hendrix College Methods and compositions for inhibition of dihydroorotate dehydrogenase
CN115969792A (zh) * 2023-01-29 2023-04-18 常州金远药业制造有限公司 一种紫杉烷类药物与环磷酰胺共载载药脂质体制备方法

Family Cites Families (10)

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FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
US6441026B1 (en) * 1993-11-08 2002-08-27 Aventis Pharma S.A. Antitumor compositions containing taxane derivatives
US5565478A (en) * 1994-03-14 1996-10-15 The United States Of America As Represented By The Department Of Health & Human Services Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs
US6262054B1 (en) * 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
US6323205B1 (en) * 1996-07-17 2001-11-27 Sloan-Kettering Institute For Cancer Research Combinations of 10-propargyl-10-deazaaminopterin and taxols and methods of using same in the treatment of tumors
US6541508B2 (en) * 1999-09-13 2003-04-01 Nobex Corporation Taxane prodrugs
TWI310684B (en) * 2000-03-27 2009-06-11 Bristol Myers Squibb Co Synergistic pharmaceutical kits for treating cancer
US20020128228A1 (en) * 2000-12-01 2002-09-12 Wen-Jen Hwu Compositions and methods for the treatment of cancer

Also Published As

Publication number Publication date
CN1652845A (zh) 2005-08-10
NZ535992A (en) 2008-11-28
OA12819A (en) 2006-07-10
EP1507573A1 (en) 2005-02-23
UY27812A1 (es) 2003-11-28
HRP20041072A2 (en) 2005-06-30
RU2321396C2 (ru) 2008-04-10
MEP16308A (en) 2010-06-10
WO2003097164A1 (en) 2003-11-27
RS96304A (en) 2006-10-27
BR0310026A (pt) 2005-02-15
UA81628C2 (uk) 2008-01-25
US20070265213A1 (en) 2007-11-15
TNSN04217A1 (en) 2007-03-12
US20040014694A1 (en) 2004-01-22
CA2486124A1 (en) 2003-11-27
JP4773719B2 (ja) 2011-09-14
KR20050000544A (ko) 2005-01-05
IL165214A0 (en) 2005-12-18
TWI374741B (en) 2012-10-21
JP2005529925A (ja) 2005-10-06
TW200407152A (en) 2004-05-16
AU2003244646A1 (en) 2003-12-02
NO20045370L (no) 2004-12-08
AU2003244646B2 (en) 2008-08-07
MY146533A (en) 2012-08-15
MXPA04010640A (es) 2005-08-16
MA27417A1 (fr) 2005-07-01
CR7575A (es) 2006-05-10
RU2004136984A (ru) 2005-06-27
ZA200408549B (en) 2006-01-25
PA8574001A1 (es) 2003-12-19
HRPK20041072B3 (en) 2007-07-31
ECSP045433A (es) 2005-01-03

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