JPWO2019195452A5 - - Google Patents

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Publication number
JPWO2019195452A5
JPWO2019195452A5 JP2020554172A JP2020554172A JPWO2019195452A5 JP WO2019195452 A5 JPWO2019195452 A5 JP WO2019195452A5 JP 2020554172 A JP2020554172 A JP 2020554172A JP 2020554172 A JP2020554172 A JP 2020554172A JP WO2019195452 A5 JPWO2019195452 A5 JP WO2019195452A5
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JP
Japan
Prior art keywords
cancer
less
antibody
antigen
cell
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JP2020554172A
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English (en)
Japanese (ja)
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JP2021520201A (ja
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Priority claimed from PCT/US2019/025623 external-priority patent/WO2019195452A1/en
Publication of JP2021520201A publication Critical patent/JP2021520201A/ja
Publication of JPWO2019195452A5 publication Critical patent/JPWO2019195452A5/ja
Pending legal-status Critical Current

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JP2020554172A 2018-04-04 2019-04-03 抗cd27抗体およびその使用 Pending JP2021520201A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862652790P 2018-04-04 2018-04-04
US62/652,790 2018-04-04
PCT/US2019/025623 WO2019195452A1 (en) 2018-04-04 2019-04-03 Anti-cd27 antibodies and uses thereof

Publications (2)

Publication Number Publication Date
JP2021520201A JP2021520201A (ja) 2021-08-19
JPWO2019195452A5 true JPWO2019195452A5 (zh) 2022-04-12

Family

ID=66175569

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020554172A Pending JP2021520201A (ja) 2018-04-04 2019-04-03 抗cd27抗体およびその使用

Country Status (6)

Country Link
US (1) US12110337B2 (zh)
EP (1) EP3774903A1 (zh)
JP (1) JP2021520201A (zh)
KR (1) KR20200140315A (zh)
CN (1) CN112292399A (zh)
WO (1) WO2019195452A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101339628B1 (ko) * 2005-05-09 2013-12-09 메다렉스, 인코포레이티드 예정 사멸 인자 1(pd-1)에 대한 인간 모노클로날 항체, 및 항-pd-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법
US20230242624A1 (en) 2020-06-02 2023-08-03 Neurimmune Ag HUMAN ANTIBODIES AGAINST SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 (SARS-CoV-2)
JP2023535610A (ja) * 2020-07-28 2023-08-18 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル ガンを予防及び処置するための方法及び組成物
CN112194723B (zh) * 2020-09-25 2021-09-21 广州百吉生物制药有限公司 一种免疫细胞在治疗癌症中应用
TW202328192A (zh) 2021-09-06 2023-07-16 荷蘭商珍美寶公司 能結合cd27之抗體、彼之變異體及彼等之用途
AU2023236289A1 (en) 2022-03-15 2024-08-15 Compugen Ltd. Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer
WO2023218051A1 (en) 2022-05-12 2023-11-16 Genmab A/S Binding agents capable of binding to cd27 in combination therapy
WO2023218046A1 (en) 2022-05-12 2023-11-16 Genmab A/S Binding agents capable of binding to cd27 in combination therapy

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1210428T3 (en) 1999-08-23 2015-06-15 Dana Farber Cancer Inst Inc PD-1, a receptor for B7-4 AND USE THEREOF
JP4511943B2 (ja) 2002-12-23 2010-07-28 ワイス エルエルシー Pd−1に対する抗体およびその使用
NZ542873A (en) 2003-03-05 2008-07-31 Halozyme Inc Soluble, neutral-active hyaluronidase activity glycoprotein (sHASEGP) that is produced with high yield in a mammalian expression system by introducing nucleic acids that lack a narrow region encoding amino acids in the carboxy terminus of the human PH20 cDNA
KR101339628B1 (ko) 2005-05-09 2013-12-09 메다렉스, 인코포레이티드 예정 사멸 인자 1(pd-1)에 대한 인간 모노클로날 항체, 및 항-pd-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법
DK1907424T3 (en) 2005-07-01 2015-11-09 Squibb & Sons Llc HUMAN MONOCLONAL ANTIBODIES TO PROGRAMMED death ligand 1 (PD-L1)
GB0620894D0 (en) * 2006-10-20 2006-11-29 Univ Southampton Human immune therapies using a CD27 agonist alone or in combination with other immune modulators
BRPI0812913B8 (pt) 2007-06-18 2021-05-25 Merck Sharp & Dohme anticorpos monoclonais ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotideo, método para produzir os referidos anticorpos ou fragmentos de anticorpos, composição que os compreende e uso dos mesmos
US8168757B2 (en) 2008-03-12 2012-05-01 Merck Sharp & Dohme Corp. PD-1 binding proteins
CN114835812A (zh) 2008-12-09 2022-08-02 霍夫曼-拉罗奇有限公司 抗-pd-l1抗体及它们用于增强t细胞功能的用途
HUE049647T2 (hu) 2009-11-24 2020-09-28 Medimmune Ltd Targetált kötõdõ ágensek B7-H1 ellen
US9169325B2 (en) * 2010-04-13 2015-10-27 Celldex Therapeutics, Inc. Antibodies that bind human CD27 and uses thereof
CA2804550C (en) * 2010-07-09 2021-01-05 Bionovion Holding B.V. Agonistic antibody to cd27
RU2625034C2 (ru) 2011-04-20 2017-07-11 МЕДИММЬЮН, ЭлЭлСи Антитела и другие молекулы, которые связывают в7-н1 и pd-1
SG11201402603WA (en) 2011-11-28 2014-06-27 Merck Patent Gmbh Anti-pd-l1 antibodies and uses thereof
CA2867299C (en) * 2012-03-15 2019-08-27 John Chen Human anti-cd27 antibodies, methods, and uses
BR112014028826B1 (pt) 2012-05-15 2024-04-30 Bristol-Myers Squibb Company Uso de nivolumab ou pembrolizumabe
KR102284247B1 (ko) 2012-05-31 2021-08-03 소렌토 쎄라퓨틱스, 인코포레이티드 Pd-l1에 결합하는 항원 결합 단백질
CA2910278C (en) 2013-05-02 2021-09-28 Anaptysbio, Inc. Antibodies directed against programmed death-1 (pd-1)
EP3004169B1 (en) 2013-05-31 2023-03-22 Sorrento Therapeutics, Inc. Antigen binding proteins that bind pd-1
CN104250302B (zh) 2013-06-26 2017-11-14 上海君实生物医药科技股份有限公司 抗pd‑1抗体及其应用
ES2927567T3 (es) 2013-09-13 2022-11-08 Beigene Switzerland Gmbh Anticuerpos anti-PD1 y su uso como productos terapéuticos y de diagnóstico
JP6502959B2 (ja) 2013-12-12 2019-04-17 上海恒瑞医薬有限公司 Pd−1抗体、その抗原結合性断片及びそれらの医学的使用
TWI680138B (zh) 2014-01-23 2019-12-21 美商再生元醫藥公司 抗pd-l1之人類抗體
TWI681969B (zh) 2014-01-23 2020-01-11 美商再生元醫藥公司 針對pd-1的人類抗體
JOP20200094A1 (ar) 2014-01-24 2017-06-16 Dana Farber Cancer Inst Inc جزيئات جسم مضاد لـ pd-1 واستخداماتها
WO2016081748A2 (en) * 2014-11-21 2016-05-26 Bristol-Myers Squibb Company Antibodies against cd73 and uses thereof
EP3237446B1 (en) 2014-12-22 2021-05-05 PD-1 Acquisition Group, LLC Anti-pd-1 antibodies
WO2016145085A2 (en) * 2015-03-09 2016-09-15 Celldex Therapeutics, Inc. Cd27 agonists
MX2017011644A (es) 2015-03-13 2017-12-04 Cytomx Therapeutics Inc Anticuerpos anti-pdl1, anticuerpos anti-pdl1 activables y metodos de uso de los mismos.
BR112017021688A2 (pt) * 2015-04-17 2018-08-14 Bristol-Myers Squibb Company composições compreendendo uma combinação de um anticorpo anti-pd-1 e outro anticorpo
US10696745B2 (en) 2015-06-11 2020-06-30 Wuxi Biologics (Shanghai) Co. Ltd. Anti-PD-L1 antibodies
WO2017020291A1 (en) 2015-08-06 2017-02-09 Wuxi Biologics (Shanghai) Co. Ltd. Novel anti-pd-l1 antibodies
WO2017024465A1 (en) 2015-08-10 2017-02-16 Innovent Biologics (Suzhou) Co., Ltd. Pd-1 antibodies
EP3334763B1 (en) 2015-08-11 2024-08-07 WuXi Biologics Ireland Limited Novel anti-pd-1 antibodies
WO2017024515A1 (en) 2015-08-11 2017-02-16 Wuxi Biologics (Cayman) Inc. Novel anti-pd-1 antibodies
AR105654A1 (es) 2015-08-24 2017-10-25 Lilly Co Eli Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
CN107949573B (zh) 2015-09-01 2022-05-03 艾吉纳斯公司 抗-pd-1抗体及其使用方法
MX2018007089A (es) 2015-12-14 2019-01-30 Macrogenics Inc Moleculas biespecificas que tienen inmunorreactividad con pd-1 y ctla-4, y metodos de uso de las mismas.
KR20180101417A (ko) 2016-01-11 2018-09-12 아르모 바이오사이언시스 인코포레이티드 항원-특이적 cd8+ t 세포의 제조에서 인터루킨-10 및 이의 사용 방법
WO2017132827A1 (en) 2016-02-02 2017-08-10 Innovent Biologics (Suzhou) Co., Ltd. Pd-1 antibodies
JOP20190055A1 (ar) * 2016-09-26 2019-03-24 Merck Sharp & Dohme أجسام مضادة ضد cd27

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