JPWO2019177138A5 - - Google Patents
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- JPWO2019177138A5 JPWO2019177138A5 JP2020506667A JP2020506667A JPWO2019177138A5 JP WO2019177138 A5 JPWO2019177138 A5 JP WO2019177138A5 JP 2020506667 A JP2020506667 A JP 2020506667A JP 2020506667 A JP2020506667 A JP 2020506667A JP WO2019177138 A5 JPWO2019177138 A5 JP WO2019177138A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody fragment
- acid sequence
- amino acid
- seq
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018049752 | 2018-03-16 | ||
| JP2018049752 | 2018-03-16 | ||
| PCT/JP2019/010771 WO2019177138A1 (ja) | 2018-03-16 | 2019-03-15 | 異常tdp-43を分解除去する抗体断片 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2019177138A1 JPWO2019177138A1 (ja) | 2021-05-13 |
| JPWO2019177138A5 true JPWO2019177138A5 (https=) | 2022-02-24 |
| JP7320282B2 JP7320282B2 (ja) | 2023-08-03 |
Family
ID=67906698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020506667A Active JP7320282B2 (ja) | 2018-03-16 | 2019-03-15 | 異常tdp-43を分解除去する抗体断片 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12215142B2 (https=) |
| EP (1) | EP3770262B1 (https=) |
| JP (1) | JP7320282B2 (https=) |
| CN (1) | CN112236523A (https=) |
| WO (1) | WO2019177138A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021222168A2 (en) | 2020-04-28 | 2021-11-04 | Sola Biosciences Llc | Compositions and methods for the treatment of tdp-43 proteinopathies |
| WO2022163438A1 (ja) * | 2021-01-26 | 2022-08-04 | 株式会社ニコン | 神経細胞の解析方法、神経細胞の解析装置およびコンピュータプログラム |
| US20250258180A1 (en) | 2021-07-27 | 2025-08-14 | Stand Therapeutics Co., Ltd. | Peptide tag and nucleic acid encoding same |
| WO2023204313A1 (ja) | 2022-04-22 | 2023-10-26 | 国立大学法人新潟大学 | Tdp-43の凝集抑制剤及び医薬組成物 |
| CN115894690B (zh) * | 2022-11-30 | 2025-06-13 | 浙江大学 | 一种抗体降解子及其应用 |
| CN116410311B (zh) * | 2023-03-22 | 2023-12-12 | 暨南大学 | 胞内抗体及其制备方法和用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8940872B2 (en) | 2007-07-06 | 2015-01-27 | Tokyo Metropolitan Institute Of Medical Science | Antibody binding specifically to TDP-43 aggregate |
| TWI452136B (zh) * | 2010-11-17 | 2014-09-11 | 中外製藥股份有限公司 | A multiple specific antigen-binding molecule that replaces the function of Factor VIII in blood coagulation |
| US8790651B2 (en) * | 2011-07-21 | 2014-07-29 | Zoetis Llc | Interleukin-31 monoclonal antibody |
| US9587014B2 (en) | 2011-10-28 | 2017-03-07 | Biogen International Neuroscience Gmbh | TDP-43 specific binding molecules |
| JP5971966B2 (ja) * | 2012-02-13 | 2016-08-17 | 国立大学法人滋賀医科大学 | Tdp−43の凝集体が蓄積する疾患の発症リスクを予測する方法、診断薬及び治療薬 |
| JP6332723B2 (ja) | 2013-03-08 | 2018-05-30 | 国立大学法人滋賀医科大学 | Tdp−43の凝集体が蓄積する疾患を治療及び/又は予防するための化合物のスクリーニング方法 |
| WO2016053610A1 (en) * | 2014-10-03 | 2016-04-07 | Academia Sinica | Antibodies against pathological forms of tdp-43 and uses thereof |
| RU2693661C2 (ru) | 2016-03-04 | 2019-07-03 | Сычуань Келунь-Байотек Байофармасьютикал Ко., Лтд. | Антитело против pdl-1, его фармацевтическая композиция и применение |
-
2019
- 2019-03-15 EP EP19768492.1A patent/EP3770262B1/en active Active
- 2019-03-15 JP JP2020506667A patent/JP7320282B2/ja active Active
- 2019-03-15 WO PCT/JP2019/010771 patent/WO2019177138A1/ja not_active Ceased
- 2019-03-15 CN CN201980027565.XA patent/CN112236523A/zh active Pending
- 2019-03-15 US US16/980,667 patent/US12215142B2/en active Active
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