JPWO2019177138A5 - - Google Patents

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Publication number
JPWO2019177138A5
JPWO2019177138A5 JP2020506667A JP2020506667A JPWO2019177138A5 JP WO2019177138 A5 JPWO2019177138 A5 JP WO2019177138A5 JP 2020506667 A JP2020506667 A JP 2020506667A JP 2020506667 A JP2020506667 A JP 2020506667A JP WO2019177138 A5 JPWO2019177138 A5 JP WO2019177138A5
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JP
Japan
Prior art keywords
antibody fragment
acid sequence
amino acid
seq
therapeutic agent
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JP2020506667A
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English (en)
Japanese (ja)
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JP7320282B2 (ja
JPWO2019177138A1 (ja
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Priority claimed from PCT/JP2019/010771 external-priority patent/WO2019177138A1/ja
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Publication of JPWO2019177138A5 publication Critical patent/JPWO2019177138A5/ja
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JP2020506667A 2018-03-16 2019-03-15 異常tdp-43を分解除去する抗体断片 Active JP7320282B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018049752 2018-03-16
JP2018049752 2018-03-16
PCT/JP2019/010771 WO2019177138A1 (ja) 2018-03-16 2019-03-15 異常tdp-43を分解除去する抗体断片

Publications (3)

Publication Number Publication Date
JPWO2019177138A1 JPWO2019177138A1 (ja) 2021-05-13
JPWO2019177138A5 true JPWO2019177138A5 (https=) 2022-02-24
JP7320282B2 JP7320282B2 (ja) 2023-08-03

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ID=67906698

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JP2020506667A Active JP7320282B2 (ja) 2018-03-16 2019-03-15 異常tdp-43を分解除去する抗体断片

Country Status (5)

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US (1) US12215142B2 (https=)
EP (1) EP3770262B1 (https=)
JP (1) JP7320282B2 (https=)
CN (1) CN112236523A (https=)
WO (1) WO2019177138A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021222168A2 (en) 2020-04-28 2021-11-04 Sola Biosciences Llc Compositions and methods for the treatment of tdp-43 proteinopathies
WO2022163438A1 (ja) * 2021-01-26 2022-08-04 株式会社ニコン 神経細胞の解析方法、神経細胞の解析装置およびコンピュータプログラム
US20250258180A1 (en) 2021-07-27 2025-08-14 Stand Therapeutics Co., Ltd. Peptide tag and nucleic acid encoding same
WO2023204313A1 (ja) 2022-04-22 2023-10-26 国立大学法人新潟大学 Tdp-43の凝集抑制剤及び医薬組成物
CN115894690B (zh) * 2022-11-30 2025-06-13 浙江大学 一种抗体降解子及其应用
CN116410311B (zh) * 2023-03-22 2023-12-12 暨南大学 胞内抗体及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8940872B2 (en) 2007-07-06 2015-01-27 Tokyo Metropolitan Institute Of Medical Science Antibody binding specifically to TDP-43 aggregate
TWI452136B (zh) * 2010-11-17 2014-09-11 中外製藥股份有限公司 A multiple specific antigen-binding molecule that replaces the function of Factor VIII in blood coagulation
US8790651B2 (en) * 2011-07-21 2014-07-29 Zoetis Llc Interleukin-31 monoclonal antibody
US9587014B2 (en) 2011-10-28 2017-03-07 Biogen International Neuroscience Gmbh TDP-43 specific binding molecules
JP5971966B2 (ja) * 2012-02-13 2016-08-17 国立大学法人滋賀医科大学 Tdp−43の凝集体が蓄積する疾患の発症リスクを予測する方法、診断薬及び治療薬
JP6332723B2 (ja) 2013-03-08 2018-05-30 国立大学法人滋賀医科大学 Tdp−43の凝集体が蓄積する疾患を治療及び/又は予防するための化合物のスクリーニング方法
WO2016053610A1 (en) * 2014-10-03 2016-04-07 Academia Sinica Antibodies against pathological forms of tdp-43 and uses thereof
RU2693661C2 (ru) 2016-03-04 2019-07-03 Сычуань Келунь-Байотек Байофармасьютикал Ко., Лтд. Антитело против pdl-1, его фармацевтическая композиция и применение

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