JPWO2018191748A5 - - Google Patents

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JPWO2018191748A5
JPWO2018191748A5 JP2019555484A JP2019555484A JPWO2018191748A5 JP WO2018191748 A5 JPWO2018191748 A5 JP WO2018191748A5 JP 2019555484 A JP2019555484 A JP 2019555484A JP 2019555484 A JP2019555484 A JP 2019555484A JP WO2018191748 A5 JPWO2018191748 A5 JP WO2018191748A5
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JP
Japan
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car
seq
cell
antigen
composition
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JP2019555484A
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English (en)
Japanese (ja)
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JP7505885B2 (ja
JP2020516276A (ja
JP2020516276A5 (zh
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Priority claimed from PCT/US2018/027783 external-priority patent/WO2018191748A1/en
Publication of JP2020516276A publication Critical patent/JP2020516276A/ja
Publication of JP2020516276A5 publication Critical patent/JP2020516276A5/ja
Publication of JPWO2018191748A5 publication Critical patent/JPWO2018191748A5/ja
Priority to JP2024014208A priority Critical patent/JP2024062986A/ja
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Publication of JP7505885B2 publication Critical patent/JP7505885B2/ja
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JP2019555484A 2017-04-14 2018-04-16 腫瘍微小環境を標的にするキメラ抗原受容体t細胞 Active JP7505885B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024014208A JP2024062986A (ja) 2017-04-14 2024-02-01 腫瘍微小環境を標的にするキメラ抗原受容体t細胞

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762485670P 2017-04-14 2017-04-14
US62/485,670 2017-04-14
US201862629593P 2018-02-12 2018-02-12
US62/629,593 2018-02-12
PCT/US2018/027783 WO2018191748A1 (en) 2017-04-14 2018-04-16 Chimeric antigen receptor t cells targeting the tumor microenvironment

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024014208A Division JP2024062986A (ja) 2017-04-14 2024-02-01 腫瘍微小環境を標的にするキメラ抗原受容体t細胞

Publications (4)

Publication Number Publication Date
JP2020516276A JP2020516276A (ja) 2020-06-11
JP2020516276A5 JP2020516276A5 (zh) 2021-05-27
JPWO2018191748A5 true JPWO2018191748A5 (zh) 2023-10-26
JP7505885B2 JP7505885B2 (ja) 2024-06-25

Family

ID=63793633

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019555484A Active JP7505885B2 (ja) 2017-04-14 2018-04-16 腫瘍微小環境を標的にするキメラ抗原受容体t細胞
JP2024014208A Pending JP2024062986A (ja) 2017-04-14 2024-02-01 腫瘍微小環境を標的にするキメラ抗原受容体t細胞

Family Applications After (1)

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JP2024014208A Pending JP2024062986A (ja) 2017-04-14 2024-02-01 腫瘍微小環境を標的にするキメラ抗原受容体t細胞

Country Status (7)

Country Link
US (2) US20200113940A1 (zh)
EP (1) EP3609914A4 (zh)
JP (2) JP7505885B2 (zh)
CN (1) CN110520524A (zh)
AU (2) AU2018251206A1 (zh)
CA (1) CA3059444A1 (zh)
WO (1) WO2018191748A1 (zh)

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US20210038646A1 (en) * 2018-02-12 2021-02-11 The General Hospital Corporation Chimeric antigen receptors targeting the tumor microenvironment
WO2020020359A1 (en) * 2018-07-26 2020-01-30 Nanjing Legend Biotech Co., Ltd. Nef-containing t cells and methods of producing thereof
WO2020092455A2 (en) 2018-10-29 2020-05-07 The Broad Institute, Inc. Car t cell transcriptional atlas
US20220323495A1 (en) * 2019-03-27 2022-10-13 National Research Council Of Canada Antigen-binding agents that specifically bind epidermal growth factor receptor variant iii
CN114007642A (zh) 2019-04-30 2022-02-01 森迪生物科学公司 嵌合受体及其使用方法
WO2020232247A1 (en) 2019-05-14 2020-11-19 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
EP3747904A1 (en) * 2019-06-03 2020-12-09 Universität Regensburg Cd25-specific chimeric antigen receptors and their uses
MX2022001711A (es) * 2019-08-09 2022-05-10 A2 Biotherapeutics Inc Receptores en la superficie celular que responden a la perdida de heterocigosidad.
US20220411530A1 (en) * 2019-11-22 2022-12-29 Nantong Yichen Biopharma. Co. Ltd. PSMA Antibody and Use Thereof
US12006366B2 (en) 2020-06-11 2024-06-11 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
CA3188867A1 (en) 2020-08-20 2022-02-24 Xueyin Wang Compositions and methods for treating ceacam positive cancers
AU2021329371A1 (en) 2020-08-20 2023-04-20 A2 Biotherapeutics, Inc. Compositions and methods for treating mesothelin positive cancers
JP2023550148A (ja) * 2020-11-20 2023-11-30 シンシア・イノベーション・インコーポレイテッド がん免疫治療に用いられる武装二重car-t組成物及び方法
CN115491358A (zh) * 2021-06-17 2022-12-20 复星凯特生物科技有限公司 一种靶向b7-h3和folr1双打靶点car t的制备及应用
CN117940138A (zh) * 2021-07-01 2024-04-26 宁波茂行生物医药科技有限公司 靶向egfr的通用型car-t细胞及其制备方法
TWI823402B (zh) * 2021-07-21 2023-11-21 長聖國際生技股份有限公司 多特異性單域抗體嵌合抗原受體及t細胞銜接體、核酸、其表達細胞、其用途以及治療癌症之醫藥組合物
WO2023077068A1 (en) * 2021-10-28 2023-05-04 Skunkworx Bio, Inc. Novel binding agents related to glycoprotein-a

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050136035A1 (en) * 2003-06-03 2005-06-23 Derek Ko Cell specific replication-competent viral vectors comprising a self processing peptide cleavage site
PT3459560T (pt) * 2011-04-08 2021-05-24 Us Health Recetores de antigénio quimérico variante iii de recetor de fator de crescimento antiepidérmico e utilização dos mesmos para o tratamento de cancro
EP3626741A1 (en) * 2013-02-20 2020-03-25 The Trustees Of The University Of Pennsylvania Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
JP6420776B2 (ja) * 2013-03-05 2018-11-07 ベイラー カレッジ オブ メディスンBaylor College Of Medicine 免疫療法のためのエンゲージャー細胞
EP2970426B1 (en) * 2013-03-15 2019-08-28 Michael C. Milone Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
EP3027650B1 (en) * 2013-08-01 2021-01-13 Université catholique de Louvain Antibody binding a complex of human glycoprotein a repetitions predominant (garp) and latent tgf-beta-1
CA2956307A1 (en) * 2014-07-29 2016-02-04 Pfizer Inc. Egfrviii specific chimeric antigen receptors for cancer immunotherapy
HRP20240357T1 (hr) * 2014-12-24 2024-06-07 Autolus Limited Stanica
KR101997241B1 (ko) * 2015-05-21 2019-07-09 하푼 테라퓨틱스, 인크. 삼중특이성 결합 단백질 및 사용 방법
WO2017222593A1 (en) * 2016-06-24 2017-12-28 Icell Gene Therapeutics Llc Chimeric antigen receptors (cars), compositions and methods thereof
US11890301B2 (en) * 2015-08-28 2024-02-06 The Trustees Of The University Of Pennsylvania Methods and compositions for cells expressing a chimeric intracellular signaling molecule
US20180258149A1 (en) * 2015-09-17 2018-09-13 Novartis Ag Car t cell therapies with enhanced efficacy
US9567399B1 (en) * 2016-06-20 2017-02-14 Kymab Limited Antibodies and immunocytokines

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