JPWO2018183199A5 - - Google Patents
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- Publication number
- JPWO2018183199A5 JPWO2018183199A5 JP2020503250A JP2020503250A JPWO2018183199A5 JP WO2018183199 A5 JPWO2018183199 A5 JP WO2018183199A5 JP 2020503250 A JP2020503250 A JP 2020503250A JP 2020503250 A JP2020503250 A JP 2020503250A JP WO2018183199 A5 JPWO2018183199 A5 JP WO2018183199A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- renal
- population
- src
- biomaterial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 210000004027 cell Anatomy 0.000 claims 41
- 238000000034 method Methods 0.000 claims 25
- 239000012620 biological material Substances 0.000 claims 15
- 239000007972 injectable composition Substances 0.000 claims 15
- 108010010803 Gelatin Proteins 0.000 claims 12
- 239000008273 gelatin Substances 0.000 claims 12
- 229920000159 gelatin Polymers 0.000 claims 12
- 235000019322 gelatine Nutrition 0.000 claims 12
- 235000011852 gelatine desserts Nutrition 0.000 claims 12
- 238000002360 preparation method Methods 0.000 claims 11
- 239000003795 chemical substances by application Substances 0.000 claims 8
- 238000012544 monitoring process Methods 0.000 claims 6
- 102000008186 Collagen Human genes 0.000 claims 5
- 108010035532 Collagen Proteins 0.000 claims 5
- 229920001436 collagen Polymers 0.000 claims 5
- 230000035899 viability Effects 0.000 claims 5
- 241000283690 Bos taurus Species 0.000 claims 4
- 230000000975 bioactive effect Effects 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 4
- 230000014509 gene expression Effects 0.000 claims 4
- 239000000017 hydrogel Substances 0.000 claims 4
- 210000003734 kidney Anatomy 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- 210000004926 tubular epithelial cell Anatomy 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- 230000004663 cell proliferation Effects 0.000 claims 3
- 239000000499 gel Substances 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 3
- 230000000087 stabilizing effect Effects 0.000 claims 3
- 230000004083 survival effect Effects 0.000 claims 3
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 2
- 102100033366 Glutathione hydrolase 1 proenzyme Human genes 0.000 claims 2
- 101000997558 Homo sapiens Glutathione hydrolase 1 proenzyme Proteins 0.000 claims 2
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 2
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 2
- 239000002870 angiogenesis inducing agent Substances 0.000 claims 2
- 239000002260 anti-inflammatory agent Substances 0.000 claims 2
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 2
- 239000003963 antioxidant agent Substances 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 239000000969 carrier Substances 0.000 claims 2
- 108010015046 cell aggregation factors Proteins 0.000 claims 2
- 239000002771 cell marker Substances 0.000 claims 2
- 230000001413 cellular effect Effects 0.000 claims 2
- 230000001605 fetal effect Effects 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 239000003102 growth factor Substances 0.000 claims 2
- 239000002955 immunomodulating agent Substances 0.000 claims 2
- 229940121354 immunomodulator Drugs 0.000 claims 2
- 239000003018 immunosuppressive agent Substances 0.000 claims 2
- 238000002955 isolation Methods 0.000 claims 2
- 210000003292 kidney cell Anatomy 0.000 claims 2
- 239000006166 lysate Substances 0.000 claims 2
- 230000001483 mobilizing effect Effects 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 230000001817 pituitary effect Effects 0.000 claims 2
- 230000029663 wound healing Effects 0.000 claims 2
- 102100034459 Hepatitis A virus cellular receptor 1 Human genes 0.000 claims 1
- 101710185991 Hepatitis A virus cellular receptor 1 homolog Proteins 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 230000000735 allogeneic effect Effects 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 238000012832 cell culture technique Methods 0.000 claims 1
- 230000003915 cell function Effects 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 210000005257 cortical tissue Anatomy 0.000 claims 1
- 230000006862 enzymatic digestion Effects 0.000 claims 1
- 210000002744 extracellular matrix Anatomy 0.000 claims 1
- 239000006260 foam Substances 0.000 claims 1
- 238000011223 gene expression profiling Methods 0.000 claims 1
- 229960003444 immunosuppressant agent Drugs 0.000 claims 1
- 229940125721 immunosuppressive agent Drugs 0.000 claims 1
- 229940025708 injectable product Drugs 0.000 claims 1
- 238000011862 kidney biopsy Methods 0.000 claims 1
- 208000017169 kidney disease Diseases 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 230000002503 metabolic effect Effects 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 238000010791 quenching Methods 0.000 claims 1
- 230000000171 quenching effect Effects 0.000 claims 1
- 210000005084 renal tissue Anatomy 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 230000007704 transition Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762480166P | 2017-03-31 | 2017-03-31 | |
| US62/480,166 | 2017-03-31 | ||
| PCT/US2018/024353 WO2018183199A1 (en) | 2017-03-31 | 2018-03-26 | Injectable cell and scaffold compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020512406A JP2020512406A (ja) | 2020-04-23 |
| JP2020512406A5 JP2020512406A5 (https=) | 2022-03-28 |
| JPWO2018183199A5 true JPWO2018183199A5 (https=) | 2022-03-28 |
Family
ID=63676750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020503250A Pending JP2020512406A (ja) | 2017-03-31 | 2018-03-26 | 注射用の細胞および足場組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20200405913A1 (https=) |
| JP (1) | JP2020512406A (https=) |
| KR (1) | KR20190137112A (https=) |
| CN (2) | CN115645612A (https=) |
| AU (1) | AU2018243725A1 (https=) |
| CA (1) | CA3057498A1 (https=) |
| MX (1) | MX2019011545A (https=) |
| WO (1) | WO2018183199A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020223660A1 (en) * | 2019-05-02 | 2020-11-05 | Timothy Bertram | Treatment of kidney disease in subjects with kidney and/or urinary tract anomalies |
| US20220333147A1 (en) * | 2019-06-27 | 2022-10-20 | Board Of Regents, The University Of Texas System | Methods and compositions related to printed cellular niches for preserving and controlling synthetic microbial consortia |
| KR102160587B1 (ko) * | 2019-12-24 | 2020-09-28 | 주식회사 팡세 | 하이드로겔 액적 디핑용 액체 배스 조성물 |
| WO2021152578A1 (en) * | 2020-01-28 | 2021-08-05 | Kidneycure Ltd | Process for kidney cell manufacture and treatment |
| TWI779450B (zh) * | 2021-01-04 | 2022-10-01 | 國立清華大學 | 去細胞的細胞外基質及其製備方法與用途 |
| JP2023040935A (ja) * | 2021-09-10 | 2023-03-23 | 日機装株式会社 | 腎細胞の保管方法及び輸送方法 |
| EP4704933A1 (en) * | 2023-05-03 | 2026-03-11 | Volumina Medical SA | Devices and methods for preparing and conditioning biological assemblies for minimally invasive delivery for tissue engineering, cell therapies and other therapeutic applications |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6479064B1 (en) * | 1999-12-29 | 2002-11-12 | Children's Medical Center Corporation | Culturing different cell populations on a decellularized natural biostructure for organ reconstruction |
| CA3065694A1 (en) * | 2010-11-10 | 2012-05-18 | Inregen | Methods of forming injectable formulations for providing regenerative effects to an organ such as a kidney |
| KR20150065697A (ko) * | 2012-09-04 | 2015-06-15 | 안트로제네시스 코포레이션 | 조직 생성 방법 |
| RU2702721C2 (ru) * | 2012-10-24 | 2019-10-09 | инРиджен | Популяции клеток почек и их применение |
| CN106421917A (zh) * | 2016-11-08 | 2017-02-22 | 华南生物医药研究院 | 制备用于软骨损伤修复的组合物的方法 |
-
2018
- 2018-03-26 CN CN202210873005.XA patent/CN115645612A/zh active Pending
- 2018-03-26 MX MX2019011545A patent/MX2019011545A/es unknown
- 2018-03-26 WO PCT/US2018/024353 patent/WO2018183199A1/en not_active Ceased
- 2018-03-26 CA CA3057498A patent/CA3057498A1/en active Pending
- 2018-03-26 US US16/498,630 patent/US20200405913A1/en not_active Abandoned
- 2018-03-26 CN CN201880034715.5A patent/CN110662563A/zh active Pending
- 2018-03-26 KR KR1020197031832A patent/KR20190137112A/ko not_active Ceased
- 2018-03-26 AU AU2018243725A patent/AU2018243725A1/en not_active Abandoned
- 2018-03-26 JP JP2020503250A patent/JP2020512406A/ja active Pending
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